Neurological injury markers in children with septic shock

Pediatric Critical Care Medicine

Volumn 9, Issue 3, 2008, Pages 245-251

  Hsu, Angela A ^a   Fenton, Kimberly ^a,b   Weinstein, Steven ^a   Carpenter, Jessica ^a   Dalton, Heidi ^a   Bell, Michael J ^a  

^a CHILDREN S RESEARCH INSTITUTE   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Glial fibrillary acidic protein; Neurological injury; Neuron specific enolase; Pediatrics; S100 ; Sepsis; Septic shock; Serum markers

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; NEURON SPECIFIC ENOLASE; PROTEIN S100B;

ADOLESCENT; ADULT; ANALYTIC METHOD; ARTICLE; CHILD; CLINICAL ARTICLE; COHORT ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE MARKER; ELECTROENCEPHALOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INFANT; INTENSIVE CARE; NERVOUS SYSTEM INJURY; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEPTIC SHOCK; TERTIARY HEALTH CARE; URINALYSIS;

EID: 43549117058     PISSN: 15297535     EISSN: None     Source Type: Journal    
DOI: 10.1097/PCC.0b013e3181727b22     Document Type: Article

References (50)

1. MC Papadopoulos DC Davies RF Moss Pathophysiology of septic encephalopathy: A review Crit Care Med 28 2000 3019 3024
2. GB Young CF Bolton TW Austin The encephalopathy associated with septic illness Clin Invest Med 13 1990 297 304
3. CF Bolton GB Young DW Zochodne The neurological complications of sepsis Ann Neurol 33 1993 94 100
4. LA Eidelman D Putterman C Putterman The spectrum of septic encephalopathy: Definitions, etiologies, and mortalities JAMA 275 1996 470 473
5. CL Sprung PN Peduzzi CH Shatney Impact of encephalopathy on mortality in the sepsis syndrome. The Veterans Administration Systemic Sepsis Cooperative Study Group Crit Care Med 18 1990 801 806
6. TP Bleck MC Smith SJ Pierre-Louis Neurologic complications of critical medical illnesses Crit Care Med 21 1993 98 103
7. L Hellstrom-Westas Continuous electroencephalography monitoring of the preterm infant Clin Perinatol 33 2006 633 647, vi
8. R Mandel A Martinot F Delepoulle Prediction of outcome after hypoxic-ischemic encephalopathy: A prospective clinical and electrophysiologic study J Pediatr 141 2002 45 50
9. LD Mewasingh C Christophe C Fonteyne Predictive value of electrophysiology in children with hypoxic coma Pediatr Neurol 28 2003 178 183
10. D Murdoch-Eaton M Darowski J Livingston Cerebral function monitoring in paediatric intensive care: Useful features for predicting outcome Dev Med Child Neurol 43 2001 91 96
11. S Bandyopadhyay H Hennes MH Gorelick Serum neuron-specific enolase as a predictor of short-term outcome in children with closed traumatic brain injury Acad Emerg Med 12 2005 732 738
12. RP Berger The use of serum biomarkers to predict outcome after traumatic brain injury in adults and children J Head Trauma Rehabil 21 2006 315 333
13. RP Berger PD Adelson MC Pierce Serum neuron-specific enolase, S100B, and myelin basic protein concentrations after inflicted and noninflicted traumatic brain injury in children J Neurosurg 103 1 Suppl 2005 61 68
14. RP Berger PM Kochanek Urinary S100B concentrations are increased after brain injury in children: A preliminary study Pediatr Crit Care Med 7 2006 557 561
15. RP Berger MC Pierce SR Wisniewski Neuron-specific enolase and S100B in cerebrospinal fluid after severe traumatic brain injury in infants and children Pediatrics 109 2002 E31
16. D Gazzolo E Marinoni R Di Iorio Measurement of urinary S100B protein concentrations for the early identification of brain damage in asphyxiated full-term infants Arch Pediatr Adolesc Med 157 2003 1163 1168
17. KJ Lamers P Vos MM Verbeek Protein S-100B, neuron-specific enolase (NSE), myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and blood of neurological patients Brain Res Bull 61 2003 261 264
18. PE Vos KJ Lamers JC Hendriks Glial and neuronal proteins in serum predict outcome after severe traumatic brain injury Neurology 62 2004 1303 1310
19. FJ Ko CH Chiang CC Wu Studies of neuron-specific enolase levels in serum and cerebrospinal fluid of children with neurological diseases Gaoxiong Yi Xue Ke Xue Za Zhi 6 1990 137 143
20. JE Lima OM Takayanagui LV Garcia Use of neuron-specific enolase for assessing the severity and outcome in patients with neurological disorders Braz J Med Biol Res 37 2004 19 26
21. N Anand LG Stead Neuron-specific enolase as a marker for acute ischemic stroke: A systematic review Cerebrovasc Dis 20 2005 213 219
22. M Herrmann H Ehrenreich Brain derived proteins as markers of acute stroke: Their relation to pathophysiology, outcome prediction and neuroprotective drug monitoring Restor Neurol Neurosci 21 2003 177 190
23. M Oertel U Schumacher DL McArthur S-100B and NSE: Markers of initial impact of subarachnoid haemorrhage and their relation to vasospasm and outcome J Clin Neurosci 13 2006 834 840
24. V Selakovic R Raicevic L Radenovic The increase of neuron-specific enolase in cerebrospinal fluid and plasma as a marker of neuronal damage in patients with acute brain infarction J Clin Neurosci 12 2005 542 547
25. MT Wunderlich H Lins M Skalej Neuron-specific enolase and tau protein as neurobiochemical markers of neuronal damage are related to early clinical course and long-term outcome in acute ischemic stroke Clin Neurol Neurosurg 108 2006 558 563
26. S Di Legge V Di Piero F Di Stani Carotid endarterectomy and gliofibrillar S100b protein release Neurol Sci 24 2003 351 356
27. C Foerch OC Singer T Neumann-Haefelin Evaluation of serum S100B as a surrogate marker for long-term outcome and infarct volume in acute middle cerebral artery infarction Arch Neurol 62 2005 1130 1134
28. Y Tanaka C Koizumi T Marumo Serum S100B indicates brain edema formation and predicts long-term neurological outcomes in rat transient middle cerebral artery occlusion model Brain Res 1137 2007 140 145
29. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis Crit Care Med 20 1992 864 874
30. M Tiainen RO Roine V Pettila Serum neuron-specific enolase and S-100B protein in cardiac arrest patients treated with hypothermia Stroke 34 2003 2881 2886
31. M Dworschak M Franz M Czerny Release of neuron-specific enolase and S100 after implantation of cardioverters/defibrillators Crit Care Med 31 2003 2085 2089
32. RP Berger T Dulani PD Adelson Identification of inflicted traumatic brain injury in well-appearing infants using serum and cerebrospinal markers: A possible screening tool Pediatrics 117 2006 325 332
33. AD Kay A Petzold M Kerr Cerebrospinal fluid apolipoprotein E concentration decreases after traumatic brain injury J Neurotrauma 20 2003 243 250
34. A Petzold G Keir D Lim Cerebrospinal fluid (CSF) and serum S100B: Release and wash-out pattern Brain Res Bull 61 2003 281 285
35. UE Pleines MC Morganti-Kossmann M Rancan S-100 beta reflects the extent of injury and outcome, whereas neuronal specific enolase is a better indicator of neuroinflammation in patients with severe traumatic brain injury J Neurotrauma 18 2001 491 498
36. MS Ali M Harmer R Vaughan Serum S100 protein as a marker of cerebral damage during cardiac surgery Br J Anaesth 85 2000 287 298
37. M Shaaban Ali M Harmer M Elliott A pilot study of evaluation of cerebral function by S100beta protein and near-infrared spectroscopy during cold and warm cardiopulmonary bypass in infants and children undergoing open-heart surgery Anaesthesia 59 2004 20 26
38. K Thorngren-Jerneck C Alling A Herbst S100 protein in serum as a prognostic marker for cerebral injury in term newborn infants with hypoxic ischemic encephalopathy Pediatr Res 55 2004 406 412
39. I Dimopoulou S Korfias U Dafni Protein S-100b serum levels in trauma-induced brain death Neurology 60 2003 947 951
40. LE Pelinka A Kroepfl M Leixnering GFAP versus S100B in serum after traumatic brain injury: Relationship to brain damage and outcome J Neurotrauma 21 2004 1553 1561
41. AA Kanner N Marchi V Fazio Serum S100beta: A noninvasive marker of blood-brain barrier function and brain lesions Cancer 97 2003 2806 2813
42. DN Nguyen H Spapen F Su Elevated serum levels of S-100beta protein and neuron-specific enolase are associated with brain injury in patients with severe sepsis and septic shock Crit Care Med 34 2006 1967 1974
43. A Larsson M Lipcsey J Sjolin Slight increase of serum S-100B during porcine endotoxemic shock may indicate blood-brain barrier damage Anesth Analg 101 2005 1465 1469
44. F Nomura A Koyama M Ishijima Serum levels of five tumor markers for lung cancer in patients with chronic renal failure Oncol Rep 5 1998 389 392
45. B Goldstein B Giroir A Randolph International pediatric sepsis consensus conference: Definitions for sepsis and organ dysfunction in pediatrics Pediatr Crit Care Med 6 2005 2 8
46. R Ramachandrannair R Sharma SK Weiss Reactive EEG patterns in pediatric coma Pediatr Neurol 33 2005 345 349
47. R Ramachandrannair R Sharma SK Weiss A reappraisal of rhythmic coma patterns in children Can J Neurol Sci 32 2005 518 523
48. GB Young CF Bolton YM Archibald The electroencephalogram in sepsis-associated encephalopathy J Clin Neurophysiol 9 1992 145 152
49. C Zauner A Gendo L Kramer Impaired subcortical and cortical sensory evoked potential pathways in septic patients Crit Care Med 30 2002 1136 1139
50. J Unden J Bellner M Eneroth Raised serum S100B levels after acute bone fractures without cerebral injury J Trauma 58 2005 59 61