Modulation of expression of VEGF in cornea by VEGF siRNA after alkali burn in rabbits

Chinese Ophthalmic Research

Volumn 26, Issue 4, 2008, Pages 245-248

  Zhou, Jinzi ^a   Xia, Xiaobo ^a   Xiong, Siqi ^a   Sun, Wei ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Cornea neovascularization; Rabbit; RNA interference; Vascular endothelial growth factor

Indexed keywords

LIPOSOME; MESSENGER RNA; SMALL INTERFERING RNA; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAUSTIC BURN; CONJUNCTIVA; CONTROLLED STUDY; CORNEA; CORNEA NEOVASCULARIZATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; NONHUMAN; PROTEIN EXPRESSION; PROTEOMICS; RABBIT; RECOMBINANT PLASMID; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 43449123677     PISSN: 10030808     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Robinson GS, Pierce EA, Rook SL, et al. Oligodeoxynucleotides inhibit retinal neovascularization in a murine model of proliferative retinopathy [J]. Proc Natl Acad Sci USA,1996,93(10):4851-4856
2. Bainbridge JW, Mistry A, De Alwis M, et al. Inhibition of retinal neovascularization by gene transfer of soluble VEGF receptor sFlt-1[J]. Gene Ther,2002,9(5):320-326
3. Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs[J]. Genes Dev,2001,15(2):188-200
4. Li GY, Fan B, Wu YZ, et al. Inhibition of vascular endothelial growth factor gene expression by T7-siRNAs in cultured human retinal pigment epithelial cells[J]. Chin Med J (English),2005,118(7):567-573
5. Kim B, Tang Q, Biswas PS, et al. Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis[J]. Am J Pathol,2004, 165(6):2177-2185
6. Tolentino MJ, Brucker AJ, Fosnot J, et al. Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in nonhuman primate, laser-induced model of choroidal neovascularization[J]. Retina,2004,24(1):132-138
7. Guan H, Zhou ZC, Wang H, et al. A small interfering RNA targeting vascular endothelial growth factor inhibits Ewing's sarcoma growth in a Xenograft mouse model[J]. Clin Cancer Res,2005,11(7):2662-2669
8. Chinese source
9. Ebrahim S, Peyman GA, Lee PJ. Applications of liposomes in ophthalmology[J]. Surv Ophthalmol,2005,50(2):167-182
10. Dykxhoorn DM, Novina CD, Sharp PA. Killing the messenger: short RNAs that silence gene expression[J]. Nat Rev Mol Cell Biol,2003,4(6): 457-467