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Head E, Lott IT. Down syndrome and beta amyloid deposition. Curr Opin Neurol 2004; 17:95-100. Summarizes research on the amyloid hypothesis in dementia in persons with Down syndrome.
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Prasher VP. Weight loss in adults with Down syndrome and with dementia in Alzheimer's disease. Res Dev Disabil 2004; 25:1-7. Weight loss appears to be associated with dementia in persons with Down syndrome as has also been reported for the general population.
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Urv TK, Zigman WB, Silverman W. Maladaptive behaviors related to adaptive decline in aging adults with mental retardation. Am J Ment Retard 2004; 108:327-339. Given traditional assessment approaches and measures have been demonstrated to be less than useful in assessing dementia and other declines, this study offers evidence for the use of increases in maladaptive behaviors as a marker for decline.
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Heller T, Hsieh K, Rimmer JH. Fitness and health education program for Down syndrome. Am J Ment Retard 2004; 109:174-185.
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