메뉴 건너뛰기




Volumn 41, Issue 1, 2003, Pages 105-116

Ouabain changes arterial blood pressure and vascular reactivity to phenylephrine in L-NAME-induced hypertension

Author keywords

EDHF; Endothelium; L NAME; Nitric oxide; Ouabain; Phenylephrine; Vascular smooth muscle

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); HEXAMETHONIUM; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; OUABAIN; PHENYLEPHRINE; POTASSIUM CHANNEL STIMULATING AGENT; SODIUM; TETRYLAMMONIUM;

EID: 0037215391     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200301000-00014     Document Type: Article
Times cited : (23)

References (50)
  • 1
    • 0025990187 scopus 로고
    • The pathogenesis of essential hypertension: A link between dietary salt and high blood pressure
    • Blaustein MP, Hamlyn JM. The pathogenesis of essential hypertension: A link between dietary salt and high blood pressure. Hypertension 1991;18(suppl III):III184-95.
    • (1991) Hypertension , vol.18 , Issue.SUPPL. III
    • Blaustein, M.P.1    Hamlyn, J.M.2
  • 2
    • 0024439567 scopus 로고
    • Endotheliumderived vasoactive substances: Potential role in hypertension, atherosclerosis, and vascular occlusion
    • Lüscher TF, Yang Z, Diederich D, et al. Endotheliumderived vasoactive substances: Potential role in hypertension, atherosclerosis, and vascular occlusion. J Cardiovasc Pharmacol 1989;14(suppl 6):S63-9.
    • (1989) J Cardiovasc Pharmacol , vol.14 , Issue.SUPPL. 6
    • Lüscher, T.F.1    Yang, Z.2    Diederich, D.3
  • 3
    • 0024360030 scopus 로고
    • Endothelium and control of vascular function: State of the art lecture
    • Vanhoutte PM. Endothelium and control of vascular function: State of the art lecture. Hypertension 1989;13(3 pt 2): 658-67.
    • (1989) Hypertension , vol.13 , Issue.3 PART 2 , pp. 658-667
    • Vanhoutte, P.M.1
  • 4
    • 78651143323 scopus 로고
    • Neurogenic hypertension in the rat
    • Krieger EM. Neurogenic hypertension in the rat. Circ Res 1964;15:511-21.
    • (1964) Circ Res , vol.15 , pp. 511-521
    • Krieger, E.M.1
  • 5
    • 0019963499 scopus 로고
    • The sympathetic system in hypertension: State of the art review
    • Abboud FM. The sympathetic system in hypertension: State of the art review. Hypertension 1982;4(3 pt 2):208-25.
    • (1982) Hypertension , vol.4 , Issue.3 PART 2 , pp. 208-225
    • Abboud, F.M.1
  • 6
    • 0026576613 scopus 로고
    • Rat adrenal cortex is a source of a circulating ouabain-like compound
    • Ludens JH, Clark MA, Robinson FG, et al. Rat adrenal cortex is a source of a circulating ouabain-like compound. Hypertension 1992;19:721-4.
    • (1992) Hypertension , vol.19 , pp. 721-724
    • Ludens, J.H.1    Clark, M.A.2    Robinson, F.G.3
  • 7
    • 0025821399 scopus 로고
    • Identification and characterization of an ouabain-like compound from human plasma
    • Hamlyn JM, Blaustein MP, Bova S, et al. Identification and characterization of an ouabain-like compound from human plasma. Proc Natl Acad Sci U S A 1991;88:6259-63.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 6259-6263
    • Hamlyn, J.M.1    Blaustein, M.P.2    Bova, S.3
  • 8
  • 9
    • 0027312742 scopus 로고
    • Long-term ouabain administration produces hypertension in rats
    • Yuan CM, Manunta P, Hamlyn JM, et al. Long-term ouabain administration produces hypertension in rats. Hypertension 1993;22:178-87.
    • (1993) Hypertension , vol.22 , pp. 178-187
    • Yuan, C.M.1    Manunta, P.2    Hamlyn, J.M.3
  • 10
    • 0028271160 scopus 로고
    • Ouabaininduced hypertension in the rat: Relationships among circulating and tissue ouabain and blood pressure
    • Manunta P, Rogowski AC, Hamilton BP, et al. Ouabaininduced hypertension in the rat: Relationships among circulating and tissue ouabain and blood pressure. J Hypertens 1994;12:549-60.
    • (1994) J Hypertens , vol.12 , pp. 549-560
    • Manunta, P.1    Rogowski, A.C.2    Hamilton, B.P.3
  • 11
    • 0036838643 scopus 로고    scopus 로고
    • Ouabain-induced hypertension is accompanied by increases in endothelial vasodilator factors
    • Rossoni LV, Salaices M, Miguel M, et al. Ouabain-induced hypertension is accompanied by increases in endothelial vasodilator factors. Am J Physiol Heart Circ Physiol 2002;283:H2110-8.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Rossoni, L.V.1    Salaices, M.2    Miguel, M.3
  • 12
    • 0026641313 scopus 로고
    • Physiology and pharmacology of endogenous digitalis-like factors
    • Goto A, Yamada K, Yagi N, et al. Physiology and pharmacology of endogenous digitalis-like factors. Pharmacol Rev 1992;44:377-99.
    • (1992) Pharmacol Rev , vol.44 , pp. 377-399
    • Goto, A.1    Yamada, K.2    Yagi, N.3
  • 13
    • 0027174426 scopus 로고
    • 2+ stores and cell responsiveness
    • 2+ stores and cell responsiveness. Am J Physiol 1993;264:C1367-87.
    • (1993) Am J Physiol , vol.264
    • Blaustein, M.P.1
  • 14
    • 0031852360 scopus 로고    scopus 로고
    • The cellular mechanism of action of cardiotonic steroids: A new hypothesis
    • Blaustein MP, Juhaszova M, Golovina VA. The cellular mechanism of action of cardiotonic steroids: A new hypothesis. Clin Exper Hypertens 1998;20:691-703.
    • (1998) Clin Exper Hypertens , vol.20 , pp. 691-703
    • Blaustein, M.P.1    Juhaszova, M.2    Golovina, V.A.3
  • 16
    • 0029548989 scopus 로고
    • Ouabain amplifies contractile responses to phenylephrine in rat tail arteries in hypertension
    • Songu-Mize E, Vassallo DV, Rashed SM, et al. Ouabain amplifies contractile responses to phenylephrine in rat tail arteries in hypertension. J Basic Clin Physiol Pharmacol 1995;6:309-19.
    • (1995) J Basic Clin Physiol Pharmacol , vol.6 , pp. 309-319
    • Songu-Mize, E.1    Vassallo, D.V.2    Rashed, S.M.3
  • 17
    • 0030053793 scopus 로고    scopus 로고
    • Low concentrations of ouabain increase cytosolic free calcium concentration in rat vascular smooth muscle cells
    • Zhu Z, Tepel M, Neusser M, et al. Low concentrations of ouabain increase cytosolic free calcium concentration in rat vascular smooth muscle cells. Clin Sci 1996;90:9-12.
    • (1996) Clin Sci , vol.90 , pp. 9-12
    • Zhu, Z.1    Tepel, M.2    Neusser, M.3
  • 18
    • 0032757339 scopus 로고    scopus 로고
    • The influence of nanomolar ouabain on vascular pressor responses is modulated by the endothelium
    • Rossoni LV, Cunha V, França A, et al. The influence of nanomolar ouabain on vascular pressor responses is modulated by the endothelium. J Cardivasc Pharmacol 1999;34: 887-982.
    • (1999) J Cardivasc Pharmacol , vol.34 , pp. 887-982
    • Rossoni, L.V.1    Cunha, V.2    França, A.3
  • 19
    • 0029914259 scopus 로고    scopus 로고
    • Endothelial modulation of ouabain-induced contraction and sodium pump activity in aortas of normotensive Wistar-Kyoto and spontaneously hypertensive rats
    • Ponte A, Marín J, Arribas S, et al. Endothelial modulation of ouabain-induced contraction and sodium pump activity in aortas of normotensive Wistar-Kyoto and spontaneously hypertensive rats. J Vasc Res 1996;33:164-74.
    • (1996) J Vasc Res , vol.33 , pp. 164-174
    • Ponte, A.1    Marín, J.2    Arribas, S.3
  • 20
    • 0026793255 scopus 로고
    • Endothelial modulation of the ouabain-induced contraction in human placental vessels
    • Sánchez-Ferrer CF, Fernández-Alfonso MS, Ponte A, et al. Endothelial modulation of the ouabain-induced contraction in human placental vessels. Circ Res 1992;71:943-50.
    • (1992) Circ Res , vol.71 , pp. 943-950
    • Sánchez-Ferrer, C.F.1    Fernández-Alfonso, M.S.2    Ponte, A.3
  • 21
    • 0027405558 scopus 로고
    • Ouabain enhances basal release of nitric oxide from carotid artery
    • Xie J, Wang Y, Summer WR, et al. Ouabain enhances basal release of nitric oxide from carotid artery. Am J Med Sci 1993;305:157-63.
    • (1993) Am J Med Sci , vol.305 , pp. 157-163
    • Xie, J.1    Wang, Y.2    Summer, W.R.3
  • 22
    • 0033911859 scopus 로고    scopus 로고
    • Nitric oxide synthase induction by ouabain in vascular smooth muscle cells from normotensive and hypertensive rats
    • Pacheco ME, Marfn J, Manso AM, et al. Nitric oxide synthase induction by ouabain in vascular smooth muscle cells from normotensive and hypertensive rats. J Hypertens 2000;18:877-84.
    • (2000) J Hypertens , vol.18 , pp. 877-884
    • Pacheco, M.E.1    Marfn, J.2    Manso, A.M.3
  • 23
    • 0026782496 scopus 로고
    • Chronic inhibition of nitric oxide synthesis: A new model of arterial hypertension
    • Ribeiro MO, Antunes E, de Nucci G, et al. Chronic inhibition of nitric oxide synthesis: A new model of arterial hypertension. Hypertension 1992;20:298-303.
    • (1992) Hypertension , vol.20 , pp. 298-303
    • Ribeiro, M.O.1    Antunes, E.2    De Nucci, G.3
  • 24
    • 0027433665 scopus 로고
    • Evidence that the autonomic nervous system plays a major role in the L-NAME-induced hypertension in conscious rats
    • Cunha RS, Cabral AM, Vasquez EC. Evidence that the autonomic nervous system plays a major role in the L-NAME-induced hypertension in conscious rats. Am J Hypertens 1993;6:806-9.
    • (1993) Am J Hypertens , vol.6 , pp. 806-809
    • Cunha, R.S.1    Cabral, A.M.2    Vasquez, E.C.3
  • 25
    • 0033006108 scopus 로고    scopus 로고
    • Effects of antihypertensive therapy on factors mediating endothelium-dependent relaxation in rats treated chronically with L-NAME
    • Maeso R, Navarro-Cid J, Rodrigo E, et al. Effects of antihypertensive therapy on factors mediating endothelium-dependent relaxation in rats treated chronically with L-NAME. J Hypertens 1999;17:221-7.
    • (1999) J Hypertens , vol.17 , pp. 221-227
    • Maeso, R.1    Navarro-Cid, J.2    Rodrigo, E.3
  • 26
    • 0034055878 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitor reduces blood pressure elevation and vascular reactivity dysfunction caused by inhibition of nitric oxide synthase in rat
    • da Cunha V, Rossoni LV, Oliveira PA, et al. Cyclooxygenase inhibitor reduces blood pressure elevation and vascular reactivity dysfunction caused by inhibition of nitric oxide synthase in rat. Clin Exp Hypertens 2000;22:203-15.
    • (2000) Clin Exp Hypertens , vol.22 , pp. 203-215
    • Da Cunha, V.1    Rossoni, L.V.2    Oliveira, P.A.3
  • 27
    • 0035793321 scopus 로고    scopus 로고
    • Mechanisms of the increased pressor response to vasopressors in the mesenteric bed of nitric oxide-deficient hypertensive rats
    • Ruiz-Marcos FM, Ortíz MC, Fortepiani LA, et al. Mechanisms of the increased pressor response to vasopressors in the mesenteric bed of nitric oxide-deficient hypertensive rats. Eur J Pharmacol 2001;412:273-9.
    • (2001) Eur J Pharmacol , vol.412 , pp. 273-279
    • Ruiz-Marcos, F.M.1    Ortíz, M.C.2    Fortepiani, L.A.3
  • 28
    • 0034857209 scopus 로고    scopus 로고
    • Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats
    • Rossoni LV, Pinto VD, Vassallo DV. Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats. Braz J Med Biol Res 2001;34:1065-77.
    • (2001) Braz J Med Biol Res , vol.34 , pp. 1065-1077
    • Rossoni, L.V.1    Pinto, V.D.2    Vassallo, D.V.3
  • 29
  • 30
    • 0018183713 scopus 로고
    • + ATPase activity in the vascular smooth muscle
    • + ATPase activity in the vascular smooth muscle. Blood Vessels 1978;15:198-207.
    • (1978) Blood Vessels , vol.15 , pp. 198-207
    • Webb, R.C.1    Bohr, D.F.2
  • 31
    • 0032585865 scopus 로고    scopus 로고
    • Vascular sodium pump: Endothelial modulation and alterations in some pathologic processes and aging
    • Marín J, Redondo J. Vascular sodium pump: Endothelial modulation and alterations in some pathologic processes and aging. Pharmacol Ther 1999;84:249-71.
    • (1999) Pharmacol Ther , vol.84 , pp. 249-271
    • Marín, J.1    Redondo, J.2
  • 32
    • 0021188040 scopus 로고
    • Phasic vascular sodium pump changes in deoxycorticosterone-hypertensive rats
    • Songu-Mize E, Bealer SL, Calwell RW. Phasic vascular sodium pump changes in deoxycorticosterone-hypertensive rats. Circ Res 1984;55:304-8.
    • (1984) Circ Res , vol.55 , pp. 304-308
    • Songu-Mize, E.1    Bealer, S.L.2    Calwell, R.W.3
  • 33
    • 0023597881 scopus 로고
    • +-TPase inhibitor in the plasma of normotensive and hypertensive humans and rats
    • +-TPase inhibitor in the plasma of normotensive and hypertensive humans and rats. Hypertension 1987;10 (suppl 1):152-6.
    • (1987) Hypertension , vol.10 , Issue.SUPPL. 1 , pp. 152-156
    • De Wardener, H.E.1    Millett, J.2    Holland, S.3
  • 34
    • 0021253637 scopus 로고
    • Circulating digitalis-like substance is increased in DOCA-salt hypertension
    • Kojina I. Circulating digitalis-like substance is increased in DOCA-salt hypertension. Biochem Biophys Res Com 1984;122:129-36.
    • (1984) Biochem Biophys Res Com , vol.122 , pp. 129-136
    • Kojina, I.1
  • 35
    • 0034693294 scopus 로고    scopus 로고
    • Effects of ouabain on the pressor response to phenylephrine and on the sodium pump activity in diabetic rats
    • Davel APC, Rossoni LV, Vassallo DV. Effects of ouabain on the pressor response to phenylephrine and on the sodium pump activity in diabetic rats. Eur J Pharmacol 2000;406:419-27.
    • (2000) Eur J Pharmacol , vol.406 , pp. 419-427
    • Davel, A.P.C.1    Rossoni, L.V.2    Vassallo, D.V.3
  • 36
    • 0021253503 scopus 로고
    • +-ATPase inhibitors and the adrenergic neuroeffector interaction in blood vessel wall
    • +-ATPase inhibitors and the adrenergic neuroeffector interaction in blood vessel wall. J Cardiovasc Pharmacol 1984;6(suppl 1):88-94.
    • (1984) J Cardiovasc Pharmacol , vol.6 , Issue.SUPPL. 1 , pp. 88-94
    • Vanhoutte, P.M.1    Lorenz, R.R.2
  • 37
    • 0023884885 scopus 로고
    • Effects of ouabain on isolated cerebral and femoral arteries of the cat: A functional and biochemical study
    • Marín J, Sánchez-Ferrer CF, Salaices M. Effects of ouabain on isolated cerebral and femoral arteries of the cat: A functional and biochemical study. Br J Pharmacol 1988; 93:43-52.
    • (1988) Br J Pharmacol , vol.93 , pp. 43-52
    • Marín, J.1    Sánchez-Ferrer, C.F.2    Salaices, M.3
  • 38
    • 0035127131 scopus 로고    scopus 로고
    • Acute pressor actions of ouabain do not enhance the actions of phenylephrine or norepinephrine in anesthetized rats
    • Barker LA, Rossoni LV, Vassallo DV. Acute pressor actions of ouabain do not enhance the actions of phenylephrine or norepinephrine in anesthetized rats. J Cardiovasc Pharmacol 2001;37:339-48.
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 339-348
    • Barker, L.A.1    Rossoni, L.V.2    Vassallo, D.V.3
  • 39
    • 0021369834 scopus 로고
    • Effects of digoxin on responsiveness to pressor actions of angiotensin and norepinephrine in man
    • Guthrie GP Jr. Effects of digoxin on responsiveness to pressor actions of angiotensin and norepinephrine in man. J Clin Endoc Metab 1984;58:76-80.
    • (1984) J Clin Endoc Metab , vol.58 , pp. 76-80
    • Guthrie G.P., Jr.1
  • 40
    • 0030667103 scopus 로고    scopus 로고
    • Increased contractile response induced with ouabain is abolished by thapsigargin in aorta of renal hypertensive rats
    • Ceron PIB, Bendhack LM. Increased contractile response induced with ouabain is abolished by thapsigargin in aorta of renal hypertensive rats. Gen Pharmacol 1997;29:707-12.
    • (1997) Gen Pharmacol , vol.29 , pp. 707-712
    • Ceron, P.I.B.1    Bendhack, L.M.2
  • 41
    • 0027143336 scopus 로고
    • Nanomolar ouabain augments caffeine-evoked contractions in rats arteries
    • Weiss DN, Podberesky DJ, Heidrich J, et al. Nanomolar ouabain augments caffeine-evoked contractions in rats arteries. Am J Physiol 1994;265:C1443-8.
    • (1994) Am J Physiol , vol.265
    • Weiss, D.N.1    Podberesky, D.J.2    Heidrich, J.3
  • 42
    • 12244305724 scopus 로고    scopus 로고
    • Role of endothelium in the ouabain-enhanced response to phenylephrine (Phe)
    • Spon: Varner KJ
    • França AS, Cunha V, Vassallo DV (Spon: Varner KJ). Role of endothelium in the ouabain-enhanced response to phenylephrine (Phe) (abstract). FASEB J 1997;11:A80.
    • (1997) FASEB J , vol.11
    • França, A.S.1    Cunha, V.2    Vassallo, D.V.3
  • 43
    • 0025905340 scopus 로고
    • Effect of Ouabain on endothelium-dependent relaxation of human resistance arteries
    • Woolfson RG, Poston L. Effect of Ouabain on endothelium-dependent relaxation of human resistance arteries. Hypertension 1991;17:619-25.
    • (1991) Hypertension , vol.17 , pp. 619-625
    • Woolfson, R.G.1    Poston, L.2
  • 44
    • 0023867044 scopus 로고
    • Endothelium-dependent hyperpolarization of canine coronary smooth muscle
    • Félétou M, Vanhoutte PM. Endothelium-dependent hyperpolarization of canine coronary smooth muscle. Br J Pharmacol 1988;93:515-24.
    • (1988) Br J Pharmacol , vol.93 , pp. 515-524
    • Félétou, M.1    Vanhoutte, P.M.2
  • 45
    • 0343339988 scopus 로고    scopus 로고
    • Changes of sodium and ATP affinities of the cardiac (Na, K)-ATPase during and after nitric oxide deficient hypertension
    • Vrbjar N, Bernátová I, Pechánová O. Changes of sodium and ATP affinities of the cardiac (Na, K)-ATPase during and after nitric oxide deficient hypertension. Mol Cell Biochem 1999;202:141-7.
    • (1999) Mol Cell Biochem , vol.202 , pp. 141-147
    • Vrbjar, N.1    Bernátová, I.2    Pechánová, O.3
  • 46
    • 0029979216 scopus 로고    scopus 로고
    • + pump activity by insulin and nitric oxide in rabbit aorta
    • + pump activity by insulin and nitric oxide in rabbit aorta. Am J Physiol 1996;270:H1287-93.
    • (1996) Am J Physiol , vol.270
    • Gupta, S.1    Phipps, K.2    Ruderman, N.B.3
  • 47
    • 0035090156 scopus 로고    scopus 로고
    • Structure-activity relationships for the hypertensinogenic activity of ouabain: Role of the sugar and lactone ring
    • Manunta P, Hamilton BP, Hamlyn, JM. Structure-activity relationships for the hypertensinogenic activity of ouabain: Role of the sugar and lactone ring. Hypertension 2001;37 (pt 2):472-7.
    • (2001) Hypertension , vol.37 , Issue.PART 2 , pp. 472-477
    • Manunta, P.1    Hamilton, B.P.2    Hamlyn, J.M.3
  • 48
    • 6844250964 scopus 로고    scopus 로고
    • Ouabain produces diverse excitatory effects on afferent baroreceptor nerve activity in SHR and WKY animals
    • Abreu G, Futuro Neto HA, Cabral AM, et al. Ouabain produces diverse excitatory effects on afferent baroreceptor nerve activity in SHR and WKY animals. Clin Exper Hypertens 1998;20:85-94.
    • (1998) Clin Exper Hypertens , vol.20 , pp. 85-94
    • Abreu, G.1    Futuro Neto, H.A.2    Cabral, A.M.3
  • 49
    • 0032711839 scopus 로고    scopus 로고
    • L-arginine restores the effect of ouabain on baroreceptor activity and prevents hypertension
    • Abreu G, Futuro Neto HA, Cabral AM, et al. L-arginine restores the effect of ouabain on baroreceptor activity and prevents hypertension. Hypertension 1999;34(pt 2):729-32.
    • (1999) Hypertension , vol.34 , Issue.PART 2 , pp. 729-732
    • Abreu, G.1    Futuro Neto, H.A.2    Cabral, A.M.3
  • 50
    • 0031016891 scopus 로고    scopus 로고
    • Brain "ouabain" in the median preoptic nucleus mediates sodium-sensitive hypertension in spontaneously hypertensive rats
    • Budzikowski AS, Leenen FHH. Brain "ouabain" in the median preoptic nucleus mediates sodium-sensitive hypertension in spontaneously hypertensive rats. Hypertension 1997;29:599-605.
    • (1997) Hypertension , vol.29 , pp. 599-605
    • Budzikowski, A.S.1    Leenen, F.H.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.