Cloning, characterization and phylogenetic analyses of members of three major venom families from a single specimen of Walterinnesia aegyptia,

Toxicon

Volumn 51, Issue 7, 2008, Pages 1245-1254

  Tsai, Hsin Yu ^a   Wang, Ying Ming ^a   Tsai, Inn Ho ^a,b  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

cDNA cloning and sequencing; Kunitz protease inhibitor; Phospholipase A2; Three finger toxin; Walterinnesia venom

Indexed keywords

COMPLEMENTARY DNA; PHOSPHOLIPASE A2; SERINE PROTEINASE INHIBITOR; SNAKE VENOM;

ARTICLE; CLONING; EGYPT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN PURIFICATION;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; COBRA NEUROTOXIN PROTEINS; DNA, COMPLEMENTARY; ELAPIDAE; GENE EXPRESSION PROFILING; MOLECULAR SEQUENCE DATA; PHYLOGENY; PROTEASE INHIBITORS; PROTEOME; TYPE C PHOSPHOLIPASES;

ELAPIDAE; OPHIOPHAGUS HANNAH; WALTERINNESIA; WALTERINNESIA AEGYPTIA;

EID: 43749123871     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.02.012     Document Type: Article

References (55)

1. Al-Shammary F.J., Al-Saleh S.S., and El-Shewemi S.E. Ultrastructural variations of rat myocardium due to Walterinnesia aegyptia snake envenomation. J. Electron. Microsc. (Tokyo) 47 (1998) 637-643
2. Altschul S.F., Madden T.L., Schäffer A.A., Zhang J., Zhang Z., Miller W., and Lipman D.J. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25 (1997) 3389-3402
3. Antil S., Servent D., and Menez A. Variability among the sites by which curaremimetic toxins bind to torpedo acetylcholine receptor, as revealed by identification of the functional residues of alpha-cobratoxin. J. Biol. Chem. 274 (1999) 34851-34858
4. Antil-Delbeke S., Gaillard C., Tamiya T., Corringer P.J., Changeux J.P., Servent D., and Ménez A. Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor. J. Biol. Chem. 275 (2000) 29594-29601
5. Apostoluk W., and Otlewski J. Variability of the canonical loop conformation in serine proteinases inhibitors and other proteins. Proteins: Struct. Funct. Genet. 32 (1998) 459-474
6. Carlsson F.H. Snake venom toxins. The primary structure of protein S4C11. A neurotoxin homologue from the venom of forest cobra (Naja melanoleuca). Biochim. Biophys. Acta 400 (1975) 310-321
7. Castoe T.A., Smith E.N., Brown R.M., and Parkison C.L. Higher-level phylogeny of Asian and American coralsnakes, their placement within the Elapidae (Squamata), and the systematic affinities of the enigmatic Asian coralsnake Hemibungarus calligaster (Wiegmann, 1834). Zool. J. Linn. Soc. 151 (2007) 809-831
8. 2 enzymes. Toxin Rev. 26 (2007) 143-167
9. Chang L.S., Lin S.K., Huang H.B., and Hsiao M. Genetic organization of alpha-bungarotoxins from Bungarus multicinctus (Taiwan banded krait): evidence showing that the production of alpha-bungarotoxin isotoxins is not derived from edited mRNAs. Nucleic Acids Res. 27 (1999) 3970-3975
10. Chang L.S., Chung C., Huang H.B., and Lin S.K. Purification and characterization of a chymotrypsin inhibitor from the venom of Ophiophagus hannah (king cobra). Biochem. Biophys. Res. Commun. 283 (2001) 862-867
11. 2 in pit viper venoms. Biochem. J. 381 (2004) 25-34
12. Cheng Y.C., Yan F.J., and Chang L.S. Taiwan cobra chymotrypsin inhibitor: cloning, functional expression and gene organization. Biochim. Biophys. Acta 1747 (2005) 213-220
13. 2 Enzyme: Structure, Function and Mechanism (1997), Wiley, UK 29-71
14. 2 from snake venom to human secreted forms. J. Mol. Evol. 31 (1990) 228-238
15. Felsenstein J. Confidence limits on phylogenies: an approach using the bootstrap. Evolution 39 (1985) 783-791
16. Felsenstein J. Phylip: The Phylogeny Interfence Package, Version 3.573 (1992), Computer program distributed by the University of Washington, Department of Genetics, Seattle, USA
17. Filippovich I., Sorokina N., Masci P.P., Jersey J.D., Whitaker A.N., Winzor D.J., Gaffney P.J., and Lavin M.F. A family of textilinin genes, two of which encode proteins with antihaemorrhagic properties. Br. J. Haematol. 119 (2002) 376-384
18. Flight S., Johnson L., Trabi M., Gaffney P., Lavin M., de Jersey J., and Masci P.P. Comparison of textilinin-1 with aprotinin as serine protease inhibitors and as antifibrinolytic agents. Pathophysiol. Haemost. Thromb. 34 (2005) 188-193
19. Fry B.G., Wuster W., Kini R.M., Brusic V., Khan A., Venkataraman D., and Rooney A.P. Molecular evolution and phylogeny of elapid snake venom three-finger toxins. J. Mol. Evol. 57 (2003) 110-129
20. Gitter S., and de Vries A. Symptomatology, pathology and treatment of bites of near eastern, European and north African snakes. In: Burchel W., Buckley E., and Delofeu V. (Eds). Venomous Animals and their Venoms vol. 1 (1968), Academic Press, New York 359-401
21. Grzesiak A., Helland R., Smalas A.O., Krowarsch D., Dadlez M., and Otlewski J. Substitutions at the P1′ position in BPTI strongly affect the association energy with serine proteinases. J. Mol. Biol. 301 (2000) 205-217
22. Guo X.X., Zeng L., Lee W.H., Zang Y., and Jin Y. Isolation and cloning of a metalloprotease from king cobra snake venom. Toxicon 49 (2007) 49954-49965
23. 2 from the venom of Ophiophagus hannah (king cobra): a novel cobra venom enzyme with "pancreatic loop". Arch. Biochem. Biophys. 15, 338 (1997) 150-156
24. 2 from Ophiophagus hannah snake venom. Life Sci. 61 (1997) 2211-2217
25. 125I-labelled Walterinnesia aegyptia venom and its specific antivenins: flash absorption and distribution of the venom and its toxin versus slow absorption and distribution of IgG, F(ab′)2 and F(ab) of the antivenin. Toxicon 36 (1998) 93-114
26. Karlsson E. Chemistry of protein toxins in snake venoms. In: Lee C.Y. (Ed). Snake Venoms, Handbook of Experimental Pharmacology vol. 52 (1979), Springer, Berlin 159-212
27. Kini R.M. Molecular moulds with multiple missions: functional sites in three-finger toxins. Clin. Exp. Pharmacol. Physiol. 29 (2002) 815-822
28. Laskowski Jr. M., and Kato I. Protein inhibitors of proteinases. Annu. Rev. Biochem. 49 (1980) 593-626
29. Lee C.Y., and Tsai M.C. Does the desert black snake inhibit release of acetylcholine from motor nerve endings. Toxicon 10 (1972) 659-660
30. Lee C.Y., Chen Y.M., and Mebs D. Chromatographic separation of the venom of Egyptian black snake (Walterinnesia aegyptia) and pharmacological characterization of its components. Toxicon 14 (1976) 275-281
31. Li J., Zhang H., Liu J., and Xu K. Novel genes encoding six kinds of three-finger toxins in Ophiophagus hannah (king cobra) and function characterization of two recombinant long-chain neurotoxins. Biochem. J. 398 (2006) 233-242
32. Liu C.S., and Lo T.B. Chemical studies of Bungarus fasciatus venom. J. Chin. Biochem. 23 (1994) 69-75
33. Liu C.S., Chen J.P., Chang C.M., Chen S.W., and Lo T.B. Amino acid sequence of a fasciatoxin-homologue, fasciatoxin-II in the venom of Bungarus fasciatus (banded karit). J. Chin. Biochem. Soc. 20 (1991) 33-39
34. 2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMR. Biochemistry 34 (1995) 7322-7334
35. Maniatis T., Fritsch E.F., and Sambrook J. Molecular Cloning, a Laboratory Manual (1989), Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
36. Menez A. Functional architectures of animal toxins: a clue to drug design?. Toxicon 36 (1998) 1557-1572
37. Millers E.K., Masci P.P., Lavin M.F., de Jersey J., and Guddat L.W. Crystallization and preliminary X-ray analysis of a Kunitz-type inhibitor, textilinin-1 from Pseudonaja textilis textilis. Acta Crystallogr. Sec. F 62 (2006) 642-645
38. Mullis K.B., and Faloona F.A. Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol. 155 (1987) 335-350
39. Nilson G., and Rastegar-Pouyani N. Walterinnesia aegyptia Lataste, 1887 (Ophidia: Elapidae) and the status of Naja morgani Mocquard 1905. Russ. J. Herpet. 14 (2007) 7-14
40. Ohno M., Menez R., Ogawa T., Danse J.M., Shimohigashi Y., Fromen C., Ducancel F., Zinn-Justin S., Le Du M.H., Boulain J.C., Tamiya T., and Menez A. Molecular evolution of snake toxins: is the functional diversity of snake toxins associated with a mechanism of accelerated evolution. Prog. Nucleic Acids Res. Mol. Biol. 59 (1998) 307-364
41. Pillet L., Tremeau O., Ducancel F., Drevet P., Zinn-Justin S., Pinkasfeld S., Boulain J.C., and Menez A. Genetic engineering of snake toxins. Role of invariant residues in the structural and functional properties of a curaremimetic toxin, as probed by site-directed mutagenesis. J. Biol. Chem. 268 (1993) 909-916
42. Rajagopalan N., Pung Y.F., Zhu Y.Z., Wong P.T., Kumar P.P., and Kini R.M. β-Cardiotoxin: a new three-finger toxin from Ophiophagus hannah (king cobra) venom with beta-blocker activity. FASEB J. 21 (2007) 3685-3695
43. Samejima Y., Aoki-Tomomatsu Y., Yanagisawa M., and Mebs D. Amino acid sequences of two neurotoxins from the venom of the Egyptian black snake (Walterinnesia aegyptia). Toxicon 35 (1997) 151-157
44. Schechter I., and Berger A. On the size of the active site in proteases. I. Papain. Biochem. Biophys. Res. Commun. (1967) 157-162
45. 2 from the venom of the desert black snake Walterinnesia aegyptia. Toxicon 18 (1980) 369-373
46. Slowinski J.B., Knight A., and Rooney A.P. Inferring species trees from gene trees: a phylogenetic analysis of the Elapidae (Serpentes) based on the amino acid sequences of venom proteins. Mol. Phylogenet. Evol. 8 (1997) 349-362
47. Thompson J.D., Higgins D.G., and Gibson T.J. Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22 (1994) 4673-4680
48. Tremeau O., Lemaire C., Drevet P., Pinkasfeld S., Ducancel F., Boulain J.C., Ménez A., et al. Genetic engineering of snake toxins. The functional site of erabutoxin a, as delineated by site-directed mutagenesis, includes variant residues. J. Biol. Chem. 270 (1995) 9362-9370
49. 2 from the venom gland of Bungarus candidus: cloning and sequence-comparison. Toxicon 40 (2002) 1363-1367
50. 2 and disintegrins of Protobothrops pit vipers. BBA-Prot. Proteom. 1702 (2004) 111-119
51. Tsetlin V.I., and Hucho F. Snake and snail toxins acting on nicotinic acetylcholine receptors: fundamental aspects and medical applications. FEBS Lett. 557 (2004) 9-13
52. 2 in a complex with a transition-state analogue. Science 250 (1990) 1560-1563
53. 2 determined from hemihedrally twinned crystal. Acta Crystallogr. D 59 (2003) 1574-1581
54. Zhou X.D., Jin Y., Lu Q.M., Li D.S., Zhu S.W., Wang W.Y., and Xiong Y.L. Purification, characterization and primary structure of a chymotrypsin inhibitor from Naja atra venom. Comp. Biochem. Physiol. 137B (2004) 219-224
55. Zupunski V., Kordis D., and Gubensek F. Adaptive evolution in the snake venom Kunitz/BPTI protein family. FEBS Lett. 547 (2003) 131-136