Antimicrobial effects of the saliva substitute, Oralbalance®, against microorganisms from oral mucosa in the hematopoietic cell transplantation period

Supportive Care in Cancer

Volumn 16, Issue 4, 2008, Pages 421-424

  Sugiura, Yuko ^a   Soga, Yoshihiko ^a   Tanimoto, Ichiro ^a   Kokeguchi, Susumu ^a   Nishide, Sachiko ^b,d   Kono, Kotoe ^b   Takahashi, Kanayo ^b   Fujii, Nobuharu ^a   Ishimaru, Fumihiko ^a,e   Tanimoto, Mitsune ^a   Yamabe, Kokoro ^a   Tsutani, Soichiro ^a,f   Nishimura, Fusanori ^a,c   Takashiba, Shogo ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY HOSPITAL   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

^d KAGAWA UNIVERSITY HOSPITAL   (Japan)

^e Okayama Red Cross Blood Center   (Japan)

^f Private Dental Office   (Japan)

Author keywords

Antimicrobial activity; Hematopoietic cell transplantation; Saliva substitute; Xerostomia

Indexed keywords

ORALBALANCE; SALIVA SUBSTITUTE;

ADULT; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; BACTERIUM; CANDIDA ALBICANS; CLINICAL ARTICLE; COAGULASE NEGATIVE STAPHYLOCOCCUS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG SENSITIVITY; FEMALE; FUNGUS; FUNGUS GROWTH; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; IMMUNOCOMPROMISED PATIENT; IN VITRO STUDY; INCUBATION TIME; MALE; MICROBIAL IDENTIFICATION; MOUTH FLORA; MOUTH INFECTION; MOUTH MUCOSA; MYCOSIS; NONHUMAN; PRIORITY JOURNAL; XEROSTOMIA;

ADULT; BACTERIA; FEMALE; FUNGI; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; MIDDLE AGED; MOUTH; MOUTH MUCOSA; SALIVA, ARTIFICIAL;

EID: 43449105914     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00520-007-0391-z     Document Type: Article

References (9)

1. Brandtzaeg P (1989) Salivary immunoglobulins. In: Tenovuo J (ed) Human saliva: clinical chemistry and microbiology, vol. II. CRC, Boca Raton, pp 1-54
2. Fanourgiakis P, Georgala A, Vekemans M, Daneau D, Heymans C, Aoun M (2003) Bacteremia due to Stomatococcus mucilaginosus in neutropenic patients in the setting of a cancer institute. Clin Microbiol Infect 9:1068-1072
3. Gruson D, Hilbert G, Pigneux A, Vargas F, Guisset O, Texier J, Boiron JM, Reiffers J, Gbikpi-Benissan G, Cardinaud JP (1998) Severe infection caused by Stomatococcus mucilaginosus in a neutropenic patient: case report and review of the literature. Hematol Cell Ther 40:167-169
4. Kennedy HF, Morrison D, Kaufmann ME, Jackson MS, Bagg J, Gibson BE, Gemmell CG, Michie JR (2000) Origins of Staphylococcus epidermidis and Streptococcus oralis causing bacteraemia in a bone marrow transplant patient. J Med Microbiol 49:367-370
5. Kloos WE, Bannerman TL (1994) Update on clinical significance of coagulase-negative staphylococci. Clin Microbiol Rev 7:117-140
6. Richard P, Amador Del Valle G, Moreau P, Milpied N, Felice MP, Daeschler T, Harousseau JL, Richet H (1995) Viridans streptococcal bacteraemia in patients with neutropenia. Lancet 345:1607-1609
7. Shahdad SA, Taylor C, Barclay SC, Steen IN, Preshaw PM (2005) A double-blind, crossover study of Biotene Oralbalance and BioXtra systems as salivary substitutes in patients with post-radiotherapy xerostomia. Eur J Cancer Care (Engl) 14:319-326
8. Tenovuo J (1998) Antimicrobial function of human saliva-how important is it for oral health. Acta Odontol Scand 56:250-256
9. Warde P, Kroll B, O'Sullivan B, Aslanidis J, Tew-George E, Waldron J, Maxymiw W, Liu FF, Payne D, Cummings B (2000) A phase II study of Biotene in the treatment of postradiation xerostomia in patients with head and neck cancer. Support Care Cancer 8:203-208