Long-Term Results of a Phase II Trial of Neoadjuvant Chemotherapy Followed by Esophagectomy for Locally Advanced Esophageal Neoplasm

Annals of Thoracic Surgery

Volumn 85, Issue 6, 2008, Pages 1930-1937

  Pennathur, Arjun ^a   Luketich, James D ^a   Landreneau, Rodney J ^a   Ward, Julie ^a   Christie, Neil A ^a   Gibson, Michael K ^b,c   Schuchert, Matthew ^a   Cooper, Kristi ^c   Land, Stephanie R ^c   Belani, Chandra P ^b,c  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; PACLITAXEL;

ADENOCARCINOMA; ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; ADOLESCENT; ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CONTINUOUS INFUSION; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG DOSE REDUCTION; ENDOSCOPIC ECHOGRAPHY; ESOPHAGUS CANCER; ESOPHAGUS RESECTION; FEMALE; FOLLOW UP; HUMAN; LAPAROSCOPY; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PREDICTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SIDE EFFECT; SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; SURGICAL MORTALITY; SURVIVAL TIME; THORACOSCOPY; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT;

ADENOCARCINOMA; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, SQUAMOUS CELL; CHEMOTHERAPY, ADJUVANT; CISPLATIN; COHORT STUDIES; COMBINED MODALITY THERAPY; DRUG ADMINISTRATION SCHEDULE; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; FEMALE; FLUOROURACIL; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIERS ESTIMATE; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; PACLITAXEL; PROGNOSIS; PROSPECTIVE STUDIES;

EID: 43849088182     PISSN: 00034975     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2008.01.097     Document Type: Article

References (22)

1. Enzinger P.C., and Mayer R.J. Esophageal cancer. N Engl J Med 349 (2003) 2241-2252
2. Medical Research Council Oesophageal Cancer Working Party. Surgical resection with or without preoperative chemotherapy in oesophageal cancer: a randomized trial. Lancet 359 (2002) 1727-1733
3. Roth J.A., and Putnam J.B. Surgery for cancer of the esophagus. Semin Oncol 21 (1994) 453-461
4. Kelsen D.P., Ginsberg R., Pajak T.F., et al. Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer. N Engl J Med 339 (1998) 1979-1984
5. Roth J.A., Pass H.I., Flanagan M.M., et al. Randomized clinical trial of preoperative and postoperative adjuvant chemotherapy with cisplatin, vindesine, and bleomycin for carcinoma of the esophagus. J Thorac Cardiovasc Surg 96 (1988) 242-248
6. Rowinsky E., Citardi M., Noe D.A., and Donehower R.C. Sequence-dependent cytotoxic effects due to combinations of cisplatin and the antimicrotubule agents taxol and vincristine. J Cancer Res Clin Oncol 119 (1993) 727-733
7. Patel G.F., Ren Q.F., Grem J., et al. Interaction of fluorouracil and paclitaxel in MCF-7 human breast carcinoma cells. Proc Am Assoc Cancer Res 35 (1994) 330
8. Ilson D.H., Ajani J., Bhalla K., et al. Phase II trial of paclitaxel, fluorouracil, and cisplatin in patients with advanced carcinoma of the esophagus. J Clin Oncol 16 (1998) 1826-1834
9. Luketich J.D., Ward J.A., Christie N.A., et al. Induction and postoperative chemotherapy with paclitaxel, cisplatin, and 5-fluorouracil regimen for carcinoma of the esophagus. Proc Am Soc Clin Oncol 20 (2001) (abstract 640)
10. Luketich J.D., Schauer P., Landreneau R.J., et al. Minimally invasive surgical staging is superior to endoscopic ultrasound in detecting lymph node metastases in esophageal cancer. J Thorac Cardiovasc Surg 114 (1997) 817-882
11. Luketich J.D., Alvelo-Rivera M., and Buenaventura P.O. Minimally invasive esophagectomy: outcomes in 222 patients. Ann Surg 238 (2003) 486-495
12. Krasna M.J., Reed C.E., Nedzwiecki D., et al. CALGB 9380: a prospective trial of the feasibility of throacoscopy/laproscopy in staging esophageal cancer. Ann Thorac Surg 71 (2001) 1073-1079
13. Luketich J.D., Schauer P.R., Meltzer C.C., et al. Role of positron emission tomography in staging esophageal cancer. Ann Thorac Surg 64 (1997) 765-769
14. Cunningham D., Allum W.H., Stenning S.P., et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med 355 (2006) 11-20
15. Forastiere A.A., Orringer M.B., Perez-Tamayo C., et al. Preoperative chemoradiation followed by transhiatal esophagectomy for carcinoma of the esophagus: final report. J Clin Oncol 11 (1993) 1118-1123
16. Urba S.G., Orringer M.B., Turrisi A., et al. Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma. J Clin Oncol 19 (2001) 305-313
17. Walsh T., Noonan N., Hollywood D., Kelly A., Keeling N., and Hennessy T.P.J. A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Engl J Med 335 (1996) 462-467
18. Reynolds J.V., Ravi N., Hollywood D., et al. Neoadjuvant chemoradiation may increase the risk of respiratory complications and sepsis after transthoracic esophagectomy. J Thorac Cardiovasc Surg 132 (2006) 549-555
19. Gebski V., Burmeister B., Smithers M., et al. Survival benefits from neoadjuvant chemoradiotherapy or chemotherapy in oesophageal carcinoma: a meta-analysis. Lancet Oncol 8 (2007) 226-234
20. Heath E.I., Burtness B.A., Heitmiller R.F., et al. Phase II evaluation of preoperative chemoradiation and postoperative adjuvant chemotherapy for squamous cell and adenocarcinoma of the esophagus. J Clin Oncol 18 (2000) 868-876
21. Korst R.J., Kansler A.L., Port J.L., et al. Downstaging of T or N predicts long-term survival after preoperative chemotherapy and radical resection for esophageal carcinoma. Ann Thorac Surg 82 (2006) 480-485
22. Rice T.W., Blackstone E.H., Adelstein D.J., et al. N1 esophageal carcinoma: the importance of staging and downstaging. J Thorac Cardiovasc Surg 121 (2001) 454-464