Molecular Mechanism of ADP-Ribose Hydrolysis By Human NUDT5 From Structural and Kinetic Studies

Journal of Molecular Biology

Volumn 379, Issue 3, 2008, Pages 568-578

  Zha, Manwu ^a   Guo, Qing ^a   Zhang, Yichun ^b   Yu, Biao ^b   Ou, Ying ^a   Zhong, Chen ^a   Ding, Jianping ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

ADP ribose pyrophosphatase; ADPR; molecular mechanism; Nudix domain; NUDT5

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE PHOSPHATE; ALPHA,BETA METHYLENEADENOSINE DIPHOSPHORIBOSE; ARGININE; GLUTAMIC ACID; INORGANIC PYROPHOSPHATASE; MAGNESIUM ION; NUDIX HYDROLASE; PROTEIN NUDT5; RIBOSE PHOSPHATE; TRYPTOPHAN; WATER;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ENZYME MECHANISM; HYDROLYSIS; MOLECULAR MECHANICS; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE;

EID: 43449120696     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.04.006     Document Type: Article

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