Erythropoietin and polyneuropathy in older persons

Mechanisms of Ageing and Development

Volumn 129, Issue 6, 2008, Pages 299-303

  Lauretani, Fulvio ^a,e   Bandinelli, Stefania ^b   Strotmeyer, Elsa S ^c   Corsi, Anna Maria ^a   Di Iorio, Angelo ^d   Guralnik, Jack M ^e   Ferrucci, Luigi ^e  

^a Tuscany Regional Health Agency   (Italy)

^b Azienda Sanitaria di Firenze   (Italy)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF CHIETI   (Italy)

^e NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

EPO; InCHIANTI study; Polyneuropathy; Population based study; Prevention

Indexed keywords

ERYTHROPOIETIN;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ELDERLY CARE; ELECTRONYSTAGMOGRAPHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MUSCLE ACTION POTENTIAL; NERVE CONDUCTION; PARAMETER; PERIPHERAL NERVE; POLYNEUROPATHY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

AGED; AGED, 80 AND OVER; AGING; ANTHROPOMETRY; ERYTHROPOIETIN; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROLOGIC EXAMINATION; PERIPHERAL NERVOUS SYSTEM; POLYNEUROPATHIES; PROBABILITY;

EID: 43649095999     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2008.02.006     Document Type: Article

References (27)

1. American Diabetes Association. An up-to-date summary of the current classification of diabetes and standards of the care for the management of diabetes patients, including the goals of treatment. Diabetes Care 21 Suppl. (1998) 1
2. Bianchi R., Buyukakilli B., Brines M., Savino C., Cavaletti G., Oggioni N., Lauria G., Borgna M., Lombardi R., Cimen B., Comelekoglu U., Kanik A., Tataroglu C., Cerami A., and Ghezzi P. Erythropoietin both protects from and reverses experimental diabetic neuropathy. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 823-828
3. Buschbacher R.M. Peroneal nerve motor conduction to the extensor digitorum brevis. Am. J. Phys. Med. Rehabil. 78 (1999) S26-S31
4. Campana W.M., and Myers R.R. Exogenous erythropoietin protects against dorsal root ganglion apoptosis and pain following peripheral nerve injury. Eur. J. Neurosci. 18 (2003) 1497-1506
5. Chong Z.Z., Kang J.Q., and Maiese K. Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases. Circulation 106 (2002) 2973-2979
6. Digicaylioglu M., Bichet S., Marti H.H., Wenger R.H., Rivas L.A., Bauer C., and Gassmann M. Localization of specific erythropoietin binding sites in defined areas of the mouse brain. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 3717-3720
7. Digicaylioglu M., and Lipton S.A. Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412 (2001) 641-647
8. Ehrenreich H., Hasselblatt M., Dembowski C., Cepek L., Lewczuk P., Stiefel M., Rustenbeck H.H., Breiter N., Jacob S., Knerlich H.F., Bohn M., Poser W., Ruther E., Kochen M., Gefeller O., Gleiter C., Wessel T.C., De Ryck M., Itri L., Prange H., Cerami A., Brines M., and Siren A.L. Erythropoietin therapy for acute stroke is both safe and beneficial. Mol. Med. 8 (2002) 495-505
9. England J.D., Gronseth G.S., Franklin G., Miller R.G., Asbury A.K., Carter G.T., Cohen J.A., Fisher M.A., Howard J.F., Kinsella L.J., Latov N., Lewis R.A., Low P.A., and Sumner A.J. American Academy of Neurology; American Association of Electrodiagnostic Medicine; American Academy of Physical Medicine and Rehabilitation. Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. Neurology 64 (2005) 199-207
10. Ferrucci L., Bandinelli S., Cavazzini C., Lauretani F., Corsi A., Bartali B., Cherubini A., Launer L., and Guralnik J.M. Neurological examination findings to predict limitations in mobility and falls in older persons without a history of neurological disease. Am. J. Med. 116 (2004) 807-815
11. Ferrucci L., Bandinelli S., Benvenuti E., Di Iorio A., Macchi C., Harris T.B., and Guralnik J.M. Subsystems contributing to the decline in ability to walk: bridging the gap between epidemiology and geriatric practice in the InCHIANTI study. J. Am. Geriatr. Soc. 48 (2000) 1618-1625
12. Goldman S.A., and Nedergaard M. Erythropoietin strikes a new cord. Nat. Med. 8 (2002) 785-787
13. Gorio A., Gokmen N., Erbayraktar S., Yilmaz O., Madaschi L., Cichetti C., Di Giulio A.M., Vardar E., Cerami A., and Brines M. Recombinant human erythropoietin counteracts secondary injury and markedly enhances neurological recovery from experimental spinal cord trauma. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 9450-9455
14. Guralnik J.M., Fried L.P., Simonsick E.M., Kasper J.D., and Lafferty M.E. The Women's Health and Aging Study-Health and Social Characteristics of Older Women with Disability (1995), National Institute on Aging, Bethesda, MD (NIH Pub. No. 95-4009)
15. Hassan K., Simri W., Rubenchik I., Manelis J., Gross B., Shasha S.M., and Kristal B. Effect of erythropoietin therapy on polyneuropathy in predialytic patients. J. Nephrol. 16 (2003) 121-125
16. Hoke A. Neuroprotection in the peripheral nervous system: rationale for more effective therapies. Arch. Neurol. 63 (2006) 1681-1685
17. Ilsa working group. Epidemiology of distal symmetrical neuropathies in the Italian elderly. Neurology 68 (2007) 1460-1467
18. Keswani S.C., Buldanlioglu U., Fischer A., Reed N., Polley M., Liang H., Zhou C., Jack C., Leitz G.J., and Hoke A. A novel endogenous erythropoietin mediated pathway prevents axonal degeneration. Ann. Neurol. 56 (2004) 815-826
19. Kilic U., Kilic E., Soliz J., Bassetti C.I., Gassmann M., and Hermann D.M. Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J. 19 (2005) 249-251
20. Lauretani F., Bandinelli S., Benedetta B., Cherubini A., Iorio A.D., Ble A., Giacomini V., Corsi A.M., Guralnik J.M., and Ferrucci L. Omega-6 and omega-3 fatty acids predict accelerated decline of peripheral nerve function in older persons. Eur. J. Neurol. 14 (2007) 801-808
21. Lauretani F., Bandinelli S., Bartali B., Iorio A.D., Giacomini V., Corsi A.M., Guralnik J.M., and Ferrucci L. Axonal degeneration affects muscle density in older men and women. Neurobiol. Aging 27 (2006) 1145-1154
22. Lipton S.A. Erythropoietin for neurologic protection and diabetic neuropathy. N. Engl. J. Med. 350 (2004) 2516-2517
23. Maiese K., Li F., and Chong Z.Z. New avenues of exploration for erythropoietin. JAMA 293 (2005) 90-95
24. Morishita E., Masuda S., Nagao M., Yasuda Y., and Sasaki R. Erythropoietin receptor is expressed in rat hippocampal and cerebral cortical neurons, and erythropoietin prevents in vitro glutamate-induced neuronal death. Neuroscience 76 (1997) 105-116
25. Sakanaka M., Wen T.C., Matsuda S., Masuda S., Morishita E., Nagao M., and Sasaki R. In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 4635-4640
26. Scarlato M., Previstali S.C., Carpo M., Pareyson D., Briani C., Del Bo R., Nobile-Orazio E., Quattrini A., and Comi G.P. Polyneuropathy in POEMS syndrome: role of angiogenic factors in the pathogenesis. Brain 128 (2005) 1911-1920
27. Shingo T., Sorokan S.T., Shimazaki T., and Weiss S. Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J. Neurosci. 21 (2001) 9733-9743