Effects of sumatriptan on rat medullary dorsal horn neurons

Pain

Volumn 111, Issue 1-2, 2004, Pages 30-37

  Jennings, E A ^a,b   Ryan, R M ^a   Christie, M J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Analgesia; Migraine; Patch clamp electrophysiology; Trigeminal spinal caudal subnucleus

Indexed keywords

3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; 3 [4 (3 CHLOROPHENYL) 1 PIPERAZINYL] 1,1 DIPHENYL 2 PROPANOL; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; ANTIMIGRAINE AGENT; BACLOFEN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GLUTAMIC ACID; KETANSERIN; MESSENGER RNA; METENKEPHALIN; RECEPTOR SUBTYPE; SEROTONIN 1B AGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D ANTAGONIST; SEROTONIN 1D RECEPTOR; SUMATRIPTAN;

AMPLITUDE MODULATION; ANIMAL TISSUE; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG SELECTIVITY; EVOKED SPINAL CORD RESPONSE; EXAMINATION; INCUBATION TIME; MEDULLA OBLONGATA; MEMBRANE CURRENT; MUSCLE SPINDLE AFFERENT NERVE; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; STIMULUS; SUBSTANTIA GELATINOSA; SYNAPTOSOME; TRIGEMINAL NUCLEUS; TRIGEMINUS GANGLION;

ANIMALS; EXCITATORY POSTSYNAPTIC POTENTIALS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTOR, SEROTONIN, 5-HT1D; RNA, MESSENGER; SEROTONIN AGONISTS; SUBSTANTIA GELATINOSA; SUMATRIPTAN; TRIGEMINAL CAUDAL NUCLEUS;

EID: 4344702115     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2004.05.018     Document Type: Article

References (33)

1. Borgland S.L., Connor M., Ryan R.M., Ball H.J., Christie M.J. Prostaglandin E(2) inhibits calcium current in two sub-populations of acutely isolated mouse trigeminal sensory neurons. J Physiol (Lond). 539:2002;433-444
2. Bouchelet I., Cohen Z., Case B., Seguela P., Hamel E. Differential expression of sumatriptan-sensitive 5-hydroxytryptamine receptors in human trigeminal ganglia and cerebral blood vessels. Mol Pharmacol. 50:1996;219-223
3. 1F receptors) in human brain - focus on brainstem and spinal cord. Neuropharmacology. 36:1997;535-542
4. Goadsby P.J. The pharmacology of headache. Prog Neurobiol. 62:2000;509-525
5. Goadsby P.J., Hoskin K.L. Serotonin inhibits trigeminal nucleus activity evoked by craniovascular stimulation through a 5HT1B/1D receptor: a central action in migraine? Ann Neurol. 43:1998;711-718
6. Goadsby P.J., Akerman S., Storer R.J. Evidence for postjunctional serotonin (5-HT1) receptors in the trigeminocervical complex. Ann Neurol. 50:2001;804-807
7. Goadsby P.J., Lipton R.B., Ferrari M.D. Migraine - current understanding and treatment. N Engl J Med. 346:2002;257-270
8. Goldstein D.J., Wang O., Saper J.R., Stoltz R., Silberstein S.D., Mathew N.T. Ineffectiveness of neurokinin-1 antagonist in acute migraine: a crossover study. Cephalalgia. 17:1997;785-790
9. Grudt T.J., Williams J.T. mu-Opioid agonists inhibit spinal trigeminal substantia gelatinosa neurons in guinea pig and rat. J Neurosci. 14:1994;1646-1654
10. Grudt T.J., Williams J.T., Travagli R.A. Inhibition by 5-hydroxytryptamine and noradrenaline in substantia gelatinosa of guinea-pig spinal trigeminal nucleus. J Physiol (Lond). 485:1995;113-120
11. Hanoun N., Saurini F., Lanfumey L., Hamon M., Bourgoin S. Dihydroergotamine and its metabolite, 8′-hydroxy-dihydroergotamine, as 5-HT1A receptor agonists in the rat brain. Br J Pharmacol. 139:2003;424-434
12. Hou M., Kanje M., Longmore J., Tajti J., Uddman R., Edvinsson L. 5-HT(1B) and 5-HT(1D) receptors in the human trigeminal ganglion: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase. Brain Res. 909:2001;112-120
13. Jennings E.A., Vaughan C.W., Christie M.J. Cannabinoid actions on rat superficial medullary dorsal horn neurons in vitro. J Physiol (Lond). 534:2001;805-812
14. Jennings E.A., Ryan R.M., Christie M.J. Effect of sumatriptan on rat medullary dorsal horn neurons. Dostrovsky J.O., Carr D.B., Koltzenburg M. Proceedings of the 10th World Congress on Pain. vol. 24:2003;481-487 IASP Press, Seattle, WA
15. Kaube H., Hoskin K.L., Goadsby P.J. Inhibition by sumatriptan of central trigeminal neurones only after blood-brain barrier disruption. Br J Pharmacol. 109:1993;788-792
16. Kaube H., Keay K.A., Hoskin K.L., Bandler R., Goadsby P.J. Expression of c-Fos-like immunoreactivity in the caudal medulla and upper cervical spinal cord following stimulation of the superior sagittal sinus in the cat. Brain Res. 629:1993;95-102
17. Light A.R., Shults R.C., Jones S.L. The initial processing of pain and its descending control: spinal and trigeminal systems. 1992;Karger, Basel. 306 p
18. Longmore J., Shaw D., Smith D., Hopkins R., McAlliste G., Pickard J., Sirinathsinghji D., Butler A., Hill R. Differential distribution of 5HT1D- and 5HT1B-immunoreactivity within the human trigemino-cerebrovascular system: implications for the discovery of new antimigraine drugs. Cephalalgia. 17:1997;833-842
19. Luscher C., Jan L.Y., Stoffel M., Malenka R.C., Nicoll R.A. G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron. 19:1997;687-695
20. Ma Q.-P., Hill R., Sirinathsinghji D. Colocalization of CGRP with 5-HT1B/1D receptors and substance P in trigeminal ganglion neurons in rats. Eur J Neurosci. 13:2001;2099-2104
21. Messlinger K., Ebersberger A., Schaible H.G. Release of immunoreactive substance P in the brain stem upon stimulation of the cranial dura mater with low pH - inhibition by the serotonin (5-HT1) receptor agonist CP 93,129. Br J Pharmacol. 125:1998;1726-1732
22. Nozaki K., Moskowitz M.A., Boccalini P. CP-93,129, sumatriptan, dihydroergotamine block c-fos expression within rat trigeminal nucleus caudalis caused by chemical stimulation of the meninges. Br J Pharmacol. 106:1992;409-415
23. Peroutka S.J. Pharmacological differentiation of human 5-HT1B and 5-HT1D receptors. Biol Signals. 3:1994;217-222
24. Potrebic S., Ahn A.H., Skinner K., Fields H.L., Basbaum A.I. Peptidergic nociceptors of both trigeminal and dorsal root ganglia express serotonin 1D receptors: implications for the selective antimigraine action of triptans. J Neurosci. 23:2003;10988-10997
25. Ray B., Wolff H. Experimental studies on headache. Pain-sensitive structures of the head and their significance in headache. Arch Surg. 41:1940;813-856
26. Rebeck G., Maynard K., Hyman B., Moskowitz M. Selective 5-HT1D[alpha] serotonin receptor gene expression in trigeminal ganglia: implications for antimigraine drug development. Proc Natl Acad Sci USA. 91:1994;3666-3669
27. Roon K.I., Olesen J., Diener H.C., Ellis P., Hettiarachchi J., Poole P.H., Christianssen I., Kleinermans D., Kok J.G., Ferrari M.D. No acute antimigraine efficacy of CP-122,288, a highly potent inhibitor of neurogenic inflammation: results of two randomized, double-blind, placebo-controlled clinical trials. Ann Neurol. 47:2000;238-241
28. 1D-receptor immunoreactivities are expressed by trigeminal sensory fibres. Cephalalgia. 22:2002;424-431
29. Stewart M., Napier C.M., Katugampola S.D., McHarg A.D., Wallis R.M. The binding affinity and functional activity of eletriptan and other 5-HT1B/1D agonists at the human recombinant 5-HT1B and 5-HT1D receptors. Br J Pharmacol. 127:1999;93P
30. Storer R.J., Goadsby P.J. Microiontophoretic application of serotonin (5HT)1B/1D agonists inhibits trigeminal cell firing in the cat. Brain. 120:1997;2171-2177
31. Strassman A.M., Mineta Y., Vos B.P. Distribution of fos-like immunoreactivity in the medullary and upper cervical dorsal horn produced by stimulation of dural blood vessels in the rat. J Neurosci. 14:1994;3725-3735
32. Travagli R.A., Williams J.T. Endogenous monoamines inhibit glutamate transmission in the spinal trigeminal nucleus of the guinea-pig. J Physiol (Lond). 491:1996;177-185
33. Wotherspoon G., Priestley J.V. Expression of the 5-HT1B receptor by subtypes of rat trigeminal ganglion cells. Neuroscience. 95:2000;465-471