Facile synthesis of orthogonally protected optically pure keto- and diketopiperazine building blocks for combinatorial chemistry

International Journal of Peptide Research and Therapeutics

Volumn 14, Issue 2, 2008, Pages 183-192

  Gellerman, G ^a   Hazan, E ^a,b   Brider, T ^a,b   Traube, T ^a,b   Albeck, A ^b   Shatzmiler, S ^a  

^a ARIEL UNIVERSITY   (Israel)

^b BAR ILAN UNIVERSITY   (Israel)

Author keywords

"Around the scaffold" drug optimization; Boc Fmoc strategy; Combinatorial chemistry; Diketopiperazine; Ketopiperazie; Orthogonal protection; Reductive alkylation; Semi and full orthogonal protection; Solid phase organic chemistry (SPOC)

Indexed keywords

2 KETOPIPERAZINE; 2,5 PIPERAZINEDIONE; 9 FLUORENYLMETHYL CHLOROFORMATE; AMINO ACID; CARBONYL DERIVATIVE; PIPERAZINE DERIVATIVE;

ALKYLATION; ARTICLE; COMBINATORIAL CHEMISTRY; DRUG DESIGN; MEDICINE; SYNTHESIS;

EID: 43549101332     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-008-9129-0     Document Type: Article

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