Neanderthal man's MC1R plays fair

Pigment Cell and Melanoma Research

Volumn 21, Issue 3, 2008, Pages 340-341

  Healy, Eugene ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

MELANOCORTIN 1 RECEPTOR;

EVOLUTION; GENE DELETION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC TRANSFECTION; GENETIC VARIABILITY; HUMAN; PHENOTYPE; SHORT SURVEY; SKIN PIGMENTATION;

ANIMALS; EVOLUTION, MOLECULAR; HAIR COLOR; HOMINIDAE; HUMANS; RECEPTOR, MELANOCORTIN, TYPE 1; SKIN PIGMENTATION; SPECIES SPECIFICITY; VARIATION (GENETICS);

HOMO SAPIENS NEANDERTHALENSIS;

EID: 43549109839     PISSN: None     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1755-148X.2008.00465.x     Document Type: Short Survey

References (5)

1. Beaumont, K.A., Newton, R.A., Smit, D.J., Leonard, J.H., Stow, J.L. Sturm, R.A. (2005). Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk. Hum. Mol. Genet. 14, 2145 2154.
2. Healy, E., Jordan, S.A., Budd, P.S., Suffolk, R., Rees, J.L. Jackson, I.J. (2001). Functional variation of MC1R alleles from red-haired individuals. Hum. Mol. Genet. 10, 2397 3402.
3. Lalueza-Fox, C., Römpler, H., Caramelli, D. et al. (2007). A melanocortin 1 receptor allele suggests varying pigmentation among Neanderthals. Science 318, 1453 1455.
4. Lamason, R.L., Mohideen, M.A.P.K., Mest, J.R. et al. (2005). SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans. Science 310, 1782 1786.
5. Miller, C.T., Beleza, S., Pollen, A.A., Schluter, D., Kittles, R.A., Shriver, M.D. Kingsley, D.M. (2007). Cis-regulatory changes in kit ligand expression and parallel evolution of pigmentation in sticklebacks and humans. Cell 131, 1179 1189.