Differential activation of glomeruli in the ferret's main olfactory bulb by anal scent gland odours from males and females: An early step in mate identification

European Journal of Neuroscience

Volumn 20, Issue 4, 2004, Pages 1025-1032

  Woodley, Sarah K ^a   Baum, Michael J ^a  

^a Boston University   (United States)

Author keywords

Accessory olfactory bulb; Atypical glomeruli; c fos; Pheromones; Sex dimorphism; Sexual behaviour

Indexed keywords

ACETYLCHOLINESTERASE; ESTROGEN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ESTROGEN THERAPY; FEMALE; FERRET; HYSTERECTOMY; MALE; MATE CHOICE; MATING; NEUROPIL; NONHUMAN; OLFACTORY BULB; OLFACTORY DISCRIMINATION; PERIANAL GLAND; PRIORITY JOURNAL; SCENT GLAND; SEX DIFFERENCE; VOMERONASAL ORGAN;

ANAL SACS; ANIMALS; FEMALE; FERRETS; MALE; OLFACTORY BULB; PHEROMONES; SEXUAL BEHAVIOR, ANIMAL;

EID: 4344689824     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2004.03571.x     Document Type: Article

References (41)

1. Aroniadou-Anderjaska, V., Zhou, F.M., Priest, C.A., Ennis, M. & Shipley, M.T. (2000) Tonic and synaptically evoked presynaptic inhibition of sensory input to the rat olfactory bulb via GABA (B) heteroreceptors. J. Neurophysiol., 84, 1194-1203.
2. Aungst, J.L., Heyward, P.M., Puche, A.C., Karnup, S.V., Hayar, A., Szabo, G. & Shipley, M.T. (2003) Centre-surround inhibition among olfactory bulb glomeruli. Nature, 426, 623-629.
3. Brown, R. & Macdonald, D. (1985) Social Odours in Mammals. Clarendon Press, Oxford.
4. Clapperton, B., Minot, E. & Crump, D. (1988) An olfactory recognition system in the ferret Mustela furo L. (Carnivora: Mustelidae). Anim. Behav., 36, 541-553.
5. Coolen, L.M. & Wood, R.I. (1998) Bidirectional connections of the medial amygdaloid nucleus in the Syrian hamster brain: simultaneous anterograde and retrograde tract tracing. J. Comp. Neurol., 399, 189-209.
6. Ennis, M., Zhou, F.M., Ciombor, K.J., Aroniadou-Anderjaska, V., Hayar, A., Borrelli, E., Zimmer, L.A., Margolis, F. & Shipley, M.T. (2001) Dopamine D2 receptor-mediated presynaptic inhibition of olfactory nerve terminals. J. Neurophysiol., 86, 2986-2997.
7. Greer, C.A., Stewart, W.B., Teicher, M.H. & Shepherd, G.M. (1982) Functional development of the olfactory bulb and a unique glomerular complex in the neonatal rat. J. Neurosci., 2, 1744-1759.
8. Halpern, M. & Martinez-Marcos, A. (2003) Structure and function of the vomeronasal system: an update. Prog. Neurobiol., 70, 245-318.
9. Hedreen, J., Bacon, S. & Price, D. (1985) A modified histochemical technique to visualize acetylcholinesterase-containing axons. J. Histochem. Cytochem., 33, 134-140.
10. Johnson, B.A., Woo, C.C. & Leon, M. (1998) Spatial coding of odorant features in the glomerular layer of the rat olfactory bulb. J. Comp. Neurol., 393, 457-471.
11. Johnston, R.E. (1983) Chemical signals and reproductive behavior. In Vandenbergh, J.G. (Ed.), Pheromones and Reproduction in Mammals. Academic Press, New York, pp. 3-37.
12. Juilfs, D., Fulle, H., Zhao, A., Houslay, M., Garbers, D. & Beavo, J. (1997) A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway. Proc. Natl Acad. Sci. USA, 94, 3388-3395.
13. Kelliher, K.R. & Baum, M.J. (2001) Nares occlusion eliminates heterosexual partner selection without disrupting coitus in ferrets of both sexes. J. Neurosci., 21, 5832-5840.
14. Kelliher, K.R. & Baum, M.J. (2002) Effect of sex steroids and coital experience on ferrets' preference for the smell, sight and sound of conspecifics. Physiol. Behav., 76, 1-7.
15. Kelliher, K.R., Chang, Y.M., Wersinger, S.R. & Baum, M.J. (1998) Sex difference and testosterone modulation of pheromone-induced Neuronal Fos in the Ferret's main olfactory bulb and hypothalamus. Biol. Reprod, 59, 1454-1463.
16. Keverne, E.B. (1999) The vomeronasal organ. Science, 286, 716-720.
17. Kevetter, G.A. & Winans, S.S. (1981) Connections of the corticomedial amygdala in the golden hamster. II. Efferents of the 'olfactory amygdala'. J. Comp. Neurol., 197, 99-111.
18. Leypold, B., Yu, C., Leinders-Zufall, T., Kim, M., Zufall, F. & Axel, R. (2002) Altered sexual and social behaviors in trp2 mutant mice. Proc. Natl Acad. Sci. USA, 99, 6842-6845.
19. Lin, W., Arellano, J., Slotnick, B. & Restrepo, D. (2004) Odors detected by mice deficient in cyclic nucleotide-gated channel subunit A2 stimulate the main olfactory system. J. Neurosci., 24, 3703-3710.
20. Lin, D. & Katz, L. (2003) Main olfactory bulb detection of social recognition cues present in mouse urine. Soc. Neurosci. Abstr. Society for Neuroscience, Washington, DC. Program No. 340.11.
21. Linster, C., Johnson, B.A., Yue, E., Morse, A., Xu, Z., Hingco, E.E., Choi, Y., Choi, M., Messiha, A. & Leon, M. (2001) Perceptual correlates of neural representations evoked by odorant enantiomers. J. Neurosci., 21, 9837-9843.
22. Luo, M., Fee, M. & Katz, L. (2003) Encoding pheromonal signals in the accessory olfactory bulb of behaving mice. Science, 299, 1196-1201.
23. Ma, D., Allen, N.D., Van Bergen, Y.C., Jones, C.M., Baum, M.J., Keverne, E.B. & Brennan, P.A. (2002) Selective ablation of olfactory receptor neurons without functional impairment of vomeronasal receptor neurons in OMP-ntr transgenic mice. Eur. J. Neurosci., 16, 2317-2323.
24. Mombaerts, P., Wang, F., Dulac, C., Chao, S.K., Nemes, A., Mendelsohn, M., Edmondson, J. & Axel, R. (1996) Visualizing an olfactory sensory map. Cell, 87, 675-686.
25. Rubin, B.D. & Katz, L.C. (1999) Optical imaging of odorant representations in the mammalian olfactory bulb. Neuron, 23, 499-511.
26. Scalia, F. & Winans, S.S. (1975) The differential projections of the olfactory bulb and accessory olfactory bulb in mammals. J. Comp. Neurol., 161, 31-55.
27. Schaefer, M., Finger, T. & Restrepo, D. (2001a) Variability of position of the P2 glomerulus within a map of the mouse olfactory bulb. J. Comp. Neurol., 436, 351-362.
28. Schaefer, M., Yamazaki, K., Osada, K., Restrepo, D. & Beauchamp, G. (2002) Olfactory fingerprints for major histocompatibility complex-determined body odors II: relationship among odor maps, genetics, odor composition, and behavior. J. Neurosci., 22, 9513-9521.
29. Schaefer, M., Young, D. & Restrepo, D. (2001b) Olfactory fingerprints for major histocompatibility complex-determined body odors. J. Neurosci., 21, 2481-2487.
30. Shinoda, K., Shiotani, Y. & Osawa, Y. (1989) 'Necklace olfactory glomeruli' form unique components of the rat primary olfactory system. J. Comp. Neurol., 284, 362-373.
31. Shipley, M. & Ennis, M. (1996) Functional organization of olfactory system. J. Neurobiol., 30, 123-176.
32. Stowers, L., Holy, T., Meister, M., Dulac, C. & Koentges, G. (2002) Loss of sex discrimination and male-male aggression in mice deficient for TRP2. Science, 295, 1493-1500.
33. Wachowiak, M. & Cohen, L.B. (2001) Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron, 32, 723-735.
34. Wersinger, S.R. & Baum, M.J. (1996) The temporal pattern of mating-induced immediate-early gene product immunoreactivity in LHRH and non-LHRH neurons of the estrous ferret forebrain. J. Neuroendocrinol., 8, 345-359.
35. Wersinger, S.R. & Baum, M.J. (1997) Sexually dimorphic processing of somatosensory and chemosensory inputs to forebrain luteinizing hormone-releasing hormone neurons in mated ferrets. Endocrinology, 138, 1121-1129.
36. Weruaga, E., Brinon, J.G., Porteros, A., Arevalo, R., Aijon, J. & Alonso, J.R. (2001) A sexually dimorphic group of atypical glomeruli in the mouse olfactory bulb. Chem. Senses, 26, 7-15.
37. Woodley, S.K. & Baum, M. (2003) Effects of sex hormones and gender on attraction thresholds for volatile anal scent gland odors in ferrets. Horm. Behav., 44, 110-118.
38. Xu, F., Greer, C. & Shepherd, G. (2000) Odor maps in the olfactory bulb. J. Comp. Neurol., 422, 489-495.
39. Xu, F., Kida, I., Shaefer, M., Restrepo, D., Rothman, D., Hyder, F. & Shepherd, G. (2003) Comparison of responses in the mouse main and accessory olfactory bulbs revealed by FMRI. Soc. Neurosci. Abstr. Society for Neuroscience, Washington, DC. Program No. 340.12.
40. Yamazaki, K., Beauchamp, G.K., Egorov, I.K., Bard, J., Thomas, L. & Boyse, E.A. (1983) Sensory distinction between H-2b and H-2bm1 mutant mice. Proc. Natl Acad. Sci. USA, 80, 5685-5688.
41. Zheng, L., Ravel, N. & Jourdan, F. (1987) Topography of centrifugal acetylcholinesterase-positive fibres in the olfactory bulb of the rat: evidence for original projections in atypical glomeruli. Neuroscience, 23, 1083-1093.