Isolation of liver aldehyde oxidase containing fractions from different animals and determination of kinetic parameters for benzaldehyde

Indian Journal of Pharmaceutical Sciences

Volumn 70, Issue 1, 2008, Pages 85-88

  Kadam, R ^a   Iyer, K ^a  

^a BOMBAY COLLEGE OF PHARMACY   (India)

Author keywords

Benzaldehyde; Guinea pig; Hepatic; Liver aldehyde oxidase; Rabbit

Indexed keywords

ALDEHYDE OXIDASE; AMMONIUM SULFATE; BENZALDEHYDE; BENZOIC ACID; LIVER ENZYME;

ARTICLE; CHEMICAL PARAMETERS; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME ISOLATION; ENZYME KINETICS; GUINEA PIG; HEAT TREATMENT; MOUSE; NONHUMAN; PRECIPITATION; RABBIT; RAT; SPECTROPHOTOMETRY;

EID: 43449103093     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.40337     Document Type: Article

References (14)

1. Kurosaki M, Demontis S, Barzago MM, Garattini E, Terao M. Molecular cloning of the cDNA coding for mouse liver aldehyde oxidase-Tissue distribution and regulation in vivo by testosterone. Biochem J 1999;34:71-80.
2. Rettie AE, Fisher MB. Transformation enzymes: Oxidative; Non-P450. In: Woolf TF, editor. Handbook of drug metabolism. New York: Marcel Dekker Inc; 1999. p. 131-51.
3. Garattini E, Mendel R, Romao MJ, Wright R, Terao M. Mammalian molybdo-flavoenzymes, an expanding family of proteins; structure, genetics, regulation, function and pathophysiology. Biochem J 2003;372:15-32.
4. Calzi ML, Raviolo C, Ghibaudi E, Giola LD, Salmona M, Cazzaniga G, Kurosaki M, Terao M, Garattini E. Purification, cDNA cloning and tissue distribution of bovine liver aldehyde oxidase. Biochem Mol Biol 1995;270:31037-45.
5. Rajagopalan K, Handler P. Aldehyde oxidase. Methods Enzymol 1973;9:364-7.
6. Maia L, Mira L. Xanthine oxidase and aldehyde oxidase: A simple method for the simultaneous purification. Arch Biochem Biophys 2002;400:48-53.
7. Krenitsky TA, Neil SM, Elion GB, Hitchings GH. Comparison of the specificities of xanthine oxidase and aldehyde oxidase. Arch Biochem Biophys 1972;150:585-99.
8. Rashidi MR, Smith JA, Clarke SE, Beedham C. In vitro oxidation of famcylclovir and 6-deoxyfamcyclovir by aldehyde oxidase from human, guinea pig, rabbit and rat liver. Drug Metab Dispos 1997;25:805-16.
9. 1-Methylnicotinamide oxidation in number of mammals. J Biol Chem 1967;242:1274-9.
10. Kitamura S, Nakatani K, Ohashi K, Sugihara K, Hosokawa R, Akagawa Y, Ohta S. Extremely high drug-reductase activity based on aldehyde oxidase in monkey liver. Biol Pharm Bull 2001;24:856-9.
11. Houston JB, Kenworthy KE, Galetin A. Typical and atypical enzyme kinetics. In: Lee JS, Obach RS, Fisher MB, editors. Drug metabolizing enzymes-Cytochrome P450 and other enzymes in drug discovery and development, Netherlands and New York: FontisMedia S.A. and Marcel Dekker Inc; 2003. p. 211-54.
12. Dixon M, Webb EC, editors. Enzymes. 3rd ed. New York: Academic Press Inc; 1979.
13. Sugiharo K, Katsuma Y, Tanaka C, Kitamura S. Purification and some properties of hamster liver aldehyde oxidase. Biol Pharm Bull 1999;22:1246-8.
14. Panoutsopoulos GJ, Beedham C. Kinetics and specificity of guinea pig liver aldehyde oxidase and bovine milk xanthine oxidase towards substituted aldehydes. Acta Biochim Pol 2004;51:649-63.