Binding of recombinant human coagulation factor VIII to lipid nanotubes

FEBS Letters

Volumn 582, Issue 12, 2008, Pages 1657-1660

  Parmenter, Christopher D J ^a   Stoilova McPhie, Svetla ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Coagulation factor VIII; Cryo electron microscopy; Image analysis; Lipid nanotubes; Lipid protein interactions

Indexed keywords

NANOTUBE; PHOSPHATIDYLSERINE; RECOMBINANT BLOOD CLOTTING FACTOR 8;

ARTICLE; CONFORMATIONAL TRANSITION; ELECTRON MICROSCOPY; LIPID COMPOSITION; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN BINDING;

CRYOELECTRON MICROSCOPY; FACTOR VIII; HEMOPHILIA A; HUMANS; LIPID BILAYERS; NANOTUBES; PHOSPHATIDYLSERINES; PROTEIN CONFORMATION; RECOMBINANT PROTEINS;

EID: 43749110693     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.04.018     Document Type: Article

References (20)

1. Kemball-Cook, G., Tuddenham, E.G.D. and Wacey, A.I. (1998) The factor VIII structure and mutation resource site: HAMSTeRS version 4. Nucl. Acids Res. 26, 216-219.
2. Saenko E.L., Ananyeva N.M., Tuddenham E.G.D., and Kemball-Cook G. Factor VIII - novel insights into form and function. Br. J. Haematol. 119 (2002) 323-331
3. Gilbert G.E., Furie B.C., and Furie B. Binding of human factor VIII to phospholipid vesicles. J. Biol. Chem. 265 (1990) 815-822
4. van Dieijen G., Tans G., Rosing J., and Hemker H.C. The role of phospholipid and factor VIIIa in the activation of bovine factor X. J. Biol. Chem. 256 (1981) 3433-3442
5. Wood W.I., Capon D.J., Simonsen C.C., Eaton D.L., Gitscher J., Keyt B., Seeburg P.H., Smith D.H., Hollingshead P., Wion K.L., Delwart E., Tuddenham E.G.D., Verhar G.A., and Lawn R.M. Expression of active human factor VIII from recombinant DNA clones. Nature (1984) 330-337
6. Shen B.W., Spiegel P.C., Chang C.-H., Huh J.-W., Lee J.-S., Kim J., Kim Y.-H., and Stoddard B.L. The tertiary structure and domain organization of coagulation factor VIII. Blood 111 (2008) 1240-1247
7. Fay P.J. Activation of factor VIII and mechanism of cofactor action. Blood Rev. 18 (2004) 1-15
8. Fay P.J., Haidaris P.J., and Smudzin T.M. Human factor VIIIa subunit structure. Reconstruction of factor VIIIa from the isolated A1/A3-C1-C2 dimer and A2 subunit. J. Biol. Chem. 266 (1991) 8957-8962
9. Sandberg H., Almstedt A., Brandt J., Gray E., Holmquist L., Oswaldsson U., Sebring S., and Mikaelsson M. Structural and functional characteristics of the B-domain-deleted recombinant factor VIII protein, r-FVIII SQ. Thromb. Haemostat. 85 (2001) 93-100
10. Jankowski M.A., Patel H., Rouse J.C., Marzilli L.A., Weston S.B., and Sharpe P.J. Defining 'full-length' recombinant factor VIII: a comparative structural analysis. Haemophilia 13 (2007) 30-37
11. Wilson-Kubalek E.M., Brown R.E., Celia H., and Milligan R.A. Lipid nanotubes as substrates for helical crystallization of macromolecules. PNAS 95 (1998) 8040-8045
12. Wilson-Kubalek E.M., Merrill Jr. A.H., and Hannun Y.A. Preparation of functionalized lipid tubules for electron crystallography of macromolecules. Methods in Enzymology (2000), Academic Press
13. Egelman E.H. A robust algorithm for the reconstruction of helical filaments using single-particle methods. Ultramicroscopy 85 (2000) 225-234
14. Egelman E.H. The iterative helical real space reconstruction method: surmounting the problems posed by real polymers. J. Struct. Biol. 157 (2007) 83-94
15. Dang T.X., Farah S.J., Gast A., Robertson C., Carragher B., Egelman E., and Wilson-Kubalek E.M. Helical crystallization on lipid nanotubes: streptavidin as a model protein. J. Struct. Biol. 150 (2005) 90-99
16. Parmenter C.D.J., Cane M.C., Zhang R., and Stoilova-McPhie S. Cryo-electron microscopy of coagulation Factor VIII bound to lipid nanotubes. Biochem. Biophys. Res. Commun. 366 (2008) 288-293
17. Mitchell D.R.G., and Shaffer B. Scripting-customised microscopy tools for Digital Micrograph™. Ultramicroscopy 103 (2005) 319-332
18. Stoilova-McPhie S., Villoutreix B.O., Mertens K., Kembal-Cook G., and Holzenburg A. 3-Dimensional structure of membrane-bound coagulation factor VIII: modeling of the factor VIII heterodimer within a 3-dimensional density map derived by electron crystallography. Blood 99 (2002) 1215-1223
19. Stoilova-Mcphie S., Parmenter C.D.J., Segers K., Villoutreix B.O., and Nicolaes G.A.F. Defining the structure of membrane-bound human blood coagulation factor Va. J. Thromb. Haemostat. 6 (2008) 76-82
20. Shaw D.J. Introduction to Colloid and Surface Chemistry. 4th ed. (1992), Butterworth-Heinemann, Boston. 0 7506 1182 0 pp. 1-20.