Replication-defective virus vaccine-induced protection of mice from genital herpes simplex virus 2 requires CD4 T cells

Virology

Volumn 376, Issue 1, 2008, Pages 205-210

  Morrison, Lynda A ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B cell deficient; CD4 T cells; HSV 2; Immunization; Vaginal

Indexed keywords

INFECTED CELL PROTEIN 8; LIVE VACCINE; REPLICATION DEFECTIVE HERPES SIMPLEX VIRUS 2; VIRUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; GENITAL HERPES; HERPES SIMPLEX VIRUS 2; IMMUNIZATION; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; VIRUS REPLICATION;

ANIMALS; BRAIN; BRAIN STEM; CD4-POSITIVE T-LYMPHOCYTES; GENITALIA; HERPES GENITALIS; HERPESVIRUS 2, HUMAN; HERPESVIRUS VACCINES; LYMPHOCYTE DEPLETION; MICE; MICE, INBRED BALB C; PLAQUE ASSAY; SEVERITY OF ILLNESS INDEX; SPINAL CORD; SURVIVAL ANALYSIS; VIRUS REPLICATION;

ANIMALIA; HUMAN HERPESVIRUS 2; MUS; REPLICATION DEFECTIVE VIRUSES; SIMPLEXVIRUS;

EID: 43749114944     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2008.03.010     Document Type: Article

References (50)

1. Asano M.S., and Ahmed R. CD8 T cell memory in B cell-deficient mice. J. Exp. Med. 183 (1996) 2165-2174
2. Banerjee K., Biswas P.S., and Rouse B.T. Elucidating the protective and pathologic T cell species in the virus-induced corneal immunoinflammatory condition herpetic stromal keratitis. J. Leukoc. Biol. 77 (2005) 24-32
3. Bishop S.A., and Hill T.J. Herpes simplex virus infection and damage in the central nervous system: immunomodulation with adjuvant, cyclophosphamide and cyclosporin A. Arch. Virol. 116 (1991) 57-68
4. Da Costa X.J., Bourne N., Stanberry L.R., and Knipe D.M. Construction and characterization of a replication-defective herpes simplex virus 2 ICP8 mutant strain and its use in immunization studies in a guinea pig model of genital disease. Virology 232 (1997) 1-12
5. Da Costa X.J., Morrison L.A., and Knipe D.M. Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection. Virology 288 (2001) 256-263
6. Deshpande S.P., Zheng M., Daheshia M., and Rouse B.T. Pathogenesis of herpes simplex virus-induced ocular immunoinflammatory lesions in B-cell-deficient mice. J. Virol. 74 (2000) 3517-3524
7. Dudley K.L., Bourne N., and Milligan G.N. Immune protection against HSV-2 in B-cell-deficient mice. Virology 270 (2000) 454-463
8. Eis-Hubinger A.M., Schmidt D.S., and Schneweis K.E. Anti-glycoprotein B monoclonal antibody protects T cell-depleted mice against herpes simplex virus infection by inhibition of virus replication at the inoculated mucous membranes. J. Gen. Virol. 74 (1993) 379-385
9. Field A.J., and Gottsch J.D. Persisting epithelial herpes simplex keratitis while on cyclosporin-A ointment. Aust. N. Z. J. Ophthalmol. 23 (1995) 333-334
10. Freeman E.E., Weiss H.A., Glynn J.R., Cross P.L., Whitworth J.A., and Hayes R.J. Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies. AIDS 20 (2006) 73-83
11. Gallichan W.S., and Rosenthal K.L. Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization. J. Exp. Med. 184 (1996) 1879-1890
12. Gao M., and Knipe D.M. Genetic evidence for multiple nuclear functions of the herpes simplex virus ICP8 DNA-binding protein. J. Virol. 63 (1989) 5258-5267
13. Harandi A.M., Svennerholm B., Holmgren J., and Eriksson K. Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice. J. Gen. Virol. 82 (2001) 845-853
14. Homann D., Tishon A., Berger D.P., Weigle W.O., von Herrath M.G., and Oldstone M.B. Evidence for an underlying CD4 helper and CD8 T-cell defect in B-cell-deficient mice: failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from muMT/muMT mice. J. Virol. 72 (1998) 9208-9216
15. Kamali A., Nunn A.J., Mulder D.W., Van Dyck E., Dobbins J.G., and Whitworth J.A. Seroprevalence and incidence of genital ulcer infections in a rural Ugandan population. Sex. Transm. Infect. 75 (1999) 98-102
16. Kemball C.C., Lee E.D., Szomolanyi-Tsuda E., Pearson T.C., Larsen C.P., and Lukacher A.E. Costimulation requirements for antiviral CD8+ T cells differ for acute and persistent phases of polyoma virus infection. J. Immunol. 176 (2006) 1814-1824
17. Kimberlin D.W., and Whitley R.J. Neonatal herpes: what have we learned. Semin. Pediatr. Infect. Dis. 16 (2005) 7-16
18. Kitamura D., Roes J., Kuhn R., and Rajewsky K. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene. Nature 350 (1991) 423-426
19. Knipe D.M., and Spang A.E. Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus. J. Virol. 43 (1982) 314-324
20. Kolaitis G., Doymaz M., and Rouse B.T. Demonstration of MHC class II-restricted cytotoxic T lymphocytes in mice against herpes simplex virus. Immunology 71 (1990) 101-106
21. Kuklin N.A., Daheshia M., Chun S., and Rouse B.T. Role of mucosal immunity in herpes simplex virus infection. J. Immunol. 160 (1998) 5998-6003
22. Liu T., Khanna K.M., Chen X., Fink D.J., and Hendricks R.L. CD8(+) T cells can block herpes simplex virus type 1 (HSV-1) reactivation from latency in sensory neurons. J. Exp. Med. 191 (2000) 1459-1466
23. McDermott M.R., Smiley J.R., Leslie P., Brais J., Rudzroga H.E., and Bienenstock J. Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2. J. Virol. 51 (1984) 747-753
24. McDermott M.R., Goldsmith C.H., Rosenthal K.L., and Brais L.J. T lymphocytes in genital lymph nodes protect mice from intravaginal infection with herpes simplex virus type 2. J. Infect. Dis. 159 (1989) 460-466
25. McDermott M.R., Brais L.J., and Evelegh M.J. Mucosal and systemic antiviral antibodies in mice inoculated intravaginally with herpes simplex virus type 2. J. Gen. Virol. 71 (1990) 1497-1504
26. McKendall R.R., Klassen T., and Baringer J.R. Host defenses in herpes simplex infections of the nervous system: effect of antibody on disease and viral spread. Infect. Immun. 23 (1979) 305-311
27. Milligan G.N., and Bernstein D.I. Analysis of herpes simplex virus-specific T cells in the murine female genital tract following genital infection with herpes simplex virus type 2. Virology 212 (1995) 481-489
28. Milligan G.N., and Bernstein D.I. Generation of humoral immune responses against herpes simplex virus type 2 in the murine female genital tract. Virology 206 (1995) 234-241
29. Milligan G.N., and Bernstein D.I. Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract. Virology 229 (1997) 259-268
30. Milligan G.N., Bernstein D.I., and Bourne N. T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2. J. Immunol. 160 (1998) 6093-6100
31. Milligan G.N., Dudley-McClain K.L., Young C.G., and Chu C.F. T-cell-mediated mechanisms involved in resolution of genital herpes simplex virus type 2 (HSV-2) infection of mice. J. Reprod. Immunol. 61 (2004) 115-127
32. Morrison L.A., and Knipe D.M. Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1. Virology 220 (1996) 402-413
33. Morrison L.A., Da Costa X.J., and Knipe D.M. Influence of mucosal and parenteral immunization with a replication-defective mutant of HSV-2 on immune responses and protection from genital challenge. Virology 243 (1998) 178-187
34. Morrison L.A., Zhu L., and Thebeau L.G. Vaccine-induced serum immunoglobin contributes to protection from herpes simplex virus type 2 genital infection in the presence of immune T cells. J. Virol. 75 (2001) 1195-1204
35. Obasi A., Mosha F., Quigley M., Sekirassa Z., Gibbs T., Munguti K., Todd J., Grosskurth H., Mayaud P., Changalucha J., Brown D., Mabey D., and Hayes R. Antibody to herpes simplex virus type 2 as a marker of sexual risk behavior in rural Tanzania. J. Infect. Dis. 179 (1999) 16-24
36. Openshaw H., Asher L.V., Wohlenberg C., Sekizawa T., and Notkins A.L. Acute and latent infection of sensory ganglia with herpes simplex virus: immune control and virus reactivation. J. Gen. Virol. 44 (1979) 205-215
37. Parr E.L., and Parr M.B. Immunoglobulin G, plasma cells, and lymphocytes in the murine vagina after vaginal or parenteral immunization with attenuated herpes simplex virus type 2. J. Virol. 72 (1998) 5137-5145
38. Parr M.B., and Parr E.L. Mucosal immunity to herpes simplex virus type 2 infection in the mouse vagina is impaired by in vivo depletion of T lymphocytes. J. Virol. 72 (1998) 2677-2685
39. Parr M.B., and Parr E.L. The role of gamma interferon in immune resistance to vaginal infection by herpes simplex virus type 2 in mice. Virology 258 (1999) 282-294
40. Parr M.B., and Parr E.L. Immunity to vaginal herpes simplex virus-2 infection in B-cell knockout mice. Immunology 101 (2000) 126-131
41. Parr M.B., Kepple L., McDermott M.R., Drew M.D., Bozzola J.J., and Parr E.L. A mouse model for studies of mucosal immunity to vaginal infection by herpes simplex virus type 2. Lab. Invest. 70 (1994) 369-380
42. Parr E.L., Bozzola J.J., and Parr M.B. Immunity to vaginal infection by herpes simplex virus type 2 in adult mice: characterization of the immunoglobulins in vaginal mucus. J. Reprod. Immunol. 38 (1998) 15-30
43. Schmidt D.S., Eis-Hubinger A.M., and Schneweis K.E. The role of the immune system in establishment of herpes simplex virus latency-studies using CD4+ T-cell depleted mice. Arch. Virol. 133 (1993) 179-187
44. Schneweis K.E., Brado M., Ebers B., Friedrich A., Olbrich M., and Schuler W. Immunological mechanisms giving rise to latency of herpes simplex virus in the spinal ganglia of the mouse. Med. Microbiol. Immunol. 177 (1988) 1-8
45. Stanberry L.R., Spruance S.L., Cunningham A.L., Bernstein D.I., Mindel A., Sacks S., Tyring S., Aoki F.Y., Slaoui M., Denis M., Vandepapeliere P., and Dubin G. Glycoprotein-D-adjuvant vaccine to prevent genital herpes. N. Engl. J. Med. 347 (2002) 1652-1661
46. Thebeau L.G., and Morrison L.A. B7 costimulation plays an important role in protection from herpes simplex virus type 2-mediated pathology. Virology 76 (2002) 2563-2566
47. Topham D.J., Tripp R.A., Hamilton-Easton A.M., Sarawar S.R., and Doherty P.C. Quantitative analysis of the influenza virus-specific CD4+ T cell memory in the absence of B cells and Ig. J. Immunol. 157 (1996) 2947-2952
48. van Lint A., Ayers M., Brooks A.G., Coles R.M., Heath W.R., and Carbone F.R. Herpes simplex virus-specific CD8+ T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation. J. Immunol. 172 (2004) 392-397
49. Wald A., and Link K. Risk of human immunodeficiency virus infection in herpes simplex virus type 2-seropositive persons: a meta-analysis. J. Infect. Dis. 185 (2002) 45-52
50. Xu F., Lee F.K., Morrow R.A., Sternberg M.R., Luther K.E., Dubin G., and Markowitz L.E. Seroprevalence of herpes simplex virus type 1 in children in the United States. J. Pediatr. 151 (2007) 374-377