Percent positive axillary involvement predicts for the development of brain metastasis in high-risk patients with nonmetastatic breast cancer receiving post-mastectomy radiotherapy

Breast Journal

Volumn 14, Issue 3, 2008, Pages 245-249

  Atahan, Ibtisam Lale ^a   Ozyigit, Gokhan ^a   Yildiz, Ferah ^a   Gurkaynak, Murat ^a   Selek, Ugur ^a   Sari, Sait ^a   Hayran, Mutlu ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Brain metastasis; Breast cancer; Radiotherapy

Indexed keywords

CYCLOPHOSPHAMIDE; DOXORUBICIN; ESTROGEN RECEPTOR; FLUOROURACIL; METHOTREXATE;

ADULT; ARTICLE; BRAIN METASTASIS; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER RADIOTHERAPY; CONTROLLED STUDY; FEMALE; HIGH RISK PATIENT; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MASTECTOMY; MULTIPLE CYCLE TREATMENT; POSTOPERATIVE CARE; STATISTICAL ANALYSIS; TUMOR VOLUME;

ADULT; AXILLA; BRAIN NEOPLASMS; BREAST NEOPLASMS; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MASTECTOMY; NEOPLASM STAGING; PREDICTIVE VALUE OF TESTS; RADIOTHERAPY; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 43549111385     PISSN: 1075122X     EISSN: 15244741     Source Type: Journal    
DOI: 10.1111/j.1524-4741.2008.00569.x     Document Type: Article

References (17)

1. Crivellari D, Pagani O, Veronesi A, et al. High incidence of central nervous system involvement in patients with metastatic or locally advanced breast cancer treated with epirubicin and docetaxel. Ann Oncol 2001 12 : 353 6.
2. Ahmann FR, Jones SE, Moon TE. The effect of prior adjuvant chemotherapy on survival in metastatic breast cancer. J Surg Oncol 1988 37 : 116 22.
3. Kosmas C, Malamos NA, Tsavaris NB, et al. Leptomeningeal carcinomatosis after major remission to taxane-based front-line therapy in patients with advanced breast cancer. J Neurooncol 2002 56 : 265 73.
4. Seidman AD, Fornier MN, Esteva FJ, et al. Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification. J Clin Oncol 2001 19 : 2587 95.
5. Tham YL, Sexton K, Kramer R, et al. Primary breast cancer phenotypes associated with propensity for central nervous system metastases. Cancer 2006 107 : 696 704.
6. Gonzalez-Angulo AM, Cristofanilli M, Strom EA, et al. Central nervous system metastases in patients with high-risk breast carcinoma after multimodality treatment. Cancer 2004 101 : 1760 6.
7. Posner JB, Chernik NL. Intracranial metastases from systemic cancer. Adv Neurol 1978 19 : 579 92.
8. Boogerd W, Vos VW, Hart AA, et al. Brain metastases in breast cancer; natural history, prognostic factors and outcome. J Neurooncol 1993 15 : 165 74.
9. DiStefano A, Yong Yap Y, Hortobagyi GN, et al. The natural history of breast cancer patients with brain metastases. Cancer 1979 44 : 1913 8.
10. Tsukada Y, Fouad A, Pickren JW, et al. Central nervous system metastasis from breast carcinoma. Autopsy study. Cancer 1983 52 : 2349 54.
11. Stewart JF, King RJ, Sexton SA, et al. Oestrogen receptors, sites of metastatic disease and survival in recurrent breast cancer. Eur J Cancer 1981 17 : 449 53.
12. Clark GM, Sledge GW Jr., Osborne CK, et al. Survival from first recurrence: relative importance of prognostic factors in 1,015 breast cancer patients. J Clin Oncol 1987 5 : 55 61.
13. Zimm S, Wampler GL, Stablein D, et al. Intracerebral metastases in solid-tumor patients: natural history and results of treatment. Cancer 1981 48 : 384 94.
14. Hagemeister FB Jr., Buzdar AU, Luna MA, et al. Causes of death in breast cancer: a clinicopathologic study. Cancer 1980 46 : 162 7.
15. Chang EL, Lo S. Diagnosis and management of central nervous system metastases from breast cancer. Oncologist 2003 8 : 398 410.
16. Mintz AH, Kestle J, Rathbone MP, et al. A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis. Cancer 1996 78 : 1470 6.
17. Patchell RA, Tibbs PA, Walsh JW, et al. A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 1990 322 : 494 500.