Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression

British Journal of Cancer

Volumn 98, Issue 10, 2008, Pages 1653-1661

  Hays, L E ^a,b,c   Zodrow, D M ^a,c   Yates, J E ^a,c   Deffebach, M E ^b,c   Jacoby, D B ^b   Olson, S B ^a   Pankow, J F ^a   Bagby, G C ^a,b,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

Carcinogenesis; Fanconi anaemia; Lung cancer; Mechanisms of genomic alterations; Tobacco

Indexed keywords

CARCINOGEN; CIGARETTE SMOKE CONDENSATE; FANCONI ANEMIA GROUP C PROTEIN; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA GROUP G PROTEIN; MESSENGER RNA;

APOPTOSIS; ARTICLE; CELL POPULATION; CHROMOSOMAL INSTABILITY; CIGARETTE SMOKING; CLONE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG CARCINOGENESIS; LUNG CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM;

APOPTOSIS; BRONCHIAL NEOPLASMS; CELL SURVIVAL; CHROMOSOMAL INSTABILITY; DOWN-REGULATION; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOBLOTTING; RESPIRATORY MUCOSA; RNA; SMOKING; TOBACCO SMOKE POLLUTION; TUMOR MARKERS, BIOLOGICAL;

EID: 43649107543     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604362     Document Type: Article

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