An efficient, stereocontrolled synthesis of the 25-(R)-diastereomer of dafchronic acid A from β-ergosterol

Organic Letters

Volumn 10, Issue 5, 2008, Pages 801-802

  Giroux, Simon ^a   Corey, E J ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; DAFACHRONIC ACID A; DRUG DERIVATIVE; ERGOSTEROL; LIGAND;

ANIMAL; ARTICLE; CAENORHABDITIS ELEGANS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENETICS; LONGEVITY; METABOLISM; PHYSIOLOGY; STEREOISOMERISM;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; ERGOSTEROL; LIGANDS; LONGEVITY; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 43549091899     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol702936f     Document Type: Article

References (6)

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2. (b) Gerisch, B.; Rottiers, V.; Li, D.; Motola, D. L.; Cummins, C. L.; Lehrach, H.; Mangelsdorf, D. J.; Antebi, A. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 5014-5019.
3. (c) For an online resource on C. elegans, see: http://www.wormbook.org.
4. Rottiers, V.; Motola, D. L.; Gerisch, B.; Cummins, C. L.; Nishiwaki, K.; Mangelsdorf, D. J.; Antebi, A. Dev. Cell 2006, 10, 473-482.
5. Giroux, S.; Corey, E. J. J. Am. Chem. Soc. 2007, 129, 9866-9867.
6. Zieg1er, F. E. Chem. Rev. 1988, 88, 1423-1452.