Editorial: Adrenal replacement therapy: Time for an inward look to the medulla?

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 8, 2004, Pages 3677-3678

  Stewart, Paul M ^a  

^a UNIVERSITY DEPARTMENT OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; ANDROGEN; CORTISONE; FLUDROCORTISONE; GLUCAGON; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOSE; GROWTH HORMONE; HYDROCORTISONE; INSULIN; MINERALOCORTICOID; NORADRENALIN; PRASTERONE; RADIOISOTOPE; THYROID HORMONE;

ADDISON DISEASE; ADRENAL CORTEX INSUFFICIENCY; ADRENAL FUNCTION; ADRENAL INSUFFICIENCY; ADRENAL MEDULLA; ADRENALECTOMY; ADRENALIN BLOOD LEVEL; BODY MASS; BONE DENSITY; BONE MINERAL; CHROMAFFIN SYSTEM; CONGENITAL ADRENAL HYPERPLASIA; EDITORIAL; EXERCISE TEST; FEVER; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; GROWTH HORMONE DEFICIENCY; GROWTH RETARDATION; HORMONE DEFICIENCY; HORMONE METABOLISM; HORMONE SUBSTITUTION; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPERANDROGENISM; HYPOGLYCEMIA; HYPOPITUITARISM; ISOTOPE TRACING; MAJOR SURGERY; METABOLISM; MORTALITY; OBESITY; PERFORMANCE; PRIORITY JOURNAL; SEX DIFFERENCE; SHORT STATURE; STRESS; TREATMENT FAILURE; ANIMAL; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; NOTE; PATHOPHYSIOLOGY;

ADRENAL HYPERPLASIA, CONGENITAL; ADRENAL INSUFFICIENCY; ADRENAL MEDULLA; ANIMALS; GLUCOCORTICOIDS; HORMONE REPLACEMENT THERAPY; HUMANS;

EID: 4344639790     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-1078     Document Type: Editorial

References (18)

1. Arlt W, Allolio B 2003 Adrenal insufficiency. Lancet 361:1881-1893
2. Stewart PM 2002 The adrenal cortex. In: Larsen PR, Kronenberg H, Melmed S, Polonsky K, eds. Williams textbook of endocrinology, Ch. 14, section 4, 10th ed. Philadelphia: Saunders (Elsevier); 491-551
3. Moore JS, Monson JP, Kaltsas G, Putignano P, Sheppard MC, Besser GM, Taylor NF, Stewart PM 1999 Modulation of 11β-hydroxysteroid dehydrogenase isozymes by growth hormone and insulin-like growth factor: in vivo and in vitro studies. J Clin Endocrinol Metab 84:4172-4177
4. Plumpton FS, Besser GM 1969 The adrenocortical response to surgery and insulin-induced hypoglycaemia in corticosteroid-treated and normal subjects. Brit J Surg 56:216-219
5. Salem M, Tanish RE, Bromberg J, Loriaux DL, Chernow B 1994 Peri-operative glucocorticoid coverage: a reassessment 42 years after emergence of a problem. Annal Surg 4:416-425
6. Cooper MS, Stewart PM 2003 Corticosteroid insufficiency in acutely ill patients. New Engl J Med 348:727-734
7. 2002 Consensus statement on 21-hydroxylase deficiency from the Lawson Wilkins Pediatric Endocrine Society and the European Society for Paediatric Endocrinology. J Clin Endocrinol Metab 87:4048-4053
8. Weise M, Drinkard B, Mehlinger SL, Holzer SM, Eisenhofer G, Charmandari E, Chrousos GP, Merke DP Stress dose of hydrocortisone is not beneficial in patients with classical congenital adrenal hyperplasia undergoing short-term high-intensity exercise. J Clin Endocrinol Metab 89:3679-3684
9. Weise M, Mehlinger SL, Drinkard B, Rawson E, Charmandari E, Hiroi M, Eisenhofer G, Yanovski JA, Chrousos GP, Merke DP 2004 Patients with classic congenital adrenal hyperplasia have decreased epinephrine reserve and defective glucose elevation in response to high-intensity exercise. J Clin Endocrinol Metab 89:591-597
10. Tomlinson JW, Walker EA, Bujalska IJ, Draper N, Lavery GG, Cooper MS, Hewison M, Stewart PM, 11β-Hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev, in press
11. Cole TJ, Blendy JA, Monaghan AP, Krieglstein K, Schmid W, Aguzzi R, Fantuzzi G, Hummler E, Unsicker K, Shutz G 1995 Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation. Genes Dev 9:1608-1621
12. Luo X, Ikeda Y, Parker KL 1994 A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77:481-490
13. Merke DP, Chrousos GP, Eisenhofer G, Weise M, Keil MF, Rogol AD, Van Wyk JJ, Bornstein SR 2000 Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency. N Engl J Med 343:1362-1368
14. Wurtman RJ, Axelrod J 1966 Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids. J Biol Chem 241:2301-2305
15. Zuckerman-Levin N, Tiosano D, Eisenhofer G, Bornstein S, Hochberg Z 2001 The importance of adrenocortical glucocorticoids for adrenomedullary and physiological response to stress: a study in isolated glucocorticoid deficiency. J Clin Endocrinol Metab 86:5920-5924
16. Rudman D, Moffitt SD, Fernhoff PM, Blackston RD, Faraj BA 1981 Epinephrine deficiency in hypocorticotropic hypopituitary children. J Clin Endocrinol Metab 53:722-729
17. Swingle WW, Pfiffner JJ, Vars HM, Bott PA, Parkins WM 1933 The function of the adrenal cortical hormone and the cause of death from adrenal insufficiency. Science 77:58-64
18. Marker JC, Hirsch IB, Smith LJ, Parvin CA, Holloszy JO, Cryer PE 1991 Catecholamines in prevention of hypoglycaemia during exercise in humans. Am J Physiol 260:E705-E712