Thermal unfolding of medium-chain acyl-CoA dehydrogenase and iso(3)valeryl-CoA dehydrogenase: Study of the effect of genetic defects on enzyme stability

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1690, Issue 1, 2004, Pages 22-32

  Nasser, Ibrahim ^a   Mohsen, Al Walid ^b   Jelesarov, Ilian ^c   Vockley, Jerry ^b   MacHeroux, Peter ^d   Ghisla, Sandro ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b MAYO CLINIC COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d JACOBS UNIVERSITY BREMEN   (Germany)

Author keywords

2 aza iC5 CoA; 2 aza isovaleryl CoA; Acyl CoA dehydrogenase; Conformational disease; Enzyme stability

Indexed keywords

MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE;

ARTICLE; BINDING AFFINITY; ENZYME STABILITY; GENE MUTATION; GENETIC DISORDER; MELTING POINT; PHENOTYPE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THERMOSTABILITY; WILD TYPE;

ACYL-COA DEHYDROGENASE; ENZYME STABILITY; HEAT; ISOVALERYL-COA DEHYDROGENASE; MODELS, MOLECULAR; MUTATION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PROTEIN BINDING; PROTEIN FOLDING;

EID: 4344698067     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2004.04.008     Document Type: Article

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