AMPA receptor potentiation can prevent ethanol-induced intoxication

Neuropsychopharmacology

Volumn 33, Issue 7, 2008, Pages 1713-1723

  Jones, Nicholas ^a   Messenger, Marcus J ^b   O'Neill, Michael J ^b   Oldershaw, Anna ^a   Gilmour, Gary ^b   Simmons, Rosa M A ^b   Iyengar, Smriti ^b   Libri, Vincenzo ^b,c   Tricklebank, Mark ^b   Williams, Steve C R ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ELI LILLY AND COMPANY   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Alcohol; AMPA receptor; Ethanol; fMRI; Glutamate

Indexed keywords

ALCOHOL; AMPA RECEPTOR; CARBON 14; DEOXYGLUCOSE; GLUCOSE; N [2 [4 (4 CYANOPHENYL)PHENYL]PROPYL] 2 PROPANESULFONAMIDE; N [2 [4' (2 METHYLSULFONAMIDOETHYL)BIPHENYL 4 YL]PROPYL] 2 PROPANESULFONAMIDE;

ALCOHOL INTOXICATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BLOOD OXYGENATION; CONTROLLED STUDY; COORDINATION DISORDER; DOSE RESPONSE; DRUG ALCOHOL INTERACTION; DRUG POTENTIATION; DRUG TOLERABILITY; FOOD; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLUCOSE BRAIN LEVEL; GLUCOSE UTILIZATION; INSTRUMENTAL CONDITIONING; MALE; MOTOR COORDINATION; NEUROTRANSMISSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RAT;

ALCOHOLIC INTOXICATION; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BIPHENYL COMPOUNDS; BRAIN; BRAIN MAPPING; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; EXCITATORY AMINO ACID AGONISTS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MOTOR ACTIVITY; OXYGEN; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; SULFONAMIDES; TIME FACTORS;

EID: 43649103410     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301562     Document Type: Article

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