Humming-induced release of nasal nitric oxide for assessment of sinus obstruction in allergic rhinitis: Pilot study

European Journal of Clinical Investigation

Volumn 34, Issue 8, 2004, Pages 555-560

  Maniscalco, M ^a,b,e   Sofia, M ^b   Weitzberg, E ^c   De Laurentiis, G ^b   Stanziola, A ^b   Rossillo, V ^d,e   Lundberg, J O ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d MONALDI HOSPITAL   (Italy)

^e Karolinska Institutet ^*  (Italy)

Author keywords

Allergic rhinitis; Asthma; Exhaled; Humming; Nitric oxide; Polyposis; Sinusitis

Indexed keywords

NITRIC OXIDE;

AIRWAY OBSTRUCTION; ALLERGIC RHINITIS; ANAMNESIS; ARTICLE; BREATHING PATTERN; CHEMOLUMINESCENCE; ENDOSCOPY; EXHALATION; HUMAN; MAJOR CLINICAL STUDY; NOSE BREATHING; PARANASAL SINUS; PARANASAL SINUS DISEASE; PERENNIAL RHINITIS; PHONATION; PILOT STUDY; PRIORITY JOURNAL; RISK FACTOR; SINUSITIS;

ACOUSTIC STIMULATION; ADOLESCENT; ADULT; EXHALATION; FEMALE; HUMANS; MALE; MIDDLE AGED; NASAL OBSTRUCTION; NITRIC OXIDE; NOSE; PARANASAL SINUSES; PILOT PROJECTS; RHINITIS, ALLERGIC, PERENNIAL; SINUSITIS;

EID: 4344653017     PISSN: 00142972     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2004.01384.x     Document Type: Article

References (33)

1. Lanza DC, Kennedy DW. Adult rhinosinusitis defined. Otolaryngol Head Neck Surg 1997;117:S1-7.
2. Kaliner MA, Osguthorpe JD, Fireman P, Anon J, Georgitis J, Davis ML et al. Sinusitis: bench to bedside. Current findings, future directions. J Allergy Clin Immunol 1997;99:S829-48.
3. Ray NF, Baraniuk JN, Thamer M, Rinehart CS, Gergen PJ, Kaliner M et al. Healthcare expenditures for sinusitis in 1996: contributions of asthma, rhinitis, and other airway disorders. J Allergy Clin Immunol 1999;103:408-14.
4. Kaliner M. Medical management of sinusitis. Am J Med Sci 1998;316:21-8.
5. Wagenmann M, Naclerio RM. Anatomic and physiologic considerations in sinusitis. J Allergy Clin Immunol 1992;90:419-23.
6. Alving K, Weitzberg E, Lundberg JM. Increased amount of nitric oxide in exhaled air of asthmatics. Eur Resp J 1993;6:1368-70.
7. Nathan C, Xie Q-W. Nitric oxide synthases. roles, tolls, and controls. Cell 1994;78:915-8.
8. Lundberg JO, Farkas-Szallasi T, Weitzberg E, Rinder J, Lidholm J, Anggard A et al. High nitric oxide production in the human paranasal sinuses. Nature Med 1995;1:370-3.
9. Lundberg JO, Weitzberg E. Nasal nitric oxide in man. Thorax 1999;54:947-52.
10. Furukawa K, Harrison DG, Saleh D, Shennib H, Chagnon FP, Giaid A. Expression of nitric oxide synthase in the human nasal mucosa. Am J Resp Crit Care Med 1996;153:847-50.
11. Weitzberg E, Lundberg JO. Humming greatly increases nasal nitric oxide. Am J Crit Care Med 2002;166:144-5.
12. Lundberg JO, Maniscalco M, Sofia M, Lundblad J, Weitzberg E. Humming, nitric oxide and paranasal obstruction. JAMA 2003;289:302-3.
13. D'Amato G, Lobefalo G. Allergenic pollens in the southern Mediterranean area. J Allergy Clin Immunol 1989;83:116-22.
14. Palm JP, Graf P, Lundberg JO, Alving K. Characterization of exhaled nitric oxide: introducing a new reproducible method for nasal nitric oxide measurement. Eur Resp J 2000;16:236-41.
15. Maniscalco M, Weitzberg E, Sundberg J, Sofia M, Lundberg JO. Assessment of nasal and sinus nitric oxide output using single-breath humming exhalations. Eur Respir J 2003;22:323-9.
16. Percodani J, Serrano E, Didier A. How to explore the nose in daily practice. In: Walleart B, Chenez P, Godard P. The Nose and Lung Diseases. European Respiratory Monograph 2000;6:16-24.
17. Paulsson B, Dolata J, Larsson I, Ohlin P, Lindberg S. Paranasal sinus ventilation in healthy subjects and in patients with sinus disease evaluated with the 133-xenon washout technique. Ann Otol Rhinol Laryngol 2001;110:667-74.
18. Paulsson B, Dolata J, Lindberg S, Ohlin P. Factors influencing 133-xenon washout in a nose-sinus model. Clin Physiol 2001;21:246-52.
19. Naclerio RM, deTineo ML, Baroody FM. Ragweed allergic rhinitis and the paranasal sinuses. A computed tomographic study. Arch Otolaryngol Head Neck Surg 1997;123:193-6.
20. Mucha SM, Baroody FM. Sinusitis update. Curr Opin Allergy Clin Immunol 2003;3:33-8.
21. Arango P, Kountakis SE. Significance of computed tomography pathology in chronic rhinosinusitis. Laryngoscope 2001;111:1779-82.
22. Emanuel IA, Shah SB. Chronic rhinosinusitis: allergy and sinus computed tomography relationships. Otolaryngol Head Neck Surg 2000;123:687-91.
23. Deja M, Busch T, Bachmann S, Riskowski K, Campean V, Wiedmann B et al. Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis. Am J Respir Crit Care Med 2003;168:281-6.
24. Santamaria F, Maniscalco M, de Laurentiis G, Di Benedetto L, Weitzberg E, Sofia M et al. Lack of nasal nitric oxide increase by humming in primary ciliary dyskinesia. Eur Respir J 2003;22(Suppl. 45):384S.
25. Colantonio D, Brouillette L, Parikh A, Scadding GK. Paradoxical low nasal nitric oxide in nasal polyposis. Clin Exp Allergy 2002;32:698-701.
26. Arnal JF, Flores P, Kami J, Murris Espin M, Brenont F, Rasto M et al. Nasal nitric oxide concentration in paranasal sinus inflammatory disease. Eur Respir J 1999;13:307-12.
27. Ganjian E, Gannon PJ, Fliegelman L, Lawson W. Nasal obstruction: an alternative to osteomeatal complex dysfunction in sinus disease. Laryngoscope 1999;109:1848-51.
28. Palm JP, Alving K, Lundberg JO. Characterization of airway nitric oxide in allergic rhinitis. The effect of intranasal administration of L-NAME. Allergy 2003;58:885-92.
29. Maniscalco M, Sofia M, Carratù L, Higenbottam T. Effect of nitric oxide inhibition on nasal airway resistance after nasal allergen challenge in allergic rhinitis. Eur J Clin Invest 2001;31:462-6.
30. Henriksen AH, Sue-Chu M, Lingaas Holmen T, Langhammer A, Bjermer L. Exhaled and nasal NO levels in allergic rhinitis: relation to sensitization, pollen season and bronchial hyperresponsiveness. Eur Respir J 1999;13:301-6.
31. Kharitonov SA, Rajakulasingam K, O'Connor B, Durham SR, Barnes PJ. Nasal nitric oxide is increased in patients with asthma and allegic rhinitis and may be modulated by nasal glucocorticosteroids. J Allergy Clin Immunol 1997;99:58-64.
32. Martin U, Briden K, Devoy M, Howarth P. Increased levels of exhaled nitric oxide during nasal and oral breathing in subjects with seasonal rhinitis. J Allergy Clin Immunol 1996;97:768-72.
33. Arnal JF, Didier A, Rami J, M'Rini C, Charlet JP, Serrano E et al. Nasal nitric oxide is increased in allergic rhinitis. Clin Exp Allergy 1997;27:358-62.