Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71

Circulation

Volumn 117, Issue 19, 2008, Pages 2437-2448

  Urasawa, Nobuyuki ^a   Wada, Michiko R ^a   Machida, Noboru ^b   Yuasa, Katsutoshi ^a   Shimatsu, Yoshiki ^a   Wakao, Yoshito ^c   Yuasa, Shigeki ^a   Sano, Toshiaki ^d   Nonaka, Ikuya ^e   Nakamura, Akinori ^a   Takeda, Shin'ichi ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^c AZABU UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKUSHIMA   (Japan)

^e NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

Author keywords

Cardiomyopathy; Conduction; Dystrophin; Purkinje fibers; Utrophin

Indexed keywords

ALPHA SARCOGLYCAN; BETA DYSTROGLYCAN; BETA SARCOGLYCAN; CALPAIN 1; DELTA SARCOGLYCAN; DESMIN; DP71 PROTEIN; DYSTROPHIN; GAMMA SARCOGLYCAN; PROTEIN DERIVATIVE; TROPONIN I; TROPONIN T; UTROPHIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; DISEASE COURSE; DOG; DUCHENNE MUSCULAR DYSTROPHY; HEART CONTRACTION; HEART MUSCLE CONDUCTION SYSTEM; HEART VENTRICLE WALL; IMMUNOBLOTTING; JAPAN; MICRODISSECTION; MUSCLE ATROPHY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PURKINJE FIBER; SARCOLEMMA; UPREGULATION; X CHROMOSOME LINKED DISORDER;

ANIMALS; ARRHYTHMIAS, CARDIAC; DOGS; DYSTROPHIN; DYSTROPHIN-ASSOCIATED PROTEINS; ELECTROCARDIOGRAPHY; MUSCULAR DYSTROPHY, ANIMAL; PURKINJE FIBERS; UP-REGULATION; UTROPHIN; VACUOLES;

EID: 43449114823     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.107.739326     Document Type: Article

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