The roles of threonine-136 and glutamate-137 of human medium chain Acyl- CoA dehydrogenase in FAD binding and peptide folding using site-directed mutagenesis: Creation of an FAD-dependent mutant, T136D

Archives of Biochemistry and Biophysics

Volumn 358, Issue 1, 1998, Pages 49-57

  Saijo, Takahiko ^a,b   Kim, Jung Ja P ^c   Kuroda, Yasuhiro ^b   Tanaka, Kay ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

FAD; Ligand binding; Medium chain acyl CoA dehydrogenase; Protein folding; Site directed mutagenesis

Indexed keywords

FLAVINE ADENINE NUCLEOTIDE; GLUTAMIC ACID; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; RIBOFLAVIN; TETRAMER; THREONINE;

ANIMAL CELL; ARTICLE; ESCHERICHIA COLI; LIGAND BINDING; LIVER MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FOLDING; RAT; SITE DIRECTED MUTAGENESIS;

EID: 18744424611     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1998.0844     Document Type: Article

References (17)

1. Ikeda Y., Dabrowski C., Tanaka K. J. Biol. Chem. 258:1983;1066-1076.
2. Ikeda Y., Okamura-Ikeda K., Tanaka K. J. Biol. Chem. 260:1985;1311-1325.
3. Matsubara Y., Indo Y., Naito E., Ozasa H., Glassberg R., Vockley J., Ikeda Y., Kraus J., Tanaka K. J. Biol. Chem. 27:1989;16321-16331.
4. Indo Y., Yang-Feng T., Glassberg R., Tanaka K. Genomics. 11:1991;609-620.
5. Ikeda Y., Keese S. M., Fenton W. A., Tanaka K. Arch. Biochem. Biophys. 252:1987;662-674.
6. Kelly D. P., Kim J.-J., Billadello J. J., Hainline B. E., Chu T. W., Strauss A. W. Proc. Natl. Acad. Sci. USA. 84:1987;4068-4072.
7. Matsubara Y., Kraus J. P., Ozasa H., Glassberg R., Finocchiaro G., Ikeda Y., Mole J., Rosenberg L. E., Tanaka K. J. Biol. Chem. 262:1987;10104-10108.
8. Saijo T., Welch W. J., Tanaka K. J. Biol. Chem. 269:1994;4401-4408.
9. Saijo T., Tanaka K. J. Biol. Chem. 270:1995;1899-1907.
10. Kim J.-J. P., Wang M., Djordjevic S., Paschke R. New Developments in Fatty Acid Oxidation. 1992;Wiley-Liss, New York. p. 111-126.
11. Kim J.-J. P., Wang M., Paschke R. Proc. Natl. Acad. Sci. USA. 90:1993;7523-7527.
12. Tanaka, K. Indo, Y. 1992, in, New Developments in Fatty Acid Oxidation, Coates, P. M.Tanaka, K. 95, 110, Wiley-Liss, New York.
13. Higuchi R., Krummel B., Saiki R. K. Nucleic Acids Res. 16:1988;7351-7367.
14. Yokota I., Saijo T., Vockley J., Tanaka K. J. Biol. Chem. 267:1992;26004-26010.
15. Tiffany K. A., Roberts D. L., Wang M., Paschke R., Mohsen A.-W., Vockley J., Kim J.-J. P. Biochemistry. 36:1997;8455-8464.
16. Andresen B. S., Bross P., Udvari S., Kirk J., Gray G., Kmoch S., Chamoles N., Knudsen I., Winter V., Wilcken B., Yokota I., Hart K., Packman S., Harpey J. P., Saudubray J. M., Hale D. E., Bolund L., Kølvraa S., Gregersen N. Hum. Mol. Genet. 6:1997;695-707.
17. Bross P., Jaspersen C., Jensen T. G., Andresen B. S., Kristensen M. J., Winter V., Nandy A., Kräutle F., Ghisla S., Bolund L., Kim J.-J., Gregersen N. J. Biol. Chem. 270:1995;10284-10290.