Ouabain at nanomolar concentration promotes synthesis and release of angiotensin II from the endothelium of the tail vascular bed of spontaneously hypertensive rats

Journal of Cardiovascular Pharmacology

Volumn 44, Issue 3, 2004, Pages 372-380

  Padilha, Alessandra Simão ^a   Rossoni, Luciana Venturini ^b   Xavier, Fabiano Elias ^a   Vassallo, Dalton Valentin ^a,c  

^a FEDERAL UNIVERSITY OF ESPÍRITO SANTO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c Sch Med S Casa Misericordia V   (Brazil)

Author keywords

ACE; Angiotensin II; Endothelium; K + ATPase; Na +; Ouabain; SHR

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANGIOTENSIN; DIPEPTIDYL CARBOXYPEPTIDASE; ENALAPRILAT; LOSARTAN; OUABAIN; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD VESSEL REACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG SENSITIVITY; ENDOTHELIUM LESION; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; TAIL; VASCULAR ENDOTHELIUM;

ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; ENALAPRILAT; ENDOTHELIUM, VASCULAR; GLUCOSE; HEXAMETHONIUM; INJECTIONS, INTRAVENOUS; LOSARTAN; MALE; MUSCLE, SMOOTH, VASCULAR; NA(+)-K(+)-EXCHANGING ATPASE; OUABAIN; PERFUSION; PHENYLEPHRINE; POTASSIUM CHLORIDE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; TAIL; TIME FACTORS; TROMETHAMINE; VASODILATION;

EID: 4344703079     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fjc.0000138165.96364.51     Document Type: Article

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