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Volumn 20, Issue 3, 2008, Pages 307-314

Vascular endothelial growth factor (VEGF) gene therapy using a nonviral gene delivery system improves erectile function in a diabetic rat model

Author keywords

Diabetic model; Erectile dysfunction; Gene therapy; VEGF

Indexed keywords

GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; MESSENGER RNA; VASCULOTROPIN; VASCULOTROPIN GREEN FLUORESCENT PROTEIN FUSION PROTEIN;

EID: 43649087967     PISSN: 09559930     EISSN: 14765489     Source Type: Journal    
DOI: 10.1038/ijir.2008.1     Document Type: Article
Times cited : (40)

References (19)
  • 1
    • 0037300192 scopus 로고    scopus 로고
    • Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats
    • Rogers RS, Graziottin TM, Lin CS, Lue TF. Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats. Int J Imp Res 2003; 15: 26-37.
    • (2003) Int J Imp Res , vol.15 , pp. 26-37
    • Rogers, R.S.1    Graziottin, T.M.2    Lin, C.S.3    Lue, T.F.4
  • 3
    • 33845774784 scopus 로고    scopus 로고
    • hMaxi-K gene transfer in males with erectile dysfunction: Results of the first human trial
    • Melman A, Bar-Chama N, McCullough A, Davies K, Christ G. hMaxi-K gene transfer in males with erectile dysfunction: results of the first human trial. Hum Gene Ther 2006; 17: 1165-1176.
    • (2006) Hum Gene Ther , vol.17 , pp. 1165-1176
    • Melman, A.1    Bar-Chama, N.2    McCullough, A.3    Davies, K.4    Christ, G.5
  • 5
    • 0037404943 scopus 로고    scopus 로고
    • Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats
    • Bivalacqua TJ, Usta MF, Champion HC, Adams D, Namara DB, Abdel-Mageed AB et al. Gene transfer of endothelial nitric oxide synthase partially restores nitric oxide synthesis and erectile function in streptozotocin diabetic rats. J Urol 2003; 169: 1911-1917.
    • (2003) J Urol , vol.169 , pp. 1911-1917
    • Bivalacqua, T.J.1    Usta, M.F.2    Champion, H.C.3    Adams, D.4    Namara, D.B.5    Abdel-Mageed, A.B.6
  • 6
    • 17444373469 scopus 로고    scopus 로고
    • Gene transfer of vasoactive intestinal polypeptide into the penis improves erectile response in the diabetic rat
    • Shen ZJ, Wang H, Lu YL, Zhou XL, Chen SW, Chen ZD. Gene transfer of vasoactive intestinal polypeptide into the penis improves erectile response in the diabetic rat. BJU Int 2005; 95: 890-894.
    • (2005) BJU Int , vol.95 , pp. 890-894
    • Shen, Z.J.1    Wang, H.2    Lu, Y.L.3    Zhou, X.L.4    Chen, S.W.5    Chen, Z.D.6
  • 7
    • 0037376430 scopus 로고    scopus 로고
    • The effect of vascular endothelial growth factor and adeno-associated virus mediated brain derived neurotrophic factor on neurogenic and vasculogenic erectile dysfunction induced by hyperlipidemia
    • Gholami SS, Rogers R, Chang J, Ho HC, Grazziottin T, Lin CS et al. The effect of vascular endothelial growth factor and adeno-associated virus mediated brain derived neurotrophic factor on neurogenic and vasculogenic erectile dysfunction induced by hyperlipidemia. J Urol 2003; 169: 1577-1581.
    • (2003) J Urol , vol.169 , pp. 1577-1581
    • Gholami, S.S.1    Rogers, R.2    Chang, J.3    Ho, H.C.4    Grazziottin, T.5    Lin, C.S.6
  • 8
    • 0036085756 scopus 로고    scopus 로고
    • Gene therapy of erectile dysfunction in the rat with penile neuronal nitric oxide synthase
    • Magee TR, Ferrini M, Garban HJ, Vernet D, Mitani K, Rajfer J et al. Gene therapy of erectile dysfunction in the rat with penile neuronal nitric oxide synthase. Biol Reprod 2002; 67: 20-28.
    • (2002) Biol Reprod , vol.67 , pp. 20-28
    • Magee, T.R.1    Ferrini, M.2    Garban, H.J.3    Vernet, D.4    Mitani, K.5    Rajfer, J.6
  • 9
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
    • Boussif O, Lezoualc'h F, Zanta MA, Mergny MD, Scherman D, Demeneix B et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA 1995; 92: 7297-7301.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7297-7301
    • Boussif, O.1    Lezoualc'h, F.2    Zanta, M.A.3    Mergny, M.D.4    Scherman, D.5    Demeneix, B.6
  • 10
    • 22644431808 scopus 로고    scopus 로고
    • Water-soluble lipopolymer as a gene carrier to corpus cavernosum
    • Lee M, Ryu JK, Oh SM, Lee E, Shin HY, Song SU et al. Water-soluble lipopolymer as a gene carrier to corpus cavernosum. Int J Imp Res 2005; 17: 326-334.
    • (2005) Int J Imp Res , vol.17 , pp. 326-334
    • Lee, M.1    Ryu, J.K.2    Oh, S.M.3    Lee, E.4    Shin, H.Y.5    Song, S.U.6
  • 11
    • 3242807724 scopus 로고    scopus 로고
    • Gene transfer with modified polyethylenimines
    • Kichler A. Gene transfer with modified polyethylenimines. J Gene Med 2004; 6: S3-S10.
    • (2004) J Gene Med , vol.6
    • Kichler, A.1
  • 12
    • 33645508745 scopus 로고    scopus 로고
    • Combined angiopoietin-1 and vascular endothelial growth factor gene transfer restores cavernous angiogenesis and erectile function in a rat model of hypercholesterolemia
    • Ryu JK, Cho CH, Shin HY, Song SU, Oh SM, Lee M et al. Combined angiopoietin-1 and vascular endothelial growth factor gene transfer restores cavernous angiogenesis and erectile function in a rat model of hypercholesterolemia. Mol Ther 2006; 13: 705-715.
    • (2006) Mol Ther , vol.13 , pp. 705-715
    • Ryu, J.K.1    Cho, C.H.2    Shin, H.Y.3    Song, S.U.4    Oh, S.M.5    Lee, M.6
  • 13
    • 10344242040 scopus 로고    scopus 로고
    • Vascular endothelial growth factor restores erectile function through inhibition of apoptosis in diabetic rat penile crura
    • Yamanaka M, Shirai M, Shiina H, Tanaka Y, Enokida H, Tsujimura A et al. Vascular endothelial growth factor restores erectile function through inhibition of apoptosis in diabetic rat penile crura. J Urol 2005; 173: 318-323.
    • (2005) J Urol , vol.173 , pp. 318-323
    • Yamanaka, M.1    Shirai, M.2    Shiina, H.3    Tanaka, Y.4    Enokida, H.5    Tsujimura, A.6
  • 14
    • 31744431907 scopus 로고    scopus 로고
    • Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat
    • Shirai M, Yamanaka M, Shiina H, Igawa M, Kawakami T, Ishii N et al. Vascular endothelial growth factor restores erectile function through modulation of the insulin-like growth factor system and sex hormone receptors in diabetic rat. Biochem Biophys Res Commun 2006; 341: 755-762.
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 755-762
    • Shirai, M.1    Yamanaka, M.2    Shiina, H.3    Igawa, M.4    Kawakami, T.5    Ishii, N.6
  • 15
    • 0032557564 scopus 로고    scopus 로고
    • Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
    • Gerber HP, Dixit V, Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 1998; 273: 13313-13316.
    • (1998) J Biol Chem , vol.273 , pp. 13313-13316
    • Gerber, H.P.1    Dixit, V.2    Ferrara, N.3
  • 16
    • 0032963472 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression
    • Nor JE, Christensen J, Mooney DJ, Polverini PJ. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J Pathol 1999; 154: 375-384.
    • (1999) Am J Pathol , vol.154 , pp. 375-384
    • Nor, J.E.1    Christensen, J.2    Mooney, D.J.3    Polverini, P.J.4
  • 17
    • 43649086866 scopus 로고    scopus 로고
    • Koul S, Johnson T, Meacham RB, Koul HK. Cloning and characterization of VEGF from LnCaP cells, a line of prostate cancer cells, LOCUS AY766116, http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nuccore&id=54401694.
    • Koul S, Johnson T, Meacham RB, Koul HK. Cloning and characterization of VEGF from LnCaP cells, a line of prostate cancer cells, LOCUS AY766116, http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nuccore&id=54401694.
  • 19
    • 15944425802 scopus 로고    scopus 로고
    • The effect of PDE5 inhibition on the erectile function in streptozotocin-induced diabetic rats
    • Ahn GJ, Sohn YS, Kang KK, Ahn BO, Kwon JW, Kang SK et al. The effect of PDE5 inhibition on the erectile function in streptozotocin-induced diabetic rats. Int J Imp Res 2005; 17: 134-141.
    • (2005) Int J Imp Res , vol.17 , pp. 134-141
    • Ahn, G.J.1    Sohn, Y.S.2    Kang, K.K.3    Ahn, B.O.4    Kwon, J.W.5    Kang, S.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.