In vitro study on role of Hsp70 expression in DNA damage of human embryonic lung cells exposed to benzo[a]pyrene

Biomedical and Environmental Sciences

Volumn 17, Issue 2, 2004, Pages 144-152

  Gao, Ya Juan ^a   Xiao, Cheng Feng ^a   Chen, Sheng ^a   Wang, Rui Bo ^a   He, Han Zhen ^a   Tanguay, Robert M ^b   Wu, Tang Chun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

Benzo a pyrene; DNA damage; Heat; Hsp70

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; HEAT SHOCK PROTEIN 70;

ARTICLE; CELL DAMAGE; CELL PROTECTION; COMET ASSAY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPATHOGENIC EFFECT; DNA DAMAGE; DNA REPAIR; EMBRYO CELL; FETUS LUNG; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION;

BENZO(A)PYRENE; BLOTTING, WESTERN; CARCINOGENS, ENVIRONMENTAL; CELLS, CULTURED; COMET ASSAY; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; HSP70 HEAT-SHOCK PROTEINS; HUMANS;

EID: 4344692138     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Lindquist, S. and Craig, E. A. (1988). The heat shock Proteins. Ann. Rev. Genet. 22, 631-677.
2. Hightower, L. E. (1991). Heat shock, stress protein, chaperones, and proteotoxicity. Cell 66, 191-197.
3. Tanguay, R. M., Wu, Y., and Khandjian, E. W. (1993). Tissue-specific expression of heat shock stress proteins of the mouse in the absence of stress. Dev. Genet. 14, 112-118.
4. IARC, IARC Monographs on the evaluation of carcinogenic risks to human. Overall evaluations of carcinogenicity: an updating of the IARC Monographs Volumes 1 to 42, Suppl7. Lyon, France: International Agency for Research on Cancer, 1987.
5. Conney, A. H. (1982). Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G. H. A. Clowes; Menorial Lecture. Cancer Res. 42, 4875-4917.
6. Buening, M. K., Wislocki, P. G., Levin, W., Yagi, H., Thakker, D. R., Akagi, H., Koreeda, M., Jerina, D. M., and Conney, A. H. (1978). Tumorigenicity of the optical enantiomers of the diasteriomeric benzo(a)pyrene 7,8-diol-9,10-epoxides in newborne mice: exceptional activity of (+) -7beta,8alpha-dihydroxy-9alpha, 10alpha-epoxy-7, 8, 9, 10- tetrahydrobenzo (a)pyrene. Proc. Natl. Acad. Sci. USA 75, 5358-5361.
7. King, F. W., Wawrzynow, A., Hohfeld, J., and Zylicz, M. (2001). Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53. E. M. B. O. J. 20, 6297-6305.
8. Sepehrnia, B., Paz, I. B., Dasgupta, G., and Momand, J. (1996). Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell. J. Biol. Chem. 271, 15084-15090.
9. Vargas-Roig, L. M., Gago, F. E., Tello, O., Aznar, J. C., and Ciocca, D. R. (1998). Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy. Intern. J. Cancer 79, 468-475.
10. Mehlen, P., Schulze-Osthoff, K., and Arrigo, A. P. (1996). Small stress proteins as novel regulators of apoptosis. Heat shock protein 27 blocks Fas/APO-1- and staurosporine-induced cell death. J. Biol. Chem. 271, 16510-16514.
11. Pinhasi-Kimhi, O., Michalovitz, D., Ben-Zeev, A., and Oren, M. (1986). Specific interactions between the p53 cellular tumour antigen and major heat shock proteins. Nature 320, 182-185.
12. Maron, D. and Ames, B. N. (1983). Revised method for the Salmonella mutagenicity test. Mutat. Res. 113, 173-215.
13. Lowry, O. H, Rosebrought, N. J., Farr, A. L., and Randall, R. J. (1951). Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265-275.
14. Hanelt, S., Helbig, R., Hartmann, A., Lang, M., Seidel, A., and Speit, G. (1997). A comparative investigation of DNA adducts, DNA strand breaks and gene mutations induced by benzo(a)pyrene and (±)-anti-benzo[a]pyrene -7,8 -diol 9,10-oxide in cultured human cells. Mutat. Res. 390, 179-188.
15. Wu, T., Yuan, Y., Wu, Y., He, H., Zhang, G., and Tanguay, R. M. (1998). Presence of antibodies to heat stress proteins in workers exposed to benzene and in patients with benzene poisoning. Cell Stress Chaperones 3, 161-167.
16. Wu, T., Ma, J., Chen, S., Sun, Y., Xiao, C., Gao, Y., Wang, R., Poudrier, J., Dargis, M., Currie, R. W., and Tanguay, R. M. (2001). Association of plasma antibodies against heat stress protein Hsp70 with hypertension and harsh working conditions. Cell Stress Chaperones 6, 394-401.
17. Singh, N. P., McCoy, M. T, and Tice, R. R. (1988). A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res. 175, 184-191.
18. Wu, T., Tanguay, R. M., Wu, Y., He, H., Xu, D., Feng, J., Shi, W., and Zhang, G. (1996). Presence of antibodies to heat stress proteins and its possible significance in workers exposed to high temperature and carbon monoxide. Biomed. Environ. Sci. 9, 370-379.
19. Xiao, C., Chen, S., Li, J., Hai, T., Lu, Q., Sun, E., Wang, R., Tanguay, R. M., and Wu, T. (2002). Association of HSP70 and genotoxic damage in lymphocytes of workers exposed to coke-oven emission. Cell Stress & Chaperones 7, 396-402.
20. Aït-Aïssa, S., Porcher, J. M., Arrigo, A. P., and Lambré, C. (2000). Activation of the hsp70 promotor by environmental inorganic and organic chemicals: relationships with cytotoxicity and lipophilicity. Toxicology 145, 147-157.
21. Vayssier-Taussat, M., Camilli, T., Aron, Y., Meplan, C., Hainaut, P., Polla, B. S., and Weksler, B. (2001). Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses. Am. J. Physiol. Heart Circ. Physiol. 280, H1293-1300.
22. Shi, Y., Mosser, D. D., and Morimoto, R. I. (1998). Molecular chaperones as HSF1-specific transcriptional repressors. Gene & Dev. 12, 654-666.
23. Bartosiewicz, M., Peen, S., and Buckpitt, A. (2001). Application of gene arrays in environmental toxicology: Fingerprints of gene regulation associated with cadmium chloride, benzo[a]pyrene, and trichloroethylene. Environ. Health Perspect 109, 71-74.
24. Beland, F. A. and Poirier, M. C. (1994). DNA adducts and their consequences, in: Tardiff RG, Lohmann PHM and Wogan GN (Eds), Methods to Assess DNA Damage and Repair: Interspecies Comparisons, John Wiley and Sons, Chichester, pp. 29-55.
25. Vaziri, C. and Faller, D. V. (1997). A benzo(a)pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. J. Biol. Chem. 272, 2762-2769.
26. 2-terminal kinase 1 by benzo(a)pyrene. Cancer Res. 58, 2102-2106.
27. Drouin, E. E., Lech, J., and Loechler, E. L. (1995). The major N2-Gua adduct of the (+) -anti-benzo(a)pyrene diol epoxide can be unstable in double-stranded DNA. Biochem. 34, 2251-2259.
28. Speit, G., Hanelt, S., Helbig, R., Seidel, A., and Hartmann, A. (1996). Detection of DNA effects in human cells with the comet assay and their relevance for mutagenesis. Toxicol. Lett. 88, 91-98.
29. Vayssier, M., Banzet, N., François, D., Bellman, K., and Polla, B. S. (1998). Tabacco smoke induces both apoptosis and necrosis in mammalian cells: differential effects of HSP70. Am. J. Physiol. Lung Cell Mol. Physiol. 275, L771-L779.
30. Moseley, P. L. (2000). Exercise, stress, and the immune conversation. Exerc. Sport Sci. Rev. 28, 128-132.