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1
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0042662580
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Pulmonary manifestations of sickle cell disease
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Siddiqui AK, Ahmed S. Pulmonary manifestations of sickle cell disease. Postgrad Med J 2003; 79:384-390.
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Postgrad Med J
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Siddiqui, A.K.1
Ahmed, S.2
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2
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0030657413
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Airway hyperreactivity in children with sickle cell disease
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Leong MA, Dampier C, Varlotta L, et al. Airway hyperreactivity in children with sickle cell disease. J Pediatr 1997; 131:278-283.
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J Pediatr
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Leong, M.A.1
Dampier, C.2
Varlotta, L.3
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3
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0035136308
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Prevalence and reversibility of lower airway obstruction in children with sickle cell disease
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Koumbourlis AC, Zar HJ, Hurlet-Jensen A, et al. Prevalence and reversibility of lower airway obstruction in children with sickle cell disease. J Pediatr 2001; 138:188-192.
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J Pediatr
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Koumbourlis, A.C.1
Zar, H.J.2
Hurlet-Jensen, A.3
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4
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33947243337
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Airway hyperresponsiveness and acute chest syndrome in children with sickle cell anemia
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This study assessed airway hyperreactivity by utilizing cold air and exercise challenge tests
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Sylvester KP, Patey RA, Rafferty GF, et al. Airway hyperresponsiveness and acute chest syndrome in children with sickle cell anemia. Pediatr Pulmonol 2007; 42:272-276. This study assessed airway hyperreactivity by utilizing cold air and exercise challenge tests.
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(2007)
Pediatr Pulmonol
, vol.42
, pp. 272-276
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Sylvester, K.P.1
Patey, R.A.2
Rafferty, G.F.3
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5
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36849032859
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Airway hyerreactivity detected by methecholine challenge in children with sickle cell disease
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This was the first published study using methacholine as a direct challenge test to identify airway hyperreactivity in pediatric patients with SCD. There was a high incidence of airway hyperreactivity in children with SCD, regardless of whether they had episodes of ACS
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Ozbek OY, Malbora B, Sen N, et al. Airway hyerreactivity detected by methecholine challenge in children with sickle cell disease. Pediatr Pulmonol 2007; 42:1187-1192. This was the first published study using methacholine as a direct challenge test to identify airway hyperreactivity in pediatric patients with SCD. There was a high incidence of airway hyperreactivity in children with SCD, regardless of whether they had episodes of ACS.
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(2007)
Pediatr Pulmonol
, vol.42
, pp. 1187-1192
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Ozbek, O.Y.1
Malbora, B.2
Sen, N.3
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6
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14944365672
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Asthma in children with sickle cell disease and its association with acute chest syndrome
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Knight-Madden JM, Forrester TS, Lewis NA, et al. Asthma in children with sickle cell disease and its association with acute chest syndrome. Thorax 2005; 60:206-210.
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(2005)
Thorax
, vol.60
, pp. 206-210
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Knight-Madden, J.M.1
Forrester, T.S.2
Lewis, N.A.3
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7
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33747479576
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Boyd JH, Macklin EA, Strunk RC, et al. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood 2006; 108:2923-2927. This prospective infant cohort study, utilizing subjects from the Cooperative Study for Sickle Cell Disease, determined the incidence rates of ACS and painful episodes in children with and without asthma.
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Boyd JH, Macklin EA, Strunk RC, et al. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood 2006; 108:2923-2927. This prospective infant cohort study, utilizing subjects from the Cooperative Study for Sickle Cell Disease, determined the incidence rates of ACS and painful episodes in children with and without asthma.
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8
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34247193669
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Physician-diagnosed asthma and acute chest syndrome: Associations with NOS polymorphisms
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This paper highlights that in patients with sickle cell disease and asthma, there was a high percentage who had experienced an ACS episode. Also, as the number of ACS episodes increased, the percentage of patients with SCD and asthma increased linearly
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Duckworth L, Hsu L, Feng H, et al. Physician-diagnosed asthma and acute chest syndrome: associations with NOS polymorphisms. Pediatr Pulmonol 2007; 42:332-338. This paper highlights that in patients with sickle cell disease and asthma, there was a high percentage who had experienced an ACS episode. Also, as the number of ACS episodes increased, the percentage of patients with SCD and asthma increased linearly.
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(2007)
Pediatr Pulmonol
, vol.42
, pp. 332-338
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Duckworth, L.1
Hsu, L.2
Feng, H.3
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9
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33747478249
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Painful episodes in children with sickle cell disease and asthma are temporally associated with respiratory symptoms
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This cohort study evaluated whether mild respiratory symptoms preceded or occurred simultaneously with painful episodes in children with SCD and asthma compared to children with SCD without asthma
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Glassberg J, Spivey JF, Strunk R. Painful episodes in children with sickle cell disease and asthma are temporally associated with respiratory symptoms. J Pediatr Hematol Oncol 2006; 28:481-485. This cohort study evaluated whether mild respiratory symptoms preceded or occurred simultaneously with painful episodes in children with SCD and asthma compared to children with SCD without asthma.
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(2006)
J Pediatr Hematol Oncol
, vol.28
, pp. 481-485
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Glassberg, J.1
Spivey, J.F.2
Strunk, R.3
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11
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18144410933
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Asthma in the pediatric patient with acute chest syndrome
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Bryant R. Asthma in the pediatric patient with acute chest syndrome. J Pediatr Healthcare 2005; 19:157-162.
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(2005)
J Pediatr Healthcare
, vol.19
, pp. 157-162
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Bryant, R.1
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12
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13844253982
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Asthma is a risk factor for acute chest syndrome and cerebral vascular accidents in children with sickle cell disease
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Nordness ME, Lynn J, Zacharisen MC, et al. Asthma is a risk factor for acute chest syndrome and cerebral vascular accidents in children with sickle cell disease. Clin Mol Allergy 2005; 3:2.
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(2005)
Clin Mol Allergy
, vol.3
, pp. 2
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Nordness, M.E.1
Lynn, J.2
Zacharisen, M.C.3
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13
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0028291736
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Platt OS, Brambilla DJ, Rosse WF, et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med 1994; 330:1639-2164.
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Platt OS, Brambilla DJ, Rosse WF, et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med 1994; 330:1639-2164.
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14
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33846796350
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Sylvester KP, Patey RA, Broughton S, et al. Temporal relationship of asthma to acute chest syndrome in sickle cell disease. Pediatr Pulmonol 2007; 42:103-106. Although the authors did not find a higher prevalence of asthma in their population of children with SCD, they did discover that the diagnosis of asthma preceded the occurrence of the first ACS episode.
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Sylvester KP, Patey RA, Broughton S, et al. Temporal relationship of asthma to acute chest syndrome in sickle cell disease. Pediatr Pulmonol 2007; 42:103-106. Although the authors did not find a higher prevalence of asthma in their population of children with SCD, they did discover that the diagnosis of asthma preceded the occurrence of the first ACS episode.
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15
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0037322102
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Aldehydes and glutathione in exhaled breath condensate of children with asthma exacerbation
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Corradi M, Folesani G, Andreoli R, et al. Aldehydes and glutathione in exhaled breath condensate of children with asthma exacerbation. Am J Respir Crit Care Med 2003; 167:395-399.
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Am J Respir Crit Care Med
, vol.167
, pp. 395-399
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Corradi, M.1
Folesani, G.2
Andreoli, R.3
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16
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0036092277
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Measurement of inflammatory mediators of eosinophils and lymphocytes in blood in acute asthma; serum levels of ECP influence the bronchodilator response
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Di Lorenzo G, Pacor ML, Morici G, et al. Measurement of inflammatory mediators of eosinophils and lymphocytes in blood in acute asthma; serum levels of ECP influence the bronchodilator response. Int Arch Allergy Immunol 2002; 127:308-315.
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(2002)
Int Arch Allergy Immunol
, vol.127
, pp. 308-315
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Di Lorenzo, G.1
Pacor, M.L.2
Morici, G.3
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17
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0032101042
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Whole blood tissue factor procoagulant activity is elevated in patients with sickle cell disease
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Key NS, Slungaard A, Dandelet L, et al. Whole blood tissue factor procoagulant activity is elevated in patients with sickle cell disease. Blood 1998; 91:4216-4223.
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(1998)
Blood
, vol.91
, pp. 4216-4223
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Key, N.S.1
Slungaard, A.2
Dandelet, L.3
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18
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0034533495
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Elevated serum and bronchoalveolar lavage fluid levels of interleukin 8 and granulocyte colony-stimulating factor associated with the acute chest syndrome in patients with sickle cell disease
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Abbound MR, Taylor EC, Habib D, et al. Elevated serum and bronchoalveolar lavage fluid levels of interleukin 8 and granulocyte colony-stimulating factor associated with the acute chest syndrome in patients with sickle cell disease. Br J Haematol 2000; 111:482-490.
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(2000)
Br J Haematol
, vol.111
, pp. 482-490
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Abbound, M.R.1
Taylor, E.C.2
Habib, D.3
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19
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33745953232
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Impact of acute chest syndrome on lung function of children with sickle cell disease
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This prospective study examined pulmonary abnormalities by utilizing pulmonary function testing in children with SCD who have had an episode of ACS requiring a hospitalization compared to children with SCD who have not experienced an ACS episode and hospitalization
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Sylvester KP, Patey RA, Milligan P, et al. Impact of acute chest syndrome on lung function of children with sickle cell disease. J Pediatr 2006; 149:17-22. This prospective study examined pulmonary abnormalities by utilizing pulmonary function testing in children with SCD who have had an episode of ACS requiring a hospitalization compared to children with SCD who have not experienced an ACS episode and hospitalization.
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(2006)
J Pediatr
, vol.149
, pp. 17-22
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Sylvester, K.P.1
Patey, R.A.2
Milligan, P.3
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20
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34249864469
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Koumbourlis AC, Lee DJ, Lee A. Longitudinal changes in lung function and somatic growth in children with sickle cell disease. Pediatr Pulmonol 2007; 42:483-488. This was the first study published describing a retrospective analysis of a longitudinal follow-up of lung function in children and adolescents with SCD. It was concluded that SCD in children is associated with a change in lung function patterns over time with the development of a predominantly obstructive pattern that increases in prevalence over time.
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Koumbourlis AC, Lee DJ, Lee A. Longitudinal changes in lung function and somatic growth in children with sickle cell disease. Pediatr Pulmonol 2007; 42:483-488. This was the first study published describing a retrospective analysis of a longitudinal follow-up of lung function in children and adolescents with SCD. It was concluded that SCD in children is associated with a change in lung function patterns over time with the development of a predominantly obstructive pattern that increases in prevalence over time.
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22
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0031728862
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Pulmonary function in sickle cell disease with or without acute chest syndrome
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Santoli F, Zerah F, Vasile N, et al. Pulmonary function in sickle cell disease with or without acute chest syndrome. Eur Respir J 1998; 12:1124-1129.
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(1998)
Eur Respir J
, vol.12
, pp. 1124-1129
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Santoli, F.1
Zerah, F.2
Vasile, N.3
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23
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0023857266
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Sickle cell chronic lung disease: Prior mortality and the risk of pulmonary failure
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Powers D, Weidman JA, Odom-Maryon T, et al. Sickle cell chronic lung disease: prior mortality and the risk of pulmonary failure. Medicine 1998; 67:66-76.
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(1998)
Medicine
, vol.67
, pp. 66-76
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Powers, D.1
Weidman, J.A.2
Odom-Maryon, T.3
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25
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10744233940
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Pulmonary hypertension as a risk for death in patients with sickle cell disease
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Gladwin MT, Sachdev V, Jison ML, et al. Pulmonary hypertension as a risk for death in patients with sickle cell disease. N Engl J Med 2004; 350:886-895.
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(2004)
N Engl J Med
, vol.350
, pp. 886-895
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Gladwin, M.T.1
Sachdev, V.2
Jison, M.L.3
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26
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34247470728
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Pulmonary hypertension in sickle cell disease: Relevance to children
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This is an excellent review article
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Kato GJ, Onyekwere OC, Gladwin MT. Pulmonary hypertension in sickle cell disease: relevance to children. Pediatr Hematol Oncol 2007; 24:159-170. This is an excellent review article.
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(2007)
Pediatr Hematol Oncol
, vol.24
, pp. 159-170
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Kato, G.J.1
Onyekwere, O.C.2
Gladwin, M.T.3
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27
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33747108253
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Right ventricular and pulmonary function in sickle cell disease patients with pulmonary hypertension
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The authors report diastolic dysfunction in adults with SCD and pulmonary hypertension
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Akgul F, Yalcin F, Babayigit C, et al. Right ventricular and pulmonary function in sickle cell disease patients with pulmonary hypertension. Pediatr Cardiol 2006; 27:440-446. The authors report diastolic dysfunction in adults with SCD and pulmonary hypertension.
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(2006)
Pediatr Cardiol
, vol.27
, pp. 440-446
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Akgul, F.1
Yalcin, F.2
Babayigit, C.3
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28
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33846338501
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Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease
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This studied adults with SCD and pulmonary hypertension. Pulmonary hypertension and diastolic dysfunction contribute independently to mortality, and both risk factors have extremely poor prognosis
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Sachdev V, Machado RF, Shizukuda Y, et al. Diastolic dysfunction is an independent risk factor for death in patients with sickle cell disease. J Am Coll Cardiol 2007; 49:472-479. This studied adults with SCD and pulmonary hypertension. Pulmonary hypertension and diastolic dysfunction contribute independently to mortality, and both risk factors have extremely poor prognosis.
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(2007)
J Am Coll Cardiol
, vol.49
, pp. 472-479
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Sachdev, V.1
Machado, R.F.2
Shizukuda, Y.3
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29
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33845910404
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Severity of pulmonary hypertension during vaso-occlusive pain crisis and exercise in patients with sickle cell disease
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This describes a study in adults with SCD comparing echocardiogram at rest and during VOC, and right heart catheterization at rest and during exercise. The study suggested that a low capacitance limits ability of the pulmonary vasculature to accommodate exercise or VOC
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Machado RF, Kyle Mack A, Martyr S, et al. Severity of pulmonary hypertension during vaso-occlusive pain crisis and exercise in patients with sickle cell disease. Br J Haematol 2006; 136:319-325. This describes a study in adults with SCD comparing echocardiogram at rest and during VOC, and right heart catheterization at rest and during exercise. The study suggested that a low capacitance limits ability of the pulmonary vasculature to accommodate exercise or VOC.
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(2006)
Br J Haematol
, vol.136
, pp. 319-325
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Machado, R.F.1
Kyle Mack, A.2
Martyr, S.3
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30
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38349071895
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Pulmonary hypertension associated with sickle cell disease: Clinical and laboratory endpoints and disease outcomes
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The authors report the results of echocardiographic and catheterization studies, describing prevalence, risk factors, and mortality for pulmonary hypertension in adults with SCD
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De Castro LM, Jonassaint JC, Graham FL, et al. Pulmonary hypertension associated with sickle cell disease: clinical and laboratory endpoints and disease outcomes. Am J Hematol 2007; 83:19-25. The authors report the results of echocardiographic and catheterization studies, describing prevalence, risk factors, and mortality for pulmonary hypertension in adults with SCD.
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(2007)
Am J Hematol
, vol.83
, pp. 19-25
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De Castro, L.M.1
Jonassaint, J.C.2
Graham, F.L.3
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31
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38349016795
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Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease
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The authors compare risk factors for pulmonary hypertension amongst adults with SC and SS disease
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Taylor JG 6th, Ackah D, Cobb C, et al. Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease. Am J Hematol 2007; 83:6-14. The authors compare risk factors for pulmonary hypertension amongst adults with SC and SS disease.
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(2007)
Am J Hematol
, vol.83
, pp. 6-14
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Taylor 6th, J.G.1
Ackah, D.2
Cobb, C.3
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32
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34547394899
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Sickle cell lung disease and sudden death: A retrospective/prospective study of 21 autopsy cases and literature review
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Autopsy findings of patients who died unexpectedly during an admission for VOC describe a high prevalence of pulmonary pathology
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Graham JK, Mosunjac M, Hanzlick RL, et al. Sickle cell lung disease and sudden death: a retrospective/prospective study of 21 autopsy cases and literature review. Am J Forensic Med Pathol 2007; 28:168-172. Autopsy findings of patients who died unexpectedly during an admission for VOC describe a high prevalence of pulmonary pathology.
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(2007)
Am J Forensic Med Pathol
, vol.28
, pp. 168-172
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Graham, J.K.1
Mosunjac, M.2
Hanzlick, R.L.3
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33
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34250160518
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Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension
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A study in adults documented results of cardiac catheterization, echocardiograms, exercise testing, 6-min walk tests, ventilation/perfusion scans and, high resolution CT scans. A distinction is drawn between pulmonary arterial and pulmonary venous hypertension
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Anthi A, Machado RF, Jison ML, et al. Hemodynamic and functional assessment of patients with sickle cell disease and pulmonary hypertension. Am J Respir Crit Care Med 2007; 175:1272-1279. A study in adults documented results of cardiac catheterization, echocardiograms, exercise testing, 6-min walk tests, ventilation/perfusion scans and, high resolution CT scans. A distinction is drawn between pulmonary arterial and pulmonary venous hypertension.
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(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1272-1279
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Anthi, A.1
Machado, R.F.2
Jison, M.L.3
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34
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0242266583
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Hypoxemia in sickle cell disease: Biomarker modulation and relevance to disease pathophysiology
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Setty B, Stuart M, Dampier C, et al. Hypoxemia in sickle cell disease: biomarker modulation and relevance to disease pathophysiology. Lancet 2003; 362:1450-1455.
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(2003)
Lancet
, vol.362
, pp. 1450-1455
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Setty, B.1
Stuart, M.2
Dampier, C.3
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35
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33947605915
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Hemolysis in sickle cell mice cause pulmonary hypertension due to global impairment in nitric oxide bioavailability
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Hsu LL, Champion HC, Campbell-Lee SA, et al. Hemolysis in sickle cell mice cause pulmonary hypertension due to global impairment in nitric oxide bioavailability. Blood 2007; 109:3088-3098.
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(2007)
Blood
, vol.109
, pp. 3088-3098
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Hsu, L.L.1
Champion, H.C.2
Campbell-Lee, S.A.3
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36
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33745952855
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Right ventricular abnormalities in sickle cell anemia: Evidence of a progressive increase in pulmonary vascular resistance
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This retrospective review summarizes echocardiographic findings and prevalence of pulmonary hypertension in children with SCD
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Qureshi N, Joyce JJ, Qi N, Chang RK, et al. Right ventricular abnormalities in sickle cell anemia: evidence of a progressive increase in pulmonary vascular resistance. J Pediatr 2006; 149:23-27. This retrospective review summarizes echocardiographic findings and prevalence of pulmonary hypertension in children with SCD.
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(2006)
J Pediatr
, vol.149
, pp. 23-27
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Qureshi, N.1
Joyce, J.J.2
Qi, N.3
Chang, R.K.4
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37
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34248229822
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High prevalence of pulmonary hypertension in children with sickle cell disease
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The authors summarize echocardiographically derived prevalence of pulmonary hypertension in children
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Nelson SC, Adade BB, McDonough EA, et al. High prevalence of pulmonary hypertension in children with sickle cell disease. J Pediatr Hematol Oncol 2007; 29:334-337. The authors summarize echocardiographically derived prevalence of pulmonary hypertension in children.
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(2007)
J Pediatr Hematol Oncol
, vol.29
, pp. 334-337
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Nelson, S.C.1
Adade, B.B.2
McDonough, E.A.3
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38
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33749998954
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Elevation of tricuspid regurgitation jet velocity, a marker for pulmonary hypertension in children with sickle cell disease
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A retrospective review summarizes prevalence of and risk factors for PH in children with SCD
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Ambrusko SJ, Gunawardena S, Sakara A, et al. Elevation of tricuspid regurgitation jet velocity, a marker for pulmonary hypertension in children with sickle cell disease. Pediatr Blood Cancer 2006; 47:907-913. A retrospective review summarizes prevalence of and risk factors for PH in children with SCD.
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(2006)
Pediatr Blood Cancer
, vol.47
, pp. 907-913
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Ambrusko, S.J.1
Gunawardena, S.2
Sakara, A.3
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39
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40949158038
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Pulmonary hypertension in children and adolescents with sickle cell disease
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A study in children and young adults described echocardiographically derived prevalence and risk factors for mild and moderate pulmonary hypertension
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Onyekwere OC, Campbell A, Teshome M, et al. Pulmonary hypertension in children and adolescents with sickle cell disease. Pediatr Cardiol 2008; 29:309-312. A study in children and young adults described echocardiographically derived prevalence and risk factors for mild and moderate pulmonary hypertension.
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(2008)
Pediatr Cardiol
, vol.29
, pp. 309-312
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Onyekwere, O.C.1
Campbell, A.2
Teshome, M.3
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40
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36849053398
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Clinical differences between children and adults with pulmonary hypertension and sickle cell disease
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The authors compare prevalence of and risk factors for pulmonary hypertension in adults and children with SCD. Different age-specific mechanisms may be operative
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Hagar RW, Michlitsch JG, Gardner J, et al. Clinical differences between children and adults with pulmonary hypertension and sickle cell disease. Br J Haematol 2008; 140:104-112. The authors compare prevalence of and risk factors for pulmonary hypertension in adults and children with SCD. Different age-specific mechanisms may be operative.
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(2008)
Br J Haematol
, vol.140
, pp. 104-112
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Hagar, R.W.1
Michlitsch, J.G.2
Gardner, J.3
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41
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34548821573
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Platelet activation in patients with sickle cell disease, hemolysis associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin
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This mechanistic article emphasizes the role of platelets and reduced nitric oxide in the genesis of pulmonary hypertension in SCD
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Villagra J, Shiva S, Hunter LA, et al. Platelet activation in patients with sickle cell disease, hemolysis associated pulmonary hypertension, and nitric oxide scavenging by cell-free hemoglobin. Blood 2007; 110:2166-2172. This mechanistic article emphasizes the role of platelets and reduced nitric oxide in the genesis of pulmonary hypertension in SCD.
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(2007)
Blood
, vol.110
, pp. 2166-2172
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Villagra, J.1
Shiva, S.2
Hunter, L.A.3
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42
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24944476691
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Sildenafil therapy in patients with sickle cell disease and pulmonary hypertension
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Machado RF, Martyr S, Kato GJ, et al. Sildenafil therapy in patients with sickle cell disease and pulmonary hypertension. Br J Haematol 2005; 130:445-453.
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(2005)
Br J Haematol
, vol.130
, pp. 445-453
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Machado, R.F.1
Martyr, S.2
Kato, G.J.3
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43
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0043204998
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Arginine therapy: A new treatment for pulmonary hypertension in sickle cell disease?
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Morris CR, Morris SM, Hagar W, et al. Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Am J Respir Crit Care Med 2003; 168:63-69.
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(2003)
Am J Respir Crit Care Med
, vol.168
, pp. 63-69
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Morris, C.R.1
Morris, S.M.2
Hagar, W.3
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44
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1342289333
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Vichinski EP. Pulmonary hypertension in sickle cell disease. N Engl J Med 2004; 350:857-859.
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N Engl J Med
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, pp. 857-859
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Vichinski, E.P.1
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45
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0035402127
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Marcus CL. Sleep-disordered breathing in children. Am J Respir Crit Care Med 2001; 164:16-30.
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Am J Respir Crit Care Med
, vol.164
, pp. 16-30
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Marcus, C.L.1
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46
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0346189939
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Technical report: Diagnosis and management of childhood obstructive sleep apnea syndrome
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American Academy of Pediatrics
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American Academy of Pediatrics. Technical report: Diagnosis and management of childhood obstructive sleep apnea syndrome. Pediatrics 2002; 109:704-712.
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(2002)
Pediatrics
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, pp. 704-712
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47
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37549001373
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O2 ≤94% is a reasonable threshold to recommend a full pulmonary evaluation including a PSG to screen for sleep disordered breathing in children with SCD.
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O2 ≤94% is a reasonable threshold to recommend a full pulmonary evaluation including a PSG to screen for sleep disordered breathing in children with SCD.
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48
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0026720805
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Sleep related upper airway obstruction and hypoxaemia in sickle cell disease
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Samuels MP, Stebbens VA, Davies SC, et al. Sleep related upper airway obstruction and hypoxaemia in sickle cell disease. Arch Dis Child 1992; 67:925-929.
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Arch Dis Child
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Samuels, M.P.1
Stebbens, V.A.2
Davies, S.C.3
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49
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31044445829
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Jacob E, Miaskowski C, Savedra M, et al. Changes in sleep, food intake, and activity levels during acute painful episodes in children with sickle cell disease. J Pediatr Nurs 2006; 21:23-34. This paper evaluated the perception of the amount of sleep children with SCD had during the day and night when they were experiencing pain from a VOC. An increased amount of daily pain was related to poor sleep quality during the night and scores on the amount of sleep was negatively correlated with pain intensity scores.
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Jacob E, Miaskowski C, Savedra M, et al. Changes in sleep, food intake, and activity levels during acute painful episodes in children with sickle cell disease. J Pediatr Nurs 2006; 21:23-34. This paper evaluated the perception of the amount of sleep children with SCD had during the day and night when they were experiencing pain from a VOC. An increased amount of daily pain was related to poor sleep quality during the night and scores on the amount of sleep was negatively correlated with pain intensity scores.
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50
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34547653754
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Brief report: Sleep in children with sickle cell disease: an alalysis of daily diaries utilizing multilevel modes
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This is an informative paper using daily diary data in children with SCD who suffer with chronic pain, highlighting the temporal patterns of sleep and pain. High daily pain was related to poor sleep quality at night and poor sleep quality was related to high SCD pain the following day
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Valrie CR, Gil KM, Redding-Lallinger R, et al. Brief report: sleep in children with sickle cell disease: an alalysis of daily diaries utilizing multilevel modes. J Pediatr Psychol 2007; 32:857-861. This is an informative paper using daily diary data in children with SCD who suffer with chronic pain, highlighting the temporal patterns of sleep and pain. High daily pain was related to poor sleep quality at night and poor sleep quality was related to high SCD pain the following day.
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(2007)
J Pediatr Psychol
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Valrie, C.R.1
Gil, K.M.2
Redding-Lallinger, R.3
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51
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0028905641
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Home management of sickle cell-related pain in children and adolescents: Natural history and impact on school attendance
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Shapiro BS, Dinges DF, Orne EC, et al. Home management of sickle cell-related pain in children and adolescents: Natural history and impact on school attendance. Pain 1995; 61:139-144.
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Shapiro, B.S.1
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52
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How pain and analgesics disturb sleep
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Onen SH, Onen F, Courpron P, et al. How pain and analgesics disturb sleep. Clin J Pain 2005; 21:422-431.
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Clin J Pain
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Onen, S.H.1
Onen, F.2
Courpron, P.3
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53
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Nocturnal oxygen saturation and painful sickle cell crises in children
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Hargrave DR, Wade A, Evans JPM, et al. Nocturnal oxygen saturation and painful sickle cell crises in children. Blood 2003; 101:846-848.
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Hargrave, D.R.1
Wade, A.2
Evans, J.P.M.3
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54
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Mechanisms of nocturnal oxyhemoglobin desaturation in children and adolescents with sickle cell disease
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Needleman JP, Franco ME, Varlotta L, et al. Mechanisms of nocturnal oxyhemoglobin desaturation in children and adolescents with sickle cell disease. Pediatr Pulmonol 1999; 28:418-422.
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Needleman, J.P.1
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Varlotta, L.3
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57
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Does sleep-disordered breathing contribute to the clinical severity of sickle cell anemia?
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Brooks LJ, Koziol SM, Chiarucci KM, et al. Does sleep-disordered breathing contribute to the clinical severity of sickle cell anemia? J Pediatr Hematol Oncol 1996; 18:135-139.
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Koziol, S.M.2
Chiarucci, K.M.3
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58
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Nocturnal hypoxemia and central-nervous-system events in sickle-cell disease
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Kirkham FJ, Hewes DKM, Prengler M, et al. Nocturnal hypoxemia and central-nervous-system events in sickle-cell disease. Lancet 2001; 357:1656-1659.
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Kirkham, F.J.1
Hewes, D.K.M.2
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59
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Exacerbations of sickle cell disease by obstructive sleep apnea
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Sidman JD, Fry TL. Exacerbations of sickle cell disease by obstructive sleep apnea. Arch Otolaryngol Head Neck Surg 1988; 114:916-917.
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Kemp JS. Obstructive sleep apnea and sickle cell disease. J Pediatr Hematol Oncol 1996; 18:104-105.
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Hill CM, Hogan AM, Onugha N, et al. Increased cerebral blood flow velocity in children with mild sleep-disordered breathing: a possible association with abnormal neuropsychological function. Pediatrics 2006; 118:e1100-e1108. This paper describes a relationship between increased cerebral blood flow velocities and upper airway obstruction and the authors concluded that upper airway obstruction should be ruled out in children with abnormal transcranial doppler findings before starting transfusion regimens.
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Hill CM, Hogan AM, Onugha N, et al. Increased cerebral blood flow velocity in children with mild sleep-disordered breathing: a possible association with abnormal neuropsychological function. Pediatrics 2006; 118:e1100-e1108. This paper describes a relationship between increased cerebral blood flow velocities and upper airway obstruction and the authors concluded that upper airway obstruction should be ruled out in children with abnormal transcranial doppler findings before starting transfusion regimens.
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62
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Increased cerebral blood flow velocity in children with sickle cell disease: Adenotonsillectomy or transfusion regimens?
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This editorial to the article by Hill et al, 61••] discusses the cases of two boys with SCD who had abnormally high CBFV and history of snoring and adenotonsillar hypertrophy with a resultant decreased CBVF after an adenoidectomy and/or tonsillectomy
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Bader-Meunier B, Francois M, Verlhac S, et al. Increased cerebral blood flow velocity in children with sickle cell disease: adenotonsillectomy or transfusion regimens? Pediatrics 2007; 120:235-236. This editorial to the article by Hill et al. [61••] discusses the cases of two boys with SCD who had abnormally high CBFV and history of snoring and adenotonsillar hypertrophy with a resultant decreased CBVF after an adenoidectomy and/or tonsillectomy.
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(2007)
Pediatrics
, vol.120
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Bader-Meunier, B.1
Francois, M.2
Verlhac, S.3
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