Characterization of the murine CTP:phosphocholine cytidylyltransferase beta gene promoter

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1781, Issue 5, 2008, Pages 254-262

  Marcucci, Hebe ^a   Elena, Claudia ^a   Gilardoni, Paola ^a   Banchio, Claudia ^a  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

Author keywords

Brain; Cytidylyltransferase; Pcyt1b gene promoter; Phosphatidylcholine; Testis

Indexed keywords

CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE BETA2; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE BETA3; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; BIOINFORMATICS; CONTROLLED STUDY; GENE; GENE SEQUENCE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PCYT1B GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION;

ANIMALS; BASE SEQUENCE; BRAIN; CELL LINE; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; COMPUTATIONAL BIOLOGY; GENE DELETION; ISOENZYMES; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS);

MAMMALIA; MURINAE;

EID: 43449098542     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbalip.2008.03.006     Document Type: Article

References (35)

1. Jackowski S., Wang J., and Baburina I. Activity of the phosphatidylcholine biosynthetic pathway modulates the distribution of fatty acids into glycerolipids in proliferating cells. Biochim. Biophys. Acta 1483 (2000) 301-315
2. Vance J.E., and Vance D.E. Phospholipid biosynthesis in mammalian cells. Biochem. Cell. Biol. 82 (2004) 113-128
3. Karim M., Jackson P., and Jackowski S. Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform. Biochim. Biophys. Acta 1633 (2003) 1-12
4. Lykidis A., Murti K.G., and Jackowski S. Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase. J. Biol. Chem. 273 (1998) 14022-14029
5. Lykidis A., Baburina I., and Jackowski S. Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant. J. Biol. Chem. 274 (1999) 26992-27001
6. Tang W., Keesler G.A., and Tabas I. The structure of the gene for murine CTP:phosphocholine cytidylyltransferase, Ctpct. Relationship of exon structure to functional domains and identification of transcriptional start sites and potential upstream regulatory elements. J. Biol. Chem. 272 (1997) 13146-13151
7. Kalmar G.B., Kay R.J., Lachance A., Aebersold R., and Cornell R.B. Cloning and expression of rat liver CTP: phosphocholine cytidylyltransferase: an amphipathic protein that controls phosphatidylcholine synthesis. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 6029-6033
8. Feldman D.A., and Weinhold P.A. CTP:phosphorylcholine cytidylyltransferase from rat liver. Isolation and characterization of the catalytic subunit. J. Biol. Chem. 262 (1987) 9075-9081
9. Wang Y., and Kent C. Identification of an inhibitory domain of CTP:phosphocholine cytidylyltransferase. J. Biol. Chem. 270 (1995) 18948-18952
10. Carter J.M., Waite K.A., Campenot R.B., Vance J.E., and Vance D.E. Enhanced expression and activation of CTP:phosphocholine cytidylyltransferase beta2 during neurite outgrowth. J. Biol. Chem. 278 (2003) 44988-44994
11. Carter J.M., Demizieux L., Campenot R.B., Vance D.E., and Vance J.E. Phosphatidylcholine biosynthesis via CTP: Phosphocholine cytidylyltransferase beta 2 facilitates neurite outgrowth and branching. J. Biol. Chem. 283 (2007) 202-212
12. Jackowski S., Rehg J.E., Zhang Y.M., Wang J., Miller K., Jackson P., and Karim M.A. Disruption of CCTbeta2 expression leads to gonadal dysfunction. Mol. Cell. Biol. 24 (2004) 4720-4733
13. Safinya C.R. Structures of lipid-DNA complexes: supramolecular assembly and gene delivery. Curr. Opin. Struct. Biol. 11 (2001) 440-448
14. Andrews N.C., and Faller D.V. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19 (1991) 2499
15. Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., Hsieh F., Diatchenko L., Marusina K., Farmer A.A., Rubin G.M., Hong L., Stapleton M., Soares M.B., Bonaldo M.F., Casavant T.L., Scheetz T.E., Brownstein M.J., Usdin T.B., Toshiyuki S., Carninci P., Prange C., Raha S.S., Loquellano N.A., Peters G.J., Abramson R.D., Mullahy S.J., Bosak S.A., McEwan P.J., McKernan K.J., Malek J.A., Gunaratne P.H., Richards S., Worley K.C., Hale S., Garcia A.M., Gay L.J., Hulyk S.W., Villalon D.K., Muzny D.M., Sodergren E.J., Lu X., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Young A.C., Shevchenko Y., Bouffard G.G., Blakesley R.W., Touchman J.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Krzywinski M.I., Skalska U., Smailus D.E., Schnerch A., Schein J.E., Jones S.J., and Marra M.A. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 16899-16903
16. Banchio C., Schang L.M., and Vance D.E. Activation of CTP:phosphocholine cytidylyltransferase alpha expression during the S phase of the cell cycle is mediated by the transcription factor Sp1. J. Biol. Chem. 278 (2003) 32457-32464
17. Wisdom R. AP-1: one switch for many signals. Exp. Cell Res. 253 (1999) 180-185
18. Herdegen T., and Waetzig V. AP-1 proteins in the adult brain: facts and fiction about effectors of neuroprotection and neurodegeneration. Oncogene 20 (2001) 2424-2437
19. Hoffman G.E., Smith M.S., and Verbalis J.G. c-Fos and related immediate early gene products as markers of activity in neuroendocrine systems. Front. Neuroendocrinol. 14 (1993) 173-213
20. Voelker D.R., and Kennedy E.P. Cellular and enzymic synthesis of sphingomyelin. Biochemistry 21 (1982) 2753-2759
21. Hogan M., Kuliszewski M., Lee W., and Post M. Regulation of phosphatidylcholine synthesis in maturing type II cells: increased mRNA stability of CTP:phosphocholine cytidylyltransferase. Biochem. J. 314 Pt 3 (1996) 799-803
22. McCoy D.M., Fisher K., Robichaud J., Ryan A.J., and Mallampalli R.K. Transcriptional regulation of lung cytidylyltransferase in developing transgenic mice. Am. J. Respir. Cell Mol. Biol. 35 (2006) 394-402
23. Rye K.A., and Duong M.N. Influence of phospholipid depletion on the size, structure, and remodeling of reconstituted high density lipoproteins. J. Lipid Res. 41 (2000) 1640-1650
24. Hevonoja T., Pentikainen M.O., Hyvonen M.T., Kovanen P.T., and Ala-Korpela M. Structure of low density lipoprotein (LDL) particles: basis for understanding molecular changes in modified LDL. Biochim. Biophys. Acta 1488 (2000) 189-210
25. Clement J.M., and Kent C. CTP:phosphocholine cytidylyltransferase: insights into regulatory mechanisms and novel functions. Biochem. Biophys. Res. Commun. 257 (1999) 643-650
26. Cornell R.B. How cytidylyltransferase uses an amphipathic helix to sense membrane phospholipid composition. Biochem. Soc. Trans. 26 (1998) 539-544
27. Dunne S.J., Cornell R.B., Johnson J.E., Glover N.R., and Tracey A.S. Structure of the membrane binding domain of CTP:phosphocholine cytidylyltransferase. Biochemistry 35 (1996) 11975-11984
28. Bakovic M., Waite K., Tang W., Tabas I., and Vance D.E. Transcriptional activation of the murine CTP:phosphocholine cytidylyltransferase gene (Ctpct): combined action of upstream stimulatory and inhibitory cis-acting elements. Biochim. Biophys. Acta 1438 (1999) 147-165
29. Bakovic M., Waite K.A., and Vance D.E. Functional significance of Sp1, Sp2, and Sp3 transcription factors in regulation of the murine CTP:phosphocholine cytidylyltransferase alpha promoter. J. Lipid Res. 41 (2000) 583-594
30. Bakovic M., Waite K., and Vance D.E. Oncogenic Ha-Ras transformation modulates the transcription of the CTP:phosphocholine cytidylyltransferase alpha gene via p42/44MAPK and transcription factor Sp3. J. Biol. Chem. 278 (2003) 14753-14761
31. Ayoubi T.A., and Van De Ven W.J. Regulation of gene expression by alternative promoters. FASEB J. 10 (1996) 453-460
32. Ito E., Toki T., Ishihara H., Ohtani H., Gu L., Yokoyama M., Engel J.D., and Yamamoto M. Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis. Nature 362 (1993) 466-468
33. Yomogida K., Ohtani H., Harigae H., Ito E., Nishimune Y., Engel J.D., and Yamamoto M. Developmental stage- and spermatogenic cycle-specific expression of transcription factor GATA-1 in mouse Sertoli cells. Development 120 (1994) 1759-1766
34. Park S., Kim D., Kaneko S., Szewczyk K.M., Nicosia S.V., Yu H., Jove R., and Cheng J.Q. Molecular cloning and characterization of the human AKT1 promoter uncovers its up-regulation by the Src/Stat3 pathway. J. Biol. Chem. 280 (2005) 38932-38941
35. Banchio C., Lingrell S., and Vance D.E. Sp-1 binds promoter elements that are regulated by retinoblastoma and regulate CTP:phosphocholine cytidylyltransferase-alpha transcription. J. Biol. Chem. 282 (2007) 14827-14835