메뉴 건너뛰기




Volumn 177, Issue 10, 2006, Pages 6660-6666

Immature CD4+CD8+ thymocytes and mature T cells regulate Nur77 distinctly in response to TCR stimulation

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEAR RECEPTOR NUR77; ORPHAN STEROID RECEPTOR; PROTEIN KINASE B; STEROID RECEPTOR; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 33750825270     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.10.6660     Document Type: Article
Times cited : (46)

References (43)
  • 2
    • 0027957577 scopus 로고
    • + thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28
    • + thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28. J. Exp. Med. 179: 709-713.
    • (1994) J. Exp. Med. , vol.179 , pp. 709-713
    • Punt, J.A.1    Osborne, B.A.2    Takahama, Y.3    Shartow, S.O.4    Singer, A.5
  • 3
    • 0033213877 scopus 로고    scopus 로고
    • Cutting edge: Thymic selection and autoreactivity are regulated by multiple coreceptors involved in T cell activation
    • Page, D. M. 1999. Cutting edge: thymic selection and autoreactivity are regulated by multiple coreceptors involved in T cell activation. J. Immunol. 163: 3577-3581.
    • (1999) J. Immunol. , vol.163 , pp. 3577-3581
    • Page, D.M.1
  • 4
    • 0029831662 scopus 로고    scopus 로고
    • Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes
    • Kishimoto, H., Z. Cai, A. Brunmark, M. R. Jackson, P. A. Peterson, and J. Sprent. 1996. Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes. J. Exp. Med. 184: 531-537.
    • (1996) J. Exp. Med. , vol.184 , pp. 531-537
    • Kishimoto, H.1    Cai, Z.2    Brunmark, A.3    Jackson, M.R.4    Peterson, P.A.5    Sprent, J.6
  • 5
    • 0037459321 scopus 로고    scopus 로고
    • Signaling life and death in the thymus: Timing is everything
    • Werlen, G., B. Hausmann, D. Naeher, and E. Palmer. 2003. Signaling life and death in the thymus: timing is everything. Science 299: 1859-1863.
    • (2003) Science , vol.299 , pp. 1859-1863
    • Werlen, G.1    Hausmann, B.2    Naeher, D.3    Palmer, E.4
  • 6
    • 0028807837 scopus 로고
    • A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection
    • Calnan, B. J., S. Szychowski, F. K. Chan, D. Cado, and A. Winoto. 1995. A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection. Immunity 3: 273-282.
    • (1995) Immunity , vol.3 , pp. 273-282
    • Calnan, B.J.1    Szychowski, S.2    Chan, F.K.3    Cado, D.4    Winoto, A.5
  • 7
    • 0028008513 scopus 로고
    • Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas
    • Woronicz, J. D., B. Calnan, V. Ngo, and A. Winoto. 1994. Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas. Nature 367: 277-281.
    • (1994) Nature , vol.367 , pp. 277-281
    • Woronicz, J.D.1    Calnan, B.2    Ngo, V.3    Winoto, A.4
  • 8
    • 0027976193 scopus 로고
    • Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77
    • Liu, Z. G., S. W. Smith, K. A. McLaughlin, L. M. Schwartz, and B. A. Osborne. 1994. Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. Nature 367: 281-284.
    • (1994) Nature , vol.367 , pp. 281-284
    • Liu, Z.G.1    Smith, S.W.2    McLaughlin, K.A.3    Schwartz, L.M.4    Osborne, B.A.5
  • 9
    • 0029914914 scopus 로고    scopus 로고
    • Inhibition of Nur77/Nurr leads to inefficient clonal deletion of self-reactive T cells
    • Zhou, T., J. Cheng, P. Yang, Z. Wang, C. Liu, X. Su, H. Bluethmann, and J. D. Mountz. 1996. Inhibition of Nur77/Nurr leads to inefficient clonal deletion of self-reactive T cells. J. Exp. Med. 183: 1879-1892.
    • (1996) J. Exp. Med. , vol.183 , pp. 1879-1892
    • Zhou, T.1    Cheng, J.2    Yang, P.3    Wang, Z.4    Liu, C.5    Su, X.6    Bluethmann, H.7    Mountz, J.D.8
  • 12
    • 0025200728 scopus 로고
    • The NGFI-B protein, an inducible member of the thyroid/steroid receptor family, is rapidly modified post-translationally
    • Fahrner, T. J., S. L. Carroll, and J. Milbrandt. 1990. The NGFI-B protein, an inducible member of the thyroid/steroid receptor family, is rapidly modified post-translationally. Mol. Cell. Biol. 10: 6454-6459.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 6454-6459
    • Fahrner, T.J.1    Carroll, S.L.2    Milbrandt, J.3
  • 14
    • 0025729512 scopus 로고
    • Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment
    • Hazel, T. G., R. Misra, I. J. Davis, M. E. Greenberg, and L. F. Lau. 1991. Nur77 is differentially modified in PC12 cells upon membrane depolarization and growth factor treatment. Mol. Cell. Biol. 11: 3239-3246.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3239-3246
    • Hazel, T.G.1    Misra, R.2    Davis, I.J.3    Greenberg, M.E.4    Lau, L.F.5
  • 15
    • 31544443527 scopus 로고    scopus 로고
    • Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation
    • Wingate, A. D., D. G. Campbell, M. Peggie, and J. S. Arthur. 2006. Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation. Biochem. J. 393: 715-724.
    • (2006) Biochem. J. , vol.393 , pp. 715-724
    • Wingate, A.D.1    Campbell, D.G.2    Peggie, M.3    Arthur, J.S.4
  • 17
    • 0035980060 scopus 로고    scopus 로고
    • Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis
    • Masuyama, N., K. Oishi, Y. Mori, T. Ueno, Y. Takahama, and Y. Gotoh. 2001. Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis. J. Biol. Chem. 276: 32799-32805.
    • (2001) J. Biol. Chem. , vol.276 , pp. 32799-32805
    • Masuyama, N.1    Oishi, K.2    Mori, Y.3    Ueno, T.4    Takahama, Y.5    Gotoh, Y.6
  • 19
    • 0027223906 scopus 로고
    • Functional domains and phosphorylation of the orphan receptor Nur77
    • Davis, I. J., T. G. Hazel, R. H. Chen, J. Blenis, and L. F. Lau. 1993. Functional domains and phosphorylation of the orphan receptor Nur77. Mol. Endocrinol. 7: 953-964.
    • (1993) Mol. Endocrinol. , vol.7 , pp. 953-964
    • Davis, I.J.1    Hazel, T.G.2    Chen, R.H.3    Blenis, J.4    Lau, L.F.5
  • 20
    • 0033780029 scopus 로고    scopus 로고
    • Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B
    • Katagiri, Y., K. Takeda, Z. X. Yu, V. J. Ferrans, K. Ozato, and G. Guroff. 2000. Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B. Nat. Cell Biol. 1: 435-440.
    • (2000) Nat. Cell Biol. , vol.1 , pp. 435-440
    • Katagiri, Y.1    Takeda, K.2    Yu, Z.X.3    Ferrans, V.J.4    Ozato, K.5    Guroff, G.6
  • 21
    • 0036291104 scopus 로고    scopus 로고
    • Nuclear receptor and apoptosis initiator NGFI-B is a substrate for kinase ERK2
    • Slagsvold, H. H., A. Ostvold, A. Fallgren, and R. E. Paulsen. 2002. Nuclear receptor and apoptosis initiator NGFI-B is a substrate for kinase ERK2. Biochem. Biophys Res. 291: 1146-1150.
    • (2002) Biochem. Biophys Res. , vol.291 , pp. 1146-1150
    • Slagsvold, H.H.1    Ostvold, A.2    Fallgren, A.3    Paulsen, R.E.4
  • 22
    • 0032723235 scopus 로고    scopus 로고
    • Nur77 transcription activity correlates with its apoptotic function in vivo
    • Kuang, A. A., D. Cado, and A. Winoto. 1999. Nur77 transcription activity correlates with its apoptotic function in vivo. Eur. J. Immunol. 29: 3722-3728.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 3722-3728
    • Kuang, A.A.1    Cado, D.2    Winoto, A.3
  • 24
    • 0037377983 scopus 로고    scopus 로고
    • Ligation of retinoic acid receptor α regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of him
    • Szegezdi, E., I. Kiss, A. Simon, B. Blasko, U. Reichert, S. Michel, M. Sandor, L. Fesus, and Z. Szondy. 2003. Ligation of retinoic acid receptor α regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of him. J. Immunol. 170: 3577-3584.
    • (2003) J. Immunol. , vol.170 , pp. 3577-3584
    • Szegezdi, E.1    Kiss, I.2    Simon, A.3    Blasko, B.4    Reichert, U.5    Michel, S.6    Sandor, M.7    Fesus, L.8    Szondy, Z.9
  • 25
    • 0034682890 scopus 로고    scopus 로고
    • Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3
    • Li, H., S. K. Kolluri, J. Gu, M. I. Dawson, X. Cao, P. D. Hobbs, B. Lin, G. Chen, J. Lu, F. Lin, et al. 2000. Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. Science 289: 1159-1164.
    • (2000) Science , vol.289 , pp. 1159-1164
    • Li, H.1    Kolluri, S.K.2    Gu, J.3    Dawson, M.I.4    Cao, X.5    Hobbs, P.D.6    Lin, B.7    Chen, G.8    Lu, J.9    Lin, F.10
  • 26
    • 0036799150 scopus 로고    scopus 로고
    • Dual roles of Nur77 in selective regulation of apoptosis and cell cycle by TPA and ATRA in gastric cancer cells
    • Wu, Q., S. Liu, X. F. Ye, Z. W. Huang, and W. J. Su. 2002. Dual roles of Nur77 in selective regulation of apoptosis and cell cycle by TPA and ATRA in gastric cancer cells. Carcinogenesis 23: 1583-1592.
    • (2002) Carcinogenesis , vol.23 , pp. 1583-1592
    • Wu, Q.1    Liu, S.2    Ye, X.F.3    Huang, Z.W.4    Su, W.J.5
  • 29
    • 7644221712 scopus 로고    scopus 로고
    • Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting
    • Cao, X., W. Liu, F. Lin, H. Li, S. K. Kolluri, B. Lin, Y. H. Han, M. I. Dawson, and X. K. Zhang. 2004. Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting. Mol. Cell. Biol. 24: 9705-9725.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 9705-9725
    • Cao, X.1    Liu, W.2    Lin, F.3    Li, H.4    Kolluri, S.K.5    Lin, B.6    Han, Y.H.7    Dawson, M.I.8    Zhang, X.K.9
  • 30
    • 1342306819 scopus 로고    scopus 로고
    • Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3
    • Lin, B., S. K. Kolluri, F. Lin, W. Liu, Y. H. Han, X. Cao, M. I. Dawson, J. C. Reed, and X. K. Zhang. 2004. Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3. Cell 116: 527-540.
    • (2004) Cell , vol.116 , pp. 527-540
    • Lin, B.1    Kolluri, S.K.2    Lin, F.3    Liu, W.4    Han, Y.H.5    Cao, X.6    Dawson, M.I.7    Reed, J.C.8    Zhang, X.K.9
  • 32
    • 0023722868 scopus 로고
    • Engagement of the CD4 molecule influences cell surface expression of the T-cell receptor on thymocytes
    • McCarthy, S. A., A. M. Kruisbeek, I. K. Uppenkamp, S. O. Sharrow, and A. Singer. 1988. Engagement of the CD4 molecule influences cell surface expression of the T-cell receptor on thymocytes. Nature 336: 76-79.
    • (1988) Nature , vol.336 , pp. 76-79
    • McCarthy, S.A.1    Kruisbeek, A.M.2    Uppenkamp, I.K.3    Sharrow, S.O.4    Singer, A.5
  • 33
    • 0030993441 scopus 로고    scopus 로고
    • Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals
    • Cibotti, R., J. A. Punt, K. S. Dash, S. O. Sharrow, and A. Singer. 1997. Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals. Immunity 6: 245-255.
    • (1997) Immunity , vol.6 , pp. 245-255
    • Cibotti, R.1    Punt, J.A.2    Dash, K.S.3    Sharrow, S.O.4    Singer, A.5
  • 34
    • 0037453909 scopus 로고    scopus 로고
    • Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells
    • Chun, K. H., J. W. Kosmeder II, S. Sun, J. M. Pezzuto, R. Lotan, W. K. Hong, and H. Y. Lee. 2003. Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells. J. Natl. Cancer Inst. 95:291-302.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 291-302
    • Chun, K.H.1    Kosmeder II, J.W.2    Sun, S.3    Pezzuto, J.M.4    Lotan, R.5    Hong, W.K.6    Lee, H.Y.7
  • 35
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi, D. R., A. Cuenda, P. Cohen, D. T. Dudley, and A. R. Saltiel. 1995. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270: 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 38
    • 33644865025 scopus 로고    scopus 로고
    • 87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function
    • 87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function. J. Biol. Chem. 281: 813-823.
    • (2006) J. Biol. Chem. , vol.281 , pp. 813-823
    • Qi, X.J.1    Wildey, G.M.2    Howe, P.H.3
  • 39
    • 0042847224 scopus 로고    scopus 로고
    • Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation
    • Na, S. Y., A. Patra, Y. Scheuring, A. Marx, M. Tolaini, D. Kioussis, B. A. Hammings, T. Hunig, and U. Bommhardt. 2003. Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation. J. Immunol. 171: 1285-1296.
    • (2003) J. Immunol. , vol.171 , pp. 1285-1296
    • Na, S.Y.1    Patra, A.2    Scheuring, Y.3    Marx, A.4    Tolaini, M.5    Kioussis, D.6    Hammings, B.A.7    Hunig, T.8    Bommhardt, U.9
  • 43
    • 0034669979 scopus 로고    scopus 로고
    • + thymocytes do not polarize lipid rafts in response to TCR-mediated signals
    • + thymocytes do not polarize lipid rafts in response to TCR-mediated signals. J. Immunol. 165: 5435-5442.
    • (2000) J. Immunol. , vol.165 , pp. 5435-5442
    • Ebert, P.J.1    Baker, J.F.2    Punt, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.