Chymase is activated in the pulmonary inflammation and fibrosis induced by paraquat in hamsters

Tohoku Journal of Experimental Medicine

Volumn 203, Issue 4, 2004, Pages 287-294

  Orito, Kensuke ^b   Suzuki, Yuko ^b   Matsuda, Hiroshi ^a   Shirai, Mitsuyuki ^b   Akahori, Fumiaki ^b  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b AZABU UNIVERSITY   (Japan)

Author keywords

ACE; Chymase; Paraquat; Pulmonary fibrosis

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN I; CHYMASE; DIPEPTIDYL CARBOXYPEPTIDASE; PARAQUAT; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; HAMSTER; LUNG CONGESTION; LUNG FIBROSIS; LUNG HEMORRHAGE; MALE; NONHUMAN; PARAQUAT POISONING; PNEUMONIA; TISSUE DISTRIBUTION; TISSUE INJURY; TISSUE PREPARATION;

ACUTE TOXICITY TESTS; ANIMALS; CHYMASES; CRICETINAE; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; HERBICIDES; MALE; PARAQUAT; PEPTIDYL-DIPEPTIDASE A; PNEUMONIA; PULMONARY FIBROSIS; SERINE ENDOPEPTIDASES; TOXICITY TESTS, CHRONIC;

EID: 4344685222     PISSN: 00408727     EISSN: None     Source Type: Journal    
DOI: 10.1620/tjem.203.287     Document Type: Article

References (30)

1. Akasu, M., Urata, H., Kinoshita, A., Sasaguri, M., Ideishi, M. & Arakawa, K. (1998) Differences in tissue angiotensin II-forming pathways by species and organs in vitro. Hypertension, 32, 514-520.
2. Balcells, E., Meng, Q.C., Johnson, W.H., Jr., Oparil, S. & Dell'Italia, L.J. (1997) Angiotensin II formation from ACE and chymase in human and animal hearts: methods and species considerations. Am. J. Physiol., 273, H1769-H1774.
3. Berisha, H.I., Pakbaz, H., Absood, A. & Said, S.I. (1994) Nitric oxide as a mediator of oxidant lung injury due to paraquat. Proc. Natl. Acad. Sci. U.S. A., 91, 7445-7449.
4. Bruyndonckx, R.B., Meulemans, A.I., Sabbe, M.B., Kumar, A.A. & Delooz, H.H. (2002) Fatal intentional poisoning cases admitted to the University Hospitals of Leuven, Belgium from 1993 to 1996. Eur. J. Emerg. Med., 9, 238-243.
5. Bus, J.S., Aust, S.D. & Gibson, J.E. (1974) Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity. Biochem. Biophys. Res. Commun., 58, 749-755.
6. Butler, C., 2nd. (1975) Pulmonary interstitial fibrosis from paraquat in the hamster. Arch. Pathol., 99, 503-507.
7. Harsanyi, L., Nemeth, A. & Lang, A. (1987) Paraquat (gramoxone) poisoning in south-west Hungary, 1977-1984. Toxicological and histopathological aspects of group intoxication cases. Am. J. Forensic. Med. Pathol., 8, 131-134.
8. Hollinger, M.A., Patwell, S.W., Zuckerman, J.E., Gorin, A.B., Parsons, G. & Giri, S.N. (1980) Effect of paraquat on serum angiotensin converting enzyme. Am. Rev. Respir. Dis., 121, 795-798.
9. Horiuchi, M., Fujimura, K., Terashima, T. & Iso, T. (1982) Method for determination of angiotensin-converting enzyme activity in blood and tissue by high-performance liquid chromatography. J. Chromatogr, 233, 123-130.
10. Hsu, H.H., Chang, C.T. & Lin, J.L. (2003) Intravenous paraquat poisoning-induced multiple organ failure and fatality - a report of two cases. J. Toxicol. Clin. Toxicol., 41, 87-90.
11. Hwang, K.Y., Lee, E.Y. & Hong, S.Y. (2002) Paraquat intoxication in Korea. Arch. Environ. Health, 57, 162-166.
12. Jaeger, A., Sauder, P. & Jacques, K. (1995) Mechanisms of Paraquat Toxicity and Therapeutic Implications. Paraquat poisoning Mechanisms, Prevention, Treatment Ed. Bismuth-C, Hall-AH, pp. 141-159.
13. Jin, D., Takai, S., Yamada, M., Sakaguchi, M., Yao, Y. & Miyazaki, M. (2001) Possible roles of cardiac chymase after myocardial infarction in hamster hearts. Jpn. J. Pharmacol., 86, 203-214.
14. Kofford, M.W., Schwartz, L.B., Schechter, N.M., Yager, D.R., Diegelmann, R.F. & Graham, M.F. (1997) Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide. J. Biol. Chem., 272, 7127-7131.
15. Kokubo, T., Takahashi, M., Furukawa, F., Nagano, K. & Hayashi, Y. (1984) Pathogenesis of paraquat-induced pulmonary hemorrhage in hamsters with special reference to arterial constriction. Acta. Pathol. Jpn., 34, 41-46.
16. Lowry, O.H., Rosebrough, N.J., Farr, A.L. & Randall, R.J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193, 265-275.
17. Lugo-Vallin, N., Maradei-Irastorza, I., Pascuzzo-Lima, C., Ramirez-Sanchez, M. & Montesinos, C. (2003) Thirty-five cases of S-carboxymethyl-cysteine use in paraquat poisoning. Vet. Hum. Toxicol., 45, 45-46.
18. Marshall, R.P., McAnulty, R.J. & Laurent, G.J. (2000) Angiotensin II is mitogenic for human lung fibroblasts via activation of the type 1 receptor. Am. J. Respir. Crit. Care Med., 161, 1999-2004.
19. Masaoka, T., Akahori, F., Ikeda, J. & Arai, S. (1989) Effect of paraquat on serum and lung angiotensin I converting enzyme (AICE) activity in beagle dogs. Vet. Hum. Toxicol., 31, 430-435.
20. Mitani, Y., Ueda, M., Maruyama, K., Shimpo, H., Kojima, A., Matsumura, M., Aoki, K. & Sakurai, M. (1999) Mast cell chymase in pulmonary hypertension. Thorax., 54, 88-90.
21. Nagata, T., Kono, I., Masaoka, T. & Akahori, F. (1992) Acute toxicological studies on paraquat: pathological findings in beagle dogs following single subcutaneous injections. Vet. Hum. Toxicol., 34, 105-112.
22. Saarinen, J., Kalkkinen, N., Welgus, H.G. & Kovanen, P.T. (1994) Activation of human interstitial procollagenase through direct cleavage of the Leu83-Thr84 bond by mast cell chymase. J. Biol. Chem., 269, 18134-18140.
23. Sakaguchi, N., Takai, S., Jin, D. & Miyazaki, M. (2002) Effects of specific chymase inhibitor, NK3201, on bleomycin-induced pulmonary fibrosis in hamsters. Jpn. J. Pharmacol., 88, 184P.
24. Shiota, N., Okunishi, H., Fukamizu, A., Sakonjo, H., Kikumori, M., Nishimura, T., Nakagawa, T., Murakami, K. & Miyazaki, M. (1993) Activation of two angiotensin-generating systems in the balloon-injured artery. FEBS Lett., 323, 239-242.
25. Stephens, B.G. & Moormeister, S.K. (1997) Homicidal poisoning by paraquat. Am. J. Forensic Med. Pathol., 18, 33-39.
26. Tachikawa, H., Kodama, M., Hui, L., Yoshida, T., Hayashi, M., Abe, S., Kashimura, T., Kato, K., Hanawa, H., Watanabe, K., Nakazawa, M. & Aizawa, Y. (2003) Angiotensin II type 1 receptor blocker, valsartan, prevented cardiac fibrosis in rat cardiomyopathy after autoimmune myocarditis. J. Cardiovasc. Pharmacol., 41, Suppl. 1, S105-S110.
27. Tinoco, R., Parsonnet, J. & Halperin, D. (1993) Paraquat poisoning in southern Mexico: a report of 25 cases. Arch. Environ. Health, 48, 78-80.
28. Toner, P.G., Vetters, J.M., Spilg, W.G. & Harland, W.A. (1970) Fine structure of the lung lesion in a case of paraquat poisoning. J. Pathol., 102, 182-185.
29. Winchester, J. (1995) History of Paraquat Intoxication. Paraquat poisoning Mechanisms, Prevention, Treatment Ed. Bismuth-C, Hall-AH, pp. 1-16.
30. Yasaka, T., Okudaira, K., Fujito, H., Matsumoto, J., Ohya, I. & Miyamoto, Y. (1986) Further studies of lipid peroxidation in human paraquat poisoning. Arch. Intern. Med., 146, 681-685.