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Volumn 20, Issue 3, 2008, Pages 279-287

Pulmonary complications of sickle cell disease in children

Author keywords

Asthma; Pulmonary hypertension; Sickle cell disease; Sleep disordered breathing

Indexed keywords

ARGININE; BOSENTAN; HYDROXYUREA; PROSTACYCLIN; SILDENAFIL;

EID: 43449122470     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOP.0b013e3282ff62c4     Document Type: Review
Times cited : (39)

References (62)
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    • Duckworth L, Hsu L, Feng H, et al. Physician-diagnosed asthma and acute chest syndrome: associations with NOS polymorphisms. Pediatr Pulmonol 2007; 42:332-338. This paper highlights that in patients with sickle cell disease and asthma, there was a high percentage who had experienced an ACS episode. Also, as the number of ACS episodes increased, the percentage of patients with SCD and asthma increased linearly.
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    • Glassberg J, Spivey JF, Strunk R. Painful episodes in children with sickle cell disease and asthma are temporally associated with respiratory symptoms. J Pediatr Hematol Oncol 2006; 28:481-485. This cohort study evaluated whether mild respiratory symptoms preceded or occurred simultaneously with painful episodes in children with SCD and asthma compared to children with SCD without asthma.
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    • This mechanistic article emphasizes the role of platelets and reduced nitric oxide in the genesis of pulmonary hypertension in SCD
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    • Hill CM, Hogan AM, Onugha N, et al. Increased cerebral blood flow velocity in children with mild sleep-disordered breathing: a possible association with abnormal neuropsychological function. Pediatrics 2006; 118:e1100-e1108. This paper describes a relationship between increased cerebral blood flow velocities and upper airway obstruction and the authors concluded that upper airway obstruction should be ruled out in children with abnormal transcranial doppler findings before starting transfusion regimens.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.