Decreased serum leptin levels during prolonged high altitude exposure

European Journal of Applied Physiology

Volumn 92, Issue 3, 2004, Pages 249-253

  Zaccaria, Marco ^a   Ermolao, Andrea ^a   Bonvicini, Piero ^b   Travain, Giuseppe ^a   Varnier, Maurizio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

Body mass; Catecholamines; High altitude; Insulin; Leptin

Indexed keywords

ADRENALIN; INSULIN; LEPTIN; NORADRENALIN;

ADRENALIN URINE LEVEL; ADULT; ALTITUDE; ALTITUDE DISEASE; ARTICLE; BLOOD SAMPLING; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOCRINE FUNCTION; ENERGY BALANCE; HORMONAL REGULATION; HORMONE ACTION; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; MALE; METABOLIC PARAMETERS; NORADRENALIN URINE LEVEL; NORMAL HUMAN; PRIORITY JOURNAL; SCORING SYSTEM; SYMPTOMATOLOGY;

EID: 4344651155     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-004-1070-0     Document Type: Article

References (29)

1. Boden G, Chen X, Kolaczynski JW, Polansky M (1990 Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects. J Clin Invest 100:1107-1113
2. Brooks GA, Butterfield GE, Wolfe RR, Groves BM, Mazzeo RS, Sutton JR, Wolfel EE, Reeves JT (1991) Increased dependence on blood glucose after acclimatization to 4,300 m. J Appl Physiol 70:919-927
3. Butterfield GE, Gates J, Fleming S, Brooks GA, Sutton JR, Reeves JT (1992) Increased energy intake minimizes weight loss in men at high altitude. J Appl Physiol 72:1741-1748
4. Cammisotto PG, Bukowiecki LJ (2002) Mechanisms of leptin secretion from white adipocytes. Am J Physiol Cell Physiol 283: C244-250
5. Considine RV, Sinha MK, Heiman ML, Kriaciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, McKee LJ, Bauer TL, Caro JF (1996) Serum immunoreactive leptin concentrations in normal-weight and obese humans. N Engl J Med 334:292-295
6. Eriksson BM, Gustafsson S, Persson BA (1983) Determination of catecholamines in urine by ion-exchange liquid chromatography with electrochemical detection. J Chromatogr 278:255-263
7. Fritsche A, Wahl HG, Metzinger E, Renn W, Kellerer M, Haring H, Stumvoll M (1998) Evidence for inhibition of leptin secretion by catecholamines in man. Exp Clin Endocrinol Diabetes 106:415-418
8. Kayser B (1992) Nutrition and high altitude exposure Int J Sports Med 13: S129-132
9. Kolaczynski JW, Considine RV, Ohannesian J, Marco C, Opentanova I, Nyce MR, Myint M, Caro JF (1996a) Responses of leptin to short-term fasting and refeeding in humans. Diabetes 45:1511-1515
10. Kolaczynski JW, Nyce MR, Considine RV, Boden G, Nolan JJ, Henry R, Mudaliar SR, Olefsky J, Caro JF (1996b) Acute and chronic effects of insulin on leptin production in humans: studies in vivo and in vitro. Diabetes 45:699-701
11. Kolaczynski JW, Ohannesian J, Considine RV, Marco C, Caro JF (1996c) Responses of leptin to short-term and prolonged overfeeding in humans. J Clin Endocrinol Metab 81:4162-4165
12. Malmstrom R, Taskinen MR, Karonen SL, Yki-Jarvinen H (1996) Insulin increases plasma leptin concentrations in normal subjects and patients with NIDDM. Diabetologia 39:993-996
13. Mazzeo RS, Wolfel EE, Butterfield GE, Reeves JT (1994) Sympathetic response during 21 days at high altitude (4,300 m) as determined by urinary and arterial catecholamines. Metabolism 43:1226-1232
14. Mazzeo RS, Brooks GA, Butterfield GE, Podolin DA, Wolfel EE, Reeves JT (1995) Acclimatization to high altitude increase muscle sympathetic activity both at rest and during exercise. Am J Physiol 269:R201-207
15. Piccoli A, Piazza P, Noventa D, Pillon L, Zaccaria M (1996) A new method for monitoring high altitude by bioimpedance analysis. Med Sci Sports Exerc 28:1517-1522
16. Pinkney JH, Coppack SW, Mohamed-Ali V (1998) Effect of isoprenaline on plasma leptin and lipolysis in humans. Clin Endocrinol 48:407-411
17. Ponchia A, Noventa D, Bertaglia M, Carretta R, Zaccaria M, Miraglia G, Pascotto P, Buja G (1994) Cardiovascular neural regulation during and after prolonged high altitude exposure. Eur Heart J 15:1463-1469
18. Roach RC (1993) The Lake Louise acute mountain sickness scoring system. In: Sutton JR, Coates G, Houston CS (eds) Hypoxia and molecular medicine. Queen City Printers, Burlington, Vt., pp 272-274
19. Rostrup, M (1998) Catecholamines, hypoxia and high altitude. Acta Physiol Scand 162:389-399
20. Rowell LB, Johnson DG, Chase PB, Comess KA, Seals DR (1989) Hypoxemia raises muscle sympathetic activity but not norepinephrine in resting humans. J Appl Physiol 66:1736-1743
21. Sawhney RC, Malhotra AS, Singh T (1991) Glucoregulatory hormones in man at high altitude. Eur J Appl Physiol 62:286-291
22. Scriba D, Aprath-Husmann I, Blum WF, Hauner H (2000) Catecholamines suppress leptin release from in vitro differentiated subcutaneous human adipocytes in primary culture via beta1- and beta2-adrenergic receptors. Eur J Endocrinol 143:439-445
23. Simsch C, Lormes W, Petersen KG, Baur S, Liu Y, Hackney AC, Lehmann M, Steinacker JM (2002) Training intensity influences leptin and thyroid hormones in highly trained rowers. Int J Sports Med 23:422-427
24. Tschöp M, Strasburger CJ, Hartmann G, Biollaz J, Bartsch P (1998) Raised leptin concentrations at high altitude associated with loss of appetite. Lancet 352:1119-1120
25. Ward MP, Milledge JS, West JB (eds) (1995) High altitude medicine and physiology. Chapman & Hall Medical, London
26. Westerterp KR (2001) Energy and water balance at high altitude. News Physiol Sci 16:134-137
27. Westerterp KR, Kayser B, Wouters L, Le-Trong JL, Richalet JP (1994) Energy balance at high altitude of 6,542m. J Appl Physiol 77:862-866
28. Young PM, Rose MS, Sutton JR, Green HJ, Cymerman A, Houston CS (1989) Operation Everest II: plasma lipid and hormonal responses during a simulated ascent of Mt. Everest. J Appl Physiol 66:1430-1435
29. Zaccaria M, Ermolao A, Roi GS, Englaro P, Tegon G, Varnier M (2002) Leptin reduction after endurance races differing in duration and energy expenditure. Eur J Appl Physiol 87:108-111