Ascorbic acid inhibits the migration of walker 256 carcinosarcoma cells

Cellular and Molecular Biology Letters

Volumn 13, Issue 1, 2008, Pages 103-111

  Wybieralska, Ewa ^a   Koza, Monika ^a   Sroka, Jolanta ^a   Czyż, Jarosław ^a   Madeja, Zbigniew ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Ascorbic acid; Cell migration; Metastasis; Reactive oxygen species

Indexed keywords

ASCORBIC ACID; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER CELL; CARCINOSARCOMA; CELL MIGRATION; CELL MOTILITY; CONCENTRATION (PARAMETERS); CORRELATION ANALYSIS; METASTASIS INHIBITION; PHYSIOLOGY;

EID: 43549100214     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-007-0040-z     Document Type: Article

References (25)

1. Cameron, E. and Pauling, L. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer. Proc. Natl. Acad. Sci.73 (1976) 3685–3689.
2. Moertel, C.G., Fleming, T.R., Creagan, E.T., Rubin, J., O’Connell, M.J. and Ames, M.M. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparison. N. Engl. J. Med.312 (1985) 137–141.
3. Naidu, K.A. Vitamin C in human health and disease is still a mystery? An overview. Nutr. J.21 (2003) 2–7.
4. Roomi, M.W., House, D., Eckert-Maksic, M., Maksic, Z.B. and Tsao, C.S. Growth suppression of malignant leukemia cell line in vitro by ascorbic acid (vitamin C) and its derivatives. Cancer Lett.122 (1998) 93–99.
5. Takenaga, M., Igarashi, R., Nakayama, T. and Mizushima, Y. Lecithinized ascorbic acid (PC-AS) effectively inhibits murine pulmonary metastasis. Anticancer Res.19 (1999) 1085–1091.
6. Nagao, N., Nakayama, T., Etoh, T., Saiki, I. and Miwa, N. Tumour invasion is inhibited by phosphorylated ascorbate via enrichment of intracellular vitamin C and decreasing of oxidative stress. J. Cancer Res. Clin. Oncol.126 (2000) 511–518.
7. Taper, H.S., Jamison, J.M., Gilloteaux, J., Summers, J.L. and Calderon, P.B. Inhibition of the development of metastases by dietary vitamin C:K3 combination. Life Sci.75 (2004) 955–967.
8. Liu, J., Zhang, X., Yang, F., Li, T., Wei, D. and Ren, Y. Antimetastatic effect of a lipophilic ascorbic acid derivative with antioxidation through inhibition of tumor invasion. Cancer Chemother. Pharmacol.57 (2006) 584–590.
9. Grimstad, I.A. Direct evidence that cancer cell locomotion contributes importantly to invasion. Exp. Cell. Res.173 (1987) 515–523.
10. Stracke, M.L., Aznavoorian, S.A., Beckner, M.E., Liotta, L.A. and Schiffmann, E. Cell motility, a principal requirement for metastasis. Cell Motility Factors (Goldberg, I.D., Ed.), Birkhauser Verlag, Basel, 1991, 147–162.
11. Padayatty, S.J., Katz, A., Wang, Y., Eck, P., Kwon, O., Lee, J.H., Chen, S., Corpe, C., Dutta, A., Dutta, S.K. and Levine, M. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J. Am. Coll. Nutr.22 (2003) 18–35.
12. Neuzil, J., Thomas, S.R. and Stocker, R. Requirement for, promotion, or inhibition by alpha-tocopherol of radical-induced initiation of plasma lipoprotein lipid peroxidation. Free Radic. Biol. Med.22 (1997) 57–71.
13. Noroozi, M., Angerson, W.J. and Lean, M.E.J. Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes. Am. J. Clin. Nutr.67 (1998) 1210–1218.
14. Liu, J.W., Kayasuga, A., Nagao, N., Masatsuji-Kato, E., Tuzuki, T. and Miwa, N. Repressions of actin assembly and RhoA localization are involved in inhibition of tumor cell motility by lipophilic ascorbyl phosphate. Int. J. Oncol.23 (2003) 1561–1567.
15. Lee, K.W., Lee, H.J., Surh, Y.J. and Lee, C.Y. Vitamin C and cancer chemoprevention: reappraisal. Am. J. Clin. Nutr.78 (2003) 1074–1078.
16. Tanaka, M,. Kogawa, K., Nishihori, Y., Kuribayashi, K., Nakamura, K., Muramatsu, H., Koike, K., Sakamaki, S. and Niitsu, Y. Suppression of intracellular Cu-Zn SOD results in enhanced motility and metastasis of Meth A sarcoma cells. Int. J. Cancer73 (1997) 187–192.
17. Moldovan, L., Moldovan, N.I., Sohn, R.H., Parikh, S.A. and Goldschmidt-Clermont, P.J. Redox changes of cultured endothelial cells and actin dynamics. Circ. Res.86 (2000) 549–557.
18. Sroka, J., Kaminski, R., Michalik, M., Madeja, Z., Przestalski, S. and Korohoda, W. The effect of triethyllead on the motile activity of Walker 256 carcinosarcoma cells. Cell Mol. Biol. Lett.9 (2004) 15–30.
19. Miekus, K., Czernik, M., Sroka, J., Czyz, J. and Madeja, Z. Contact stimulation of prostate cancer cell migration: The role of gap junctional coupling and migration stimulated by heterotypic cell-to-cell contacts in determination of metastatic phenotype of Dunning rat prostate cancer cells. Biol. Cell97 (2005) 893–903.
20. Miekus, K. and Madeja Z. Genistein inhibits the contact-stimulated migration of prostate cancer cells. Cell Mol. Biol. Lett.12 (2007) 348–361.
21. Szydlowska, H., Zaporowska, E., Kuszlik-Jochym, K., Korohoda, W. and Branny, J. Membranolytic activity of detergents as studied with cell viability tests. Folia. Histochem. Cytochem.16 (1978) 69–78.
22. Padayatty, S.J., Sun, H., Wang, Y., Riordan, H.D., Hewitt, S.M., Katz, A., Wesley, R.A. and Levine, M. Vitamin C pharmacokinetics: implications for oral and intravenous use. Ann. Intern. Med. 140 (2004) 533–537.
23. Finkel, T. Oxygen radicals and signaling. Curr. Opin. Cell. Biol.10 (1998) 248–253.
24. Van Wetering, S., van Buul, J.D., Quik, S., Mul, F.P., Anthony, E.C., ten Klooster, J.P., Collard, J.G. and Hordijk, P.L. Reactive oxygen species mediate Rac-induced loss of cell-cell adhesion in primary human endothelial cells. J. Cell. Sci.115 (2002) 1837–1846.
25. Chen, Q., Espey, M.G., Krishna, M.C., Mitchell, J.B., Corpe, C.P., Buettner, G.R., Shacter, E. and Levine, M. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proc. Natl. Acad. Sci.102 (2005) 13604–13609.