Influence of maternal undernutrition and overfeeding on cardiac ciliary neurotrophic factor receptor and ventricular size in fetal sheep

Journal of Nutritional Biochemistry

Volumn 19, Issue 6, 2008, Pages 409-414

  Dong, Feng ^a   Ford, Stephen P ^a   Nijland, Mark J ^a,b   Nathanielsz, Peter W ^a,b   Ren, Jun ^a  

^a UNIVERSITY OF WYOMING   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

CNTFR; Fetal; Heart; IGF 1; Overnutrition; STAT3; Undernutrition

Indexed keywords

CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA; HYDROCORTISONE; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C RECEPTOR; STAT3 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EWE; FETUS; HEART SIZE; HEART VENTRICLE; HEART WEIGHT; HORMONE BLOOD LEVEL; MALNUTRITION; MATERNAL NUTRITION; MULTIPARA; NONHUMAN; OVERNUTRITION; PREGNANCY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SHEEP; SIGNAL TRANSDUCTION;

ANIMAL NUTRITION PHYSIOLOGY; ANIMALS; CILIARY NEUROTROPHIC FACTOR RECEPTOR ALPHA SUBUNIT; FEMALE; FETUS; HEART VENTRICLES; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; MALNUTRITION; PHOSPHORYLATION; PREGNANCY; PREGNANCY, ANIMAL; RECEPTOR, IGF TYPE 1; RECEPTORS, NERVE GROWTH FACTOR; SHEEP; STAT3 TRANSCRIPTION FACTOR;

OVIS ARIES;

EID: 43649086221     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.06.003     Document Type: Article

References (22)

1. Langley-Evans S.C., Bellinger L., and McMullen S. Animal models of programming: early life influences on appetite and feeding behaviour. Matern Child Nutr 1 3 (2005) 142-148
2. Buckley A.J., Jaquiery A.L., and Harding J.E. Nutritional programming of adult disease. Cell Tissue Res 322 1 (2005) 73-79
3. Moore S.E. Nutrition, immunity and the fetal and infant origins of disease hypothesis in developing countries. Proc Nutr Soc 57 2 (1998) 241-247
4. Wu G., Bazer F.W., Cudd T.A., Meininger C.J., and Spencer T.E. Maternal nutrition and fetal development. J Nutr 134 9 (2004) 2169-2172
5. Yajnik C.S. Obesity epidemic in India: intrauterine origins?. Proc Nutr Soc 63 3 (2004) 387-396
6. Godfrey K., and Robinson S. Maternal nutrition, placental growth and fetal programming. Proc Nutr Soc 57 1 (1998) 105-111
7. Godfrey K.M., and Barker D.J. Fetal nutrition and adult disease. Am J Clin Nutr 71 5 Suppl (2000) 1344S-1352S
8. Barker D.J. Intrauterine programming of coronary heart disease and stroke. Acta Paediatr Suppl 423 (1997) 178-182
9. McMillen I.C., Muhlhausler B.S., Duffield J.A., and Yuen B.S. Prenatal programming of postnatal obesity: fetal nutrition and the regulation of leptin synthesis and secretion before birth. Proc Nutr Soc 63 3 (2004) 405-412
10. Muhlhausler B.S. Programming of the appetite-regulating neural network: a link between maternal overnutrition and the programming of obesity?. J Neuroendocrinol 19 1 (2007) 67-72
11. Schneider H. Ontogenic changes in the nutritive function of the placenta. Placenta 17 1 (1996) 15-26
12. Sleeman M.W., Garcia K., Liu R., Murray J.D., Malinova L., Moncrieffe M., et al. Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice. Proc Natl Acad Sci U S A 100 24 (2003) 14297-14302
13. Elmquist J.K., Elias C.F., and Saper C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22 2 (1999) 221-232
14. Sleeman M.W., Anderson K.D., Lambert P.D., Yancopoulos G.D., and Wiegand S.J. The ciliary neurotrophic factor and its receptor, CNTFR alpha. Pharm Acta Helv 74 2-3 (2000) 265-272
15. Raju S.V., Zheng M., Schuleri K.H., Phan A.C., Bedja D., Saraiva R.M., et al. Activation of the cardiac ciliary neurotrophic factor receptor reverses left ventricular hypertrophy in leptin-deficient and leptin-resistant obesity. Proc Natl Acad Sci U S A 103 11 (2006) 4222-4227
16. Ziotopoulou M., Erani D.M., Hileman S.M., Bjorbaek C., and Mantzoros C.S. Unlike leptin, ciliary neurotrophic factor does not reverse the starvation-induced changes of serum corticosterone and hypothalamic neuropeptide levels but induces expression of hypothalamic inhibitors of leptin signaling. Diabetes 49 11 (2000) 1890-1896
17. Gallaher B.W., Breier B.H., Keven C.L., Harding J.E., and Gluckman P.D. Fetal programming of insulin-like growth factor (IGF)-I and IGF-binding protein-3: evidence for an altered response to undernutrition in late gestation following exposure to periconceptual undernutrition in the sheep. J Endocrinol 159 3 (1998) 501-508
18. Dong F., Ford S.P., Fang C.X., Nijland M.J., Nathanielsz P.W., and Ren J. Maternal nutrient restriction during early to mid gestation up-regulates cardiac insulin-like growth factor (IGF) receptors associated with enlarged ventricular size in fetal sheep. Growth Horm IGF Res 15 4 (2005) 291-299
19. Vonnahme K.A., Hess B.W., Hansen T.R., McCormick R.J., Rule D.C., Moss G.E., et al. Maternal undernutrition from early- to mid-gestation leads to growth retardation, cardiac ventricular hypertrophy, and increased liver weight in the fetal sheep. Biol Reprod 69 1 (2003) 133-140
20. Osgerby J.C., Wathes D.C., Howard D., and Gadd T.S. The effect of maternal undernutrition on ovine fetal growth. J Endocrinol 173 1 (2002) 131-141
21. Takahashi N., Saito Y., Kuwahara K., Harada M., Tanimoto K., Nakagawa Y., et al. Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes. J Mol Cell Cardiol 38 1 (2005) 185-192
22. Ferrazzi E., Bozzo M., Rigano S., Bellotti M., Morabito A., Pardi G., et al. Temporal sequence of abnormal Doppler changes in the peripheral and central circulatory systems of the severely growth-restricted fetus. Ultrasound Obstet Gynecol 19 2 (2002) 140-146