Polymorphisms of TP53 Arg72Pro, but not p73 G4C14>A4TA4 and p21 Ser31Arg, contribute to risk of cutaneous melanoma

Journal of Investigative Dermatology

Volumn 128, Issue 6, 2008, Pages 1585-1588

  Li, Chunying ^a,c   Chen, Kexin ^a   Liu, Zhensheng ^a   Wang, Li E ^a   Gershenwald, Jeffrey E ^a   Lee, Jeffrey E ^a   Prieto, Victor G ^a   Duvic, Madeleine ^b   Grimm, Elizabeth A ^a   Wei, Qingyi ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b University of Texas Health Science Center at Houston   (United States)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P21; PROTEIN P53; PROTEIN P73;

APOPTOSIS; CANCER RISK; CELL CYCLE ARREST; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; LETTER; MELANOMA; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ULTRAVIOLET RADIATION;

EID: 43749086239     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701186     Document Type: Letter

References (18)

1. J. Han D.G. Cox G.A. Colditz D.J. Hunter The p53 codon 72 polymorphism, sunburns, and risk of skin cancer in US Caucasian women Mol Carcinog 45 2006 694 700
2. Z. Hu X. Miao H. Ma W. Tan X. Wang D. Lu Dinucleotide polymorphism of p73 gene is associated with a reduced risk of lung cancer in a Chinese population Int J Cancer 114 2005 455 460
3. S.P. Hussain C.C. Harris p53 mutation spectrum and load: the generation of hypotheses linking the exposure of endogenous or exogenous carcinogens to human cancer Mutat Res 428 1999 23 32
4. C.A. Jost M.C. Marin W.G. Kaelin Jr p73 is a simian [correction of human] p53-related protein that can induce apoptosis Nature 389 1997 191 194
5. W.G. Kaelin Jr The p53 gene family Oncogene 18 1999 7701 7705
6. M. Kaghad H. Bonnet A. Yang L. Creancier J.C. Biscan A. Valent Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers Cell 90 1997 809 819
7. R. Konishi S. Sakatani K. Kiyokane K. Suzuki Polymorphisms of p21 cyclin-dependent kinase inhibitor and malignant skin tumors J Dermatol Sci 24 2000 177 183
8. G. Li Z. Liu E.M. Sturgis Q. Shi R.M. Chamberlain M.R. Spitz Genetic polymorphisms of p21 are associated with risk of squamous cell carcinoma of the head and neck Carcinogenesis 26 2005 1596 1602
9. G. Li L.E. Wang R.M. Chamberlain C.I. Amos M.R. Spitz Q. Wei p73 G4C14-to-A4T14 polymorphism and risk of lung cancer Cancer Res 64 2004 6863 6866
10. F. Mouriaux F. Casagrande M.J. Pillaire S. Manenti F. Malecaze J.M. Darbon Differential expression of G1 cyclins and cyclin-dependent kinase inhibitors in normal and transformed melanocytes Invest Ophthalmol Vis Sci 39 1998 876 884
11. J.E. Povey F. Darakhshan K. Robertson Y. Bisset M. Mekky J. Rees DNA repair gene polymorphisms and genetic predisposition to cutaneous melanoma Carcinogenesis 28 2007 1087 1093
12. A.I. Robles C.C. Harris p53-mediated apoptosis and genomic instability diseases Acta Oncol 40 2001 696 701
13. H. Shen Z. Liu S.S. Strom M.R. Spitz J.E. Lee J.E. Gershenwald p53 codon 72 Arg homozygotes are associated with an increased risk of cutaneous melanoma J Invest Dermatol 121 2003 1510 1514
14. I. Stefanaki A.J. Stratigos G. Dimisianos V. Nikolaou O. Papadopoulos D. Polydorou p53 codon 72 Pro homozygosity increases the risk of cutaneous melanoma in individuals with dark skin complexion and among noncarriers of melanocortin 1 receptor red hair variants Br J Dermatol 156 2007 357 362
15. S. Tuve S.N. Wagner B. Schittek B.M. Putzer Alterations of DeltaTA-p 73 splice transcripts during melanoma development and progression Int J Cancer 108 2004 162 166
16. M.J. Vidal F. Loganzo Jr A.R. De Oliveira N.K. Hayward A.P. Albino Mutations and defective expression of the WAF1 p21 tumour-suppressor gene in malignant melanomas Melanoma Res 5 1995 243 250
17. X.Q. Wang W.M. Ongkeko A.W. Lau K.M. Leung R.Y. Poon A possible role of p73 on the modulation of p53 level through MDM2 Cancer Res 61 2001 1598 1603
18. Y. Xiong G.J. Hannon H. Zhang D. Casso R. Kobayashi D. Beach p21 is a universal inhibitor of cyclin kinases Nature 366 1993 701 704