Fallopian damage induced by organophosphate insecticide methyl parathion, and protective effect of vitamins E and C on ultrastructural changes in rats

Toxicology and Industrial Health

Volumn 23, Issue 7, 2007, Pages 429-438

  Guney, Mehmet ^a   Oral, Baha ^a   Demirin, Hilmi ^a   Take, Gulnur ^b   Giray, Seren Gulsen ^b   Altuntas, Irfan ^a  

^a SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b GAZI UNIVERSITY   (Turkey)

Author keywords

fallopian tube; histopathology; lipid peroxidation; methyl parathion; vitamin C; vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; MALONALDEHYDE; PARATHION METHYL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPY; FEMALE; HISTOPATHOLOGY; LIPID PEROXIDATION; NONHUMAN; RAT; UTERINE TUBE DISEASE;

ANALYSIS OF VARIANCE; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; ESTROUS CYCLE; FALLOPIAN TUBE DISEASES; FALLOPIAN TUBES; FEMALE; INSECTICIDES; LIPID PEROXIDATION; METHYL PARATHION; RATS; RATS, WISTAR; VITAMIN E;

RATTUS; ZEA MAYS;

EID: 43449139705     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/0748233707076773     Document Type: Article

References (50)

1. Abell, A., Juul, S. and Bonde, J.P. 2000: Time to pregnancy among female greenhouse workers. Scandinavian Journal of Work Environment Health 26, 131—6.
2. Agarwal, A., Gupta, S. and Sharma, R.K. 2005: Role of oxidative stress in female reproduction. Reproductive Biomedicine 11(5), 641—50.
3. Altuntas, I., Delibas, N., Demirci, M., Kilinc, I. and Tamer, N. 2002a: The effects of methidathion on lipid peroxidation and some liver enzyme: role of vitamins E and C. Archives of Toxicology 7, 470—3.
4. Altuntas, I., Delibas, N. and Sutcu, R. 2002b: The effects of organophosphate insecticide methidathion on lipid peroxidation and anti-oxidant enzymes in rat erythrocytes: role of vitamins E and C. Human and Experimental Toxicology 21, 681—5.
5. Arbuckle, T.E., Savitz, D.A., Mery, L.S. and Curtis, K.M. 1999: Exposure to phenoxy herbicides and the risk of spontaneous abortion. Epidemiology 10, 752—60.
6. Aslan, R., Sekeroglu, M.R., Gultekin, F. and Bayiroglu, F. 1997: Blood lipoperoxidationand antioxidant enzymes in healthy individuals: relation to age, sex, habits, lifestyle and environment. Journal of Environmental Science and Health 32(8), 2102—9.
7. Asmathbanu, I. and Kaliwal, B.B. 1997: Temporal effect of methyl parathion on ovarian compensatory hypertrophy, follicular dynamics and estrous cycle in hemicastrated albino rats. Journal of Basic and Clinical Physiolology and Pharmacology 8, 237—54.
8. Bachowski, S., Kolaja, K.L., Xu, Y., Ketcham, C.A., Stevenson, D.E., Walborg, Jr E.F. and Klaunig, JE 1997: Role of oxidative stress in the mechanism of dieldrin's hepatotoxicity. Annals of Clinical and Laboratory Science 27, 196—209.
9. Bagchi, D., Bagchi, M., Hassoun, E.A. and Stohs, S.J. 1995: In vitro and in vivo generation reactive oxygen species, DNA damage and lactate dehydrogenase leakageby selected pesticides. Toxicology 104, 129—40.
10. Baker, H.W.G., Brindl, J., Irvine, D.S. and Aitken, R.J. 1996: Protective effect of antioxidants on the impairment of sperm motility by activated polymorphonuclear leukocytes. Fertility and Sterility 65, 411—9.
11. Berkowitz, G.S., Wetmur, J., Birman-Deych, E. et al. 2004: In utero pesticide exposure, maternal paraoxonase activity, and head circumference. Environmental Health Perspectives 112, 388—91.
12. Bretveld, R.R., Thomas, C.C., Scheepers, P.P., Zielhuis, G.G. and Roeleveld, N.N. 2006: Pesticide exposure: the hormonal function of the female reproductive system disrupted. Reproductive Biolology and Endocrinology 4, 30.
13. Chantelli-Forti, G., Paolini, M. and Hrelia, P. 1993: Multiple end point procedure to evaluate risk from pesticides. Environmental Health Perspectives 101, 15—20.
14. Costa, L.G., Cole, T.B., Vitalone, A. and Furlong, C.E. 2005: Measurement of paraoxanase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clinical Chemical Acta 352(1—2), 37—47.
15. Dhondup, P. and Kaliwal, B.B. 1997: Inhibition of ovarian compensatory hypertrophy by the administration of methyl parathion in hemicastrated albino rats. Reproductive Toxicology 11, 77—84.
16. Donaldson, D., Kiely, T. and Grube, A. 2002: Pesticides industry sales and usage 1998 and 1999 Market estimates. Environmental protection agency, Office of Prevention, Pesticides, and Toxic Substances, Office Pesticide Programs. Washington, DC: USA.
17. Farr, S.L., Cooper, G.S., Cai, J., Savitz, D.A. and Sandler, D.P. 2004: Pesticide use and menstrual cycle characteristics among premenopausal women in the Agricultural Health Study. American Journal of Epidemiology 160, 1194—1204.
18. Fuortes, L., Clark, M.K., Kirchner, H.L. and Smith, E.M. 1997: Association between female infertility and agricultural work history. American Journal of Industrial Medicine 31, 445—51.
19. Greenlee, A.R., Arbuckle, T.E. and Chyou, P.H. 2003: Risk factors for female infertility in an agricultural region. Epidemiology 14,429—436.
20. Gultekin, F., Delibas, N., Yasar, S. and Kilinc, I. 2001: In vivo changes in antioxidant systems and protective role of melatonin and a combination of vitamin C and vitamin E on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats. Archives of Toxicology 75, 88—96.
21. Gultekin, F., Ozturk, M. and Akdogan, M. 2000: The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro). Archives of Toxicology 74, 533—8.
22. Gupta Dasgupta, J., Data, J., Sarkar, A. and Sengupta, D. 1992: Effect of malathionon antioxidant defence system in human fetus—an in vitro study. Indian Journal of Experimental Biology 30, 352—354.
23. Gupta, R.C., Rech, R.H., Lovell, K.L., Welch, F. and Thornburg, J.E. 1985: Brain cholinergic, behavioral, and morphological development in rats exposed in utero to methyl parathion. Toxicology and Applied Pharmacology 77, 405—13.
24. Gupta, R.C., Thornburg, J.F., Stedman, D.B. and Welsch, F. 1984: Effect of subchronic administration of methyl parathion on in vivo protein synthesis in pregnant rats and their conceptuses. Toxicology and Applied Pharmacology 92, 457—68.
25. Harapanhalli, R.S., Yaghmai, V., Giuliani, D., Howell, R.W. and Rao, D.V. 1996: Antioxidant effects of vitamin C in mice following X-irradiation. Research Communuty Molecular Pathology and Pharmacology 94, 271—87.
26. Idrovo, A.J., Sanin, L.H., Cole, D., Chavarro, J., Caceres, H., Narvaez, J. and Restrepo, M. 2005: Time to first pregnancy among women working in agricultural production. International Archives Occupational Environmental Health 78, 493—500.
27. Institoris, L., Papp, A., Siroki, O. and Banerjee, B.D. 2004: Comparative investigation of behavioral, neurotoxicological, and immunotoxicological indices in detection of subacute combined exposure with methyl parathion and propoxur in rats. Ecotoxicology and Environmental Safety 57(3), 270—7.
28. Kalender, S., Ogutcu, A., Uzunhisarcikli, M., Acikgoz, F., Durak, D., Ulusoy, Y. and Kalender, Y. 2005: Diazinon-induced hepatotoxicity and protective effect of vitamin E on some biochemical indices and ultrastructural changes. Toxicology 211, 197—206.
29. Kristensen, P., Irgens, L.M., Andersen, A., Bye, A.S., and Sundheim, L. 1997: Birth defects among offspring of Norwegian farmers, 1967—1991. Epidemiology 8, 537—44.
30. Kousba, A.A., Poet, T.S. and Timchalk, C. 2003: Characterization of the in vitro kinetic interaction of chlorpyrifos-oxon with rat salivary cholinesterase: a potential biomonitoring matrix. Toxicology 188(2/3), 219—32.
31. Levario-Carrillo, M., Olave, M.E., Corral, D.C., Alderete, J.G., Gagioti, S.M. and Bevilacqua, E. 2004: Placental morphology of rats prenatally exposed to methyl parathion. Experimental and Toxicological Pathology 55, 489—96.
32. Li, H. and Zhang, S. 2002: In vitro cytotoxicity of the organophosphorus insecticide methylparathion to FG-9307, the gill cell line of flounder (Paralichthys olivaceus). Cell Biology and Toxicology 18(4), 235—41.
33. Narayana, K., Prashanthi, N., Nayanatara, A., Harish, C., Kumard, H., Abhilash, K.L. and Bairy, K. 2005: Effects of methyl parathion (o,o-dimethyl o-4-nitrophenyl phosphorothioate) on rat sperm morphology and sperm count, but not fertility, are associated with decreased ascorbic acid level in the testis. Mutation Research 588, 28—34.
34. National Center for Environmental Health. 2003: Second National Report on Human Exposure to Environmental Chemicals. Atlanta, GA: Centers for Disease Control and Prevention.
35. Pastore, L.M., Hertz-Picciotto, I. and Beaumont, J.J. 1997: Risk of stillbirth from occupational and residential exposures. Occupational Environmental Medicine 54, 511—8.
36. Ranjbar, A., Pasalar, P. and Abdollahi, M. 2002: Induction of oxidative stres and acetylcholinesterase inhibition in organophosphorous pesticide manufacturingworkers. Human and Experimental Toxicology 21(4), 179— 82.
37. Schettler, T., Solomon, G., Kaplan, J. and Valenti, M. 2003: Generations at Risk: How environmental toxicants may affect reproductive health in California. George Lithograph. Brisbane, CA, USA
38. Sharma, Y., Bashir, S., Irshad, M., Nag, T.C. and Dogra, T.D. 2005: Dimethoate-induced effects on antioxidant status of liver and brain of rats following subchronic exposure. Toxicology 215, 173—81.
39. Smith, E.M., Hammonds-Ehlers, M., Clark, M.K., Kirchner, H.L. and Fuortes, L. 1997: Occupational exposures and risk of female infertility. Journal of Occupational Environmental Medicine 39, 138—47.
40. Sortur, S.M. and Kaliwal, B.B. 1999: Effect of methyl parathion formulation on estrous cycle and reproductive performances in albino rats. Indian Journal of Experimental Biology 37, 176—8.
41. Stoyanovsky, D., Goldman, R., Darrow, R., Organisciak, D. and Kagan, V. 1995: Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with dihydrolipoic acid. Current Eye Research 14, 181—9.
42. Sutcu, R., Altuntas, I., Yıldırım, B., Karahan, N., Demirin, H. and Delibas, N. 2006: The effects of subchronic methidathion toxicity on rat liver: Role of antioxidant vitamins C and E. Cell Biology and Toxicology 22(3), 221—7.
43. Talbot, P. and Riveles, K. 2005: Smoking and reproduction: the oviduct as a target of cigarette smoke. Reproductive Biology and Endocrinology 28, 3—52.
44. WHO. 1993: International Programmme on Chemical Safety, Environmental Health Criteria 145, Methyl Parathion, 1993: 11—236.
45. Whyatt, R.M., Camann, D.E., Kinney, P.L., et al. 2002: Residential pesticide use during pregnancy among a cohort of urban minority women. Environmental Health Perspectives 110, 507—14.
46. Yamano, T., and Morita, S. 1992: Hepatotoxicity of trichlorfon and dichlorvos in isolated rat hepatocytes. Toxicology 76, 69—77.
47. Yavuz, T., Altuntas, I., Delibas, N., Yıldırım, B., Candır, O., Cora, A., Karahan, N., Ibrişim, E. and Kutsal, A. 2004a: Cardiotoxicity in rats induced by methidathion and ameliorating effect of vitamins E and C. Human and Experimental Toxicology 23, 323—9.
48. Yavuz, T., Delibas, N.,Yildirim, B., Altuntas, I., Candır, O., Cora, A., Karahan, N., Ibrişim, E. and Kutsal, A. 2004b: Vascular wall damage in rats induced by methidathion and ameliorating effect of vitamins E and C. Archives of Toxicology 78, 655—9.
49. Yousefpour, M., Bahrami, F., Shahsavan Behboodi, B., Khoshbaten, A. and Asgari, A. 2006: Paraoxon-induced ultrastructural growth changes of rat cultured hippocampal cells inneurobasal/B27. Toxicology 217(2—3), 221—7.
50. Zarrow, M.X., Yochia, J.M. and McCarthy, J.J. 1964: Experimental endocrinology: a source book of basic techniques. New York: Academic Press;, 196, 36.