Extracellular pH defense against lactic acid in untrained and trained altitude residents

European Journal of Applied Physiology

Volumn 103, Issue 2, 2008, Pages 127-137

  Böning, Dieter ^a   Rojas, J ^b   Serrato, M ^c   Reyes, O ^c   Coy, L ^b   Mora, M ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSIDAD NACIONAL DE COLOMBIA   (Colombia)

^c Centro de Servicios Biomedicos   (Colombia)

Author keywords

Base excess; Buffers; Exercise; Hypoxia

Indexed keywords

BICARBONATE; CARBON DIOXIDE; HEMOGLOBIN; LACTIC ACID; PHOSPHATE;

ACID BASE BALANCE; ACIDOSIS; ADULT; ALKALOSIS; ALTITUDE; ARTICLE; BICYCLE ERGOMETER; BLOOD SAMPLING; CARBON DIOXIDE BLOOD LEVEL; CARBON DIOXIDE TENSION; CONTROLLED STUDY; EAR LOBE; ENDURANCE; EXHAUSTION; EXTRACELLULAR FLUID; HEMATOCRIT; HUMAN; HUMAN EXPERIMENT; HYPERVENTILATION; INTERSTITIAL FLUID; LACTATE BLOOD LEVEL; MALE; PH MEASUREMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RESIDENTIAL AREA;

ACCLIMATIZATION; ACID-BASE EQUILIBRIUM; ACIDOSIS, LACTIC; ADAPTATION, PHYSIOLOGICAL; ADULT; ALTITUDE; ANOXIA; BICARBONATES; BUFFERS; COLOMBIA; EXTRACELLULAR FLUID; HEMATOCRIT; HEMOGLOBINS; HUMANS; HYDROGEN-ION CONCENTRATION; HYPERVENTILATION; LACTIC ACID; MALE; MUSCLE CONTRACTION; MUSCLE, SKELETAL; PHYSICAL ENDURANCE; TIME FACTORS;

EID: 43449114198     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-008-0675-0     Document Type: Article

References (26)

1. Bangsbo J, Juel C, Hellsten Y, Saltin B (1997) Dissociation between lactate and proton exchange in muscle during intense exercise in man. J Physiol 504:489-499
2. 2-equilibration curves of blood during acute hypercapnia and hypocapnia. II. Theoretical considerations. Pflügers Arch 350:213-222
3. Böning D, Trost F, Braumann K-M, Bitter H, Bender K, v. z. Mühlen A, Schweigart U (1980) Altitude acclimatization in skiing lowlanders. Int J Sports Med 1:191-198
4. Böning D, Maassen N, Steinacker JM, Seifert C, Thomas A, Schmidt W (1999) Carbon dioxide storage and nonbicarbonate buffering in the human body before and after an Himalayan expedition. Eur J Appl Physiol 79:457-466
5. Böning D, Maassen N, Thomas A, Steinacker JM (2001a) Extracellular pH defense against lactic acid in normoxia and hypoxia before and after a Himalayan expedition. Eur J Appl Physiol 84:78-86
6. Böning D, Rojas J, Serrato M, Ulloa C, Coy L, Mora M, Gomez J, Hütler M (2001b) Hemoglobin mass and peak oxygen uptake in untrained and trained residents of moderate altitude. Int J Sports Med 22:572-578
7. Böning D, Klarholz C, Himmelsbach B, Hütler M, Maassen N (2007a) Causes of differences in exercise-induced changes of base excess and blood lactate. Eur J Appl Physiol 99:163-171
8. Böning D, Klarholz C, Himmelsbach B, Hütler M, Maassen N (2007b) Extracellular bicarbonate and non-bicarbonate buffering against lactic acid during and after exercise. Eur J Appl Physiol 100:457-467
9. Cerretelli P, Samaja M (2003) Acid-base balance at exercise in normoxia and in chronic hypoxia. Revisiting the "lactate paradox". Eur J Appl Physiol 90:431-448
10. Christiansen TF (1981) An algorithm for calculating the concentration of the base excess of blood. In: Siggaard-Andersen O (ed) Proceedings of the IFCC Expert Panel on pH and blood gases held at Herved Hospital 1980. Radiometer A/S, Copenhagen, pp 77-81
11. Favier R et al (1995) Training in hypoxia vs. training in normoxia in high-altitude natives J Appl Physiol 78:2286-2293
12. Gregersen MI, Rawson RA (1959) Blood volume. Physiol Rev 39:307-342
13. 4. J Nutr 129:722-727
14. Jain SC, Bardhan J, Swamy YV, Krishna B, Nayar HS (1980) Body fluid compartments in humans during acute high-altitude exposure. Aviat Space Environ Med 51:234-236
15. Juel C, Lundby C, Sander M, Calbet JA, Hall G (2003) Human skeletal muscle and erythrocyte proteins involved in acid-base homeostasis: adaptations to chronic hypoxia. J Physiol 548:639-648
16. + release from human skeletal muscle. Am J Physiol Endocrinol Metab 286:E245-E251
17. Lang W, Zander R (2005) Prediction of dilutional acidosis based on the revised classical dilution concept for bicarbonate. J Appl Physiol 98:62-71
18. Lundvall J, Mellander S, Westling H, White T (1972) Fluid transfer between blood and tissues during exercise. Acta Physiol Scand 85:258-269
19. Malapartida M, Moncloa F (1967) Radiosulfate space in humans at high altitude. Proc Soc Exp Biol Med 125:1328-1330
20. Milledge JS (1992) Salt and water control at altitude. Int J Sports Med 13:S61-S63
21. Ramirez G, Pineda D, Bittle PA, Rabb H, Rosen R, Vesely D, Sasaki S (1998) Partial renal resistance to arginine vasopressin as an adaptation to high altitude living. Aviat Space Environ Med 69:58-65
22. Robinson Y, Cristancho E, Böning D (2007) Erythrocyte aspartate aminotransferase as an indirect marker for stimulated erythropoiesis in athletes. Lab Hematol 13:49-55
23. 2 stores during incremental exercise. Eur J Appl Physiol 93:555-568
24. Schmidt W, Rojas J, Böning D, Bernal H, Garcia S, Garcia O (1999) Plasma electrolytes in natives to hypoxia after marathon races at different altitudes. Med Sci Sports Exerc 31:1406-1413
25. Siggaard-Andersen O (1974) The acid-base status of the blood. Munksgaard, Copenhagen
26. Wagner PD et al (2001) Pulmonary gas exchange and acid-base state at 5,260 m in high-altitude Bolivians and acclimatized lowlanders. J Appl Physiol 92:1393-1400