Inducible nitric oxide synthase appears and is co-expressed with the neuronal isoform in interneurons of the rat hippocampus after transient ischemia induced by middle cerebral artery occlusion

Experimental Neurology

Volumn 211, Issue 2, 2008, Pages 433-440

  Corsani, Letizia ^a   Bizzoco, Elisa ^a   Pedata, Felicita ^a   Gianfriddo, Marco ^a   Faussone Pellegrini, Maria Simonetta ^a   Vannucchi, Maria Giuliana ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Cornu hammonis (CA); Dentate gyrus (DG); Focal transient ischemia; Hippocampus; Inducible nitric oxide synthase (iNOS); Interneurons; Neurogenesis; Neuronal nitric oxide synthase (nNOS)

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL RENEWAL; CONTROLLED STUDY; DENTATE GYRUS; ENZYME INDUCTION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INTERNEURON; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; INTERNEURONS; ISCHEMIC ATTACK, TRANSIENT; MALE; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, WISTAR;

EID: 43449092856     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2008.02.008     Document Type: Article

References (28)

1. Butler L., Kassed C.A., Sanberg P.R., Willing A.E., and Pennypacker K.R. Neurodegeneration in the rat hippocampus and striatum after middle cerebral artery occlusion. Brain Res. 929 (2002) 252-260
2. Dalkara T., and Moskowitz M.A. The complex role of nitric oxide in the pathophysiology of focal cerebral ischaemia. Brain Pathol. 4 (1994) 49-57
3. Dun N.J., Dun S.L., Wong R.K.S., and Forstermann U. Colocalization of nitric oxide synthase and somatostatin immunoreactivity in the rat dentate hilar neurons. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 2955-2959
4. Eriksson P.S., Perfilieva E., Bjork-Eriksson T., Alborn A.M., Nordborg C., Peterson D.A., and Gage F.H. Neurogenesis in the adult human hippocampus. Nat. Med. 4 (1998) 1313-1317
5. Garthwaite J. Glutamate, nitric oxide and cell-cell signalling in the nervous system. Trends Neurosci. 14 (1991) 60-67
6. Holtz M.L., Craddock S.D., and Creed Pettigrew L. Rapid expression of neuronal and inducible nitric oxide synthases during post-ischemic reperfusion in rat brain. Brain Res. 898 (2001) 49-60
7. Kaplan M.S., and Hinds J.W. Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs. Science 197 (1977) 1092-1094
8. Keynes R.G., and Garthwaite J. Nitric oxide and its role in ischemic brain injury. Curr. Mol. Med. 4 (2004) 179-191
9. Kirino T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 239 (1982) 57-69
10. Kornack D.R., and Rakic P. Continuation of neurogenesis in the hippocampus of the adult macaque monkey. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 5768-5773
11. Jin K., Minami M., Lan J.Q., Mao X.O., Batteur S., Simon R.P., and Greenberg D.A. Neurogenesis in the dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 4710-4715
12. Jin K., Sun Y., Xie L., Peel A., Mao X.O., Batteur S., and Greenberg D.A. Directed migration of neuronal precursors into the ischemic cerebral cortex and striatum. Mol. Cell. Neurosci. 24 (2003) 171-189
13. Melani A., Pantoni L., Corsi C., Bianchi L., Monopoli A., Bertorelli R., Pepeu G., and Pedata F. Striatal outflow of adenosine, excitatory amino acids, gamma-aminobutyric acid, and taurine in awake freely moving rats after middle cerebral artery occlusion: correlations with neurological deficit and histopathological damage. Stroke 30 (1999) 2448-2454
14. Nogawa S., Forster C., Zhang F., Nagayama M., Ross M.E., and Iadecola C. Interaction between inducible nitric oxide synthase and cyclooxigenase-2 after cerebral ischemia. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 10966-10971
15. Packer M.A., Stasiv Y., Benraiss A., Chmielnicki E., Grinberg A., Westphal H., Goldman S.A., and Enikolopov G. Nitric oxide negatively regulates mammalian adult neurogenesis. Proc. Natl. Acad. Sci. U S. A. 100 (2003) 9566-9571
16. Parent J.M., Vexler Z.S., Gong C., Derugin N., and Ferriero D.M. Rat forebrain neurogenesis and striatal neuron replacement after focal stroke. Ann. Neurol. 52 (2002) 802-813
17. Rietze R., Poulin P., and Weiss S. Mitotically active cells that generate neurons and astrocytes are present in multiple regions of the adult mouse hippocampus. J. Comp. Neurol. 424 (2000) 397-408
18. Sasaki T., Hamada J., Shibata M., Araki N., and Fukuuchi Y. Inhibition of nitric oxide production during global ischemia ameliorates ischemic damage of pyramidal neurons in the hippocampus. Keio J. Med. 50 (2001) 182-187
19. Schmidt-Kastner R., and Freund T.F. Selective vulnerability of the hippocampus in brain ischemia. Neuroscience 40 (1991) 599-636
20. Squire L.R. Memory and the hippocampus: a synthesis of findings from rats, monkeys and humans. Psychol. Rev. 99 (1992) 195-231
21. Sun Y., Kunlin J., Childs J.T., Xie L., Mao X.O., and Greenberg D.A. Neuronal nitric oxide synthase and ischemia-induced neurogenesis. J. Cerebr. Blood Flow Metab. 25 (2005) 485-492
22. Valtschanoff J.G., Weimberg R.J., Kharazia V.N., Nakane M., and Schmidt H.H.H.W. Neurons in rat hippocampus that synthesize nitric oxide. J. Comp. Neurol. 331 (1993) 111-121
23. Vannucchi M.G., Corsani L., Gianfriddo M., Pedata F., and Faussone-Pellegrini M.S. Expression of neuronal and inducible nitric oxide synthase in neuronal and glial cells after transient occlusion of the middle cerebral artery. Neuroscience 136 (2005) 1015-1026
24. Vannucchi M.G., Bizzoco E., Corsani L., Gianfriddo M., Pedata F., and Faussone-Pellegrini M.S. Relationships between neurons expressing neuronal nitric oxide synthase, degree of microglia activation and animal survival. A study in the rat cortex after transient ischemia. Brain Res. 1132 (2007) 218-227
25. Wendland B., Schweizer F.E., Ryan T.A., Nakane M., Murad F., Scheller R.H., and Tsien R.W. Existence of nitric oxide synthase in rat hippocampal pyramidal cells. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 2151-2155
26. Zea Longa E., Weinstein P.R., Carison S., and Cummins R. Reversible middle cerebral artery occlusion without craniotomy in rats. Stroke 20 (1989) 84-91
27. Zhu D.Y., Liu S.H., Sun H.S., and Lu Y.M. Expression of inducible nitric oxide synthase after focal cerebral ischemia stimulates neurogenesis in the adult rodent dentate gyrus. J. Neurosci. 23 (2003) 223-229
28. Zhu X.J., Hua Y., Jiang J., Zhou Q.G., Luo C.X., Han X., Lu Y.M., and Zhu D.Y. Neuronal nitric oxide synthase-derived nitric oxide inhibits neurogenesis in the adult dentate gyrus by down-regulating cyclic AMP response element binding protein phosphorylation. Neuroscience 141 (2006) 827-836