Contribution of hydroxymethylbutenyl diphosphate synthase to carotenoid biosynthesis in bacteria and plants

Biochemical and Biophysical Research Communications

Volumn 371, Issue 3, 2008, Pages 510-514

  Flores Pérez, Úrsula ^a,b   Pérez Gil, Jordi ^a,b   Rodríguez Villalón, Antía ^a,b   Gil, María José ^c   Vera, Pablo ^c   Rodríguez Concepción, Manuel ^a,b  

^a CSIC   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c Ciudad Politécnica de la Innovación   (Spain)

Author keywords

Carotenoids; Hydroxymethylbutenyl diphosphate synthase; Isoprenoids; Metabolic engineering; Methylerythritol 4 phosphate pathway

Indexed keywords

CAROTENOID; HYDROXYMETHYLBUTENYL DIPHOSPHATE SYNTHASE; ISOPRENOID; METHYLERYTHRITOL 4 PHOSPHATE; PHOSPHATE; SYNTHETASE;

ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; ENZYME ACTIVITY; ESCHERICHIA COLI; MEASUREMENT; NONHUMAN; PLASTID; PRIORITY JOURNAL; UPREGULATION;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CAROTENOIDS; ENZYMES; ERYTHRITOL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; PLASTIDS; SUGAR PHOSPHATES; UP-REGULATION;

ARABIDOPSIS THALIANA; ESCHERICHIA COLI;

EID: 43549083661     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.04.115     Document Type: Article

References (28)

1. Rodríguez-Concepción M., and Boronat A. Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics. Plant Physiol. 130 (2002) 1079-1089
2. Bouvier F., Rahier A., and Camara B. Biogenesis, molecular regulation and function of plant isoprenoids. Prog. Lipid Res. 44 (2005) 357-429
3. Eisenreich W., Bacher A., Arigoni D., and Rohdich F. Biosynthesis of isoprenoids via the non-mevalonate pathway. Cell. Mol. Life Sci. 61 (2004) 1401-1426
4. Aharoni A., Jongsma M.A., and Bouwmeester H.J. Volatile science? Metabolic engineering of terpenoids in plants. Trends Plant Sci. 10 (2005) 594-602
5. Withers S.T., and Keasling J.D. Biosynthesis and engineering of isoprenoid small molecules. Appl. Microbiol. Biotechnol. 73 (2007) 980-990
6. Rodríguez-Concepción M. Early steps in isoprenoid biosynthesis: Multilevel regulation of the supply of common precursors in plant cells. Phytochem. Rev. 5 (2006) 1-15
7. Rodríguez-Concepción M., Querol J., Lois L.M., Imperial S., and Boronat A. Bioinformatic and molecular analysis of hydroxymethylbutenyl diphosphate synthase (GCPE) gene expression during carotenoid accumulation in ripening tomato fruit. Planta 217 (2003) 476-482
8. Querol J., Campos N., Imperial S., Boronat A., and Rodriguez-Concepcion M. Functional analysis of the Arabidopsis thaliana GCPE protein involved in plastid isoprenoid biosynthesis. FEBS Lett. 514 (2002) 343-346
9. Sauret-Güeto S., Botella-Pavía P., Flores-Pérez U., Martínez-García J.F., San Román C., León P., Boronat A., and Rodriguez-Concepcion M. Plastid cues posttranscriptionally regulate the accumulation of key enzymes of the methylerythritol phosphate pathway in Arabidopsis. Plant Physiol. 141 (2006) 75-84
10. Oudin A., Mahroug S., Courdavault V., Hervouet N., Zelwer C., Rodriguez-Concepcion M., St-Pierre B., and Burlat V. Spatial distribution and hormonal regulation of gene products from methyl erythritol phosphate and monoterpene-secoiridoid pathways in Catharanthus roseus. Plant Mol. Biol. 65 (2007) 13-30
11. Gil M.J., Coego A., Mauch-Mani B., Jordà L., and Vera P. The Arabidopsis csb3 mutant reveals a regulatory link between salicylic acid-mediated disease resistance and the methyl-erythritol 4-phosphate pathway. Plant J. 44 (2005) 155-166
12. Seemann M., Tse Sum Bui B., Wolff M., Miginiac-Maslow M., and Rohmer M. Isoprenoid biosynthesis in plant chloroplasts via the MEP pathway: direct thylakoid/ferredoxin-dependent photoreduction of GcpE/IspG. FEBS Lett. 580 (2006) 1547-1552
13. Sauret-Güeto S., Urós E.M., Ibáñez E., Boronat A., and Rodriguez-Concepcion M. A mutant pyruvate dehydrogenase E1 subunit allows survival of Escherichia coli strains defective in 1-deoxy-d-xylulose 5-phosphate synthase. FEBS Lett. 580 (2006) 736-740
14. Sauret-Güeto S., Ramos-Valdivia A., Ibanez E., Boronat A., and Rodriguez-Concepcion M. Identification of lethal mutations in Escherichia coli genes encoding enzymes of the methylerythritol phosphate pathway. Biochem. Biophys. Res. Commun. 307 (2003) 408-415
15. Cunningham F.X., Chamovitz D., Misawa N., Gantt E., and Hirschberg J. Cloning and functional expression in Escherichia coli of a cyanobacterial gene for lycopene cyclase, the enzyme that catalyzes the biosynthesis of beta-carotene. FEBS Lett. 328 (1993) 130-138
16. Carretero-Paulet L., Cairo A., Botella-Pavia P., Besumbes O., Campos N., Boronat A., and Rodriguez-Concepcion M. Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase. Plant Mol. Biol. 62 (2006) 683-695
17. Yuan L.Z., Rouviere P.E., Larossa R.A., and Suh W. Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli. Metab. Eng. 8 (2006) 79-90
18. Gutierrez-Nava M.L., Gillmor C.S., Jimenez L.F., Guevara-Garcia A., and Leon P. Chloroplast biogenesis genes act cell and noncell autonomously in early chloroplast development. Plant Physiol. 135 (2004) 471-482
19. Ostrovsky D., Diomina G., Lysak E., Matveeva E., Ogrel O., and Trutko S. Effect of oxidative stress on the biosynthesis of 2-C-methyl-d-erythritol-2,4-cyclopyrophosphate and isoprenoids by several bacterial strains. Arch. Microbiol. 171 (1998) 69-72
20. Puan K.J., Wang H., Dairi T., Kuzuyama T., and Morita C.T. fldA is an essential gene required in the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. FEBS Lett. 579 (2005) 3802-3806
21. Araki N., Kusumi K., Masamoto K., Niwa Y., and Iba K. Temperature -sensitive Arabidopsis mutant defective in 1-deoxy-d-xylulose 5-phosphate synthase within the plastid non-mevalonate pathway of isoprenoid biosynthesis. Physiol. Plant 108 (2000) 19-24
22. Crowell D.N., Packard C.E., Pierson C.A., Giner J.L., Downes B.P., and Chary S.N. Identification of an allele of CLA1 associated with variegation in Arabidopsis thaliana. Physiol. Plant 118 (2003) 29-37
23. Seemann M., Wegner P., Schunemann V., Bui B.T., Wolff M., Marquet A., Trautwein A.X., and Rohmer M. Isoprenoid biosynthesis in chloroplasts via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) from Arabidopsis thaliana is a [4Fe-4S] protein. J. Biol. Inorg. Chem. 10 (2005) 131-137
24. Seemann M., Bui B.T., Wolff M., Tritsch D., Campos N., Boronat A., Marquet A., and Rohmer M. Isoprenoid biosynthesis through the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE) is a [4Fe-4S] protein. Angew. Chem. Int. Ed. Engl. 41 (2002) 4337-4339
25. Rohdich F., Zepeck F., Adam P., Hecht S., Kaiser J., Laupitz R., Grawert T., Amslinger S., Eisenreich W., Bacher A., and Arigoni D. The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: studies on the mechanisms of the reactions catalyzed by IspG and IspH protein. Proc. Natl. Acad. Sci. USA 100 (2003) 1586-1591
26. Wolff M., Seemann M., Tse Sum Bui B., Frapart Y., Tritsch D., Estrabot A.G., Rodríguez-Concepción M., Boronat A., Marquet A., and Rohmer M. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: the (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase (LytB/IspH) from Escherichia coli is a [4Fe-4S] protein. FEBS Lett. 541 (2003) 115-120
27. Botella-Pavía P., Besumbes O., Phillips M.A., Carretero-Paulet L., Boronat A., and Rodríguez-Concepción M. Regulation of carotenoid biosynthesis in plants: evidence for a key role of hydroxymethylbutenyl diphosphate reductase in controlling the supply of plastidial isoprenoid precursors. Plant J. 40 (2004) 188-199
28. Cunningham Jr. F.X., Lafond T.P., and Gantt E. Evidence of a role for LytB in the nonmevalonate pathway of isoprenoid biosynthesis. J. Bacteriol. 182 (2000) 5841-5848