Nitration and functional loss of voltage-gated K+ channels in rat coronary microvessels exposed to high glucose

Diabetes

Volumn 53, Issue 9, 2004, Pages 2436-2442

  Li, Hongwei ^a   Gutterman, David D ^b   Rusch, Nancy J ^b   Bubolz, Aaron ^b   Liu, Yanping ^b,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; EBSELEN; GLUCOSE; NITRATE; NITRIC OXIDE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE; URATE; VOLTAGE GATED POTASSIUM CHANNEL;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; CORONARY BLOOD VESSEL; CORONARY MICROVASCULATURE; GENE; IMMUNOHISTOCHEMISTRY; KV1 GENE; MALE; MICROVASCULATURE; MULTIGENE FAMILY; NITRATION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SCAVENGING SYSTEM; SMOOTH MUSCLE FIBER; VOLTAGE GATED POTASSIUM CHANNEL KV1.2 ALPHA SUBUNIT;

ANIMALS; AZOLES; CORONARY VESSELS; FREE RADICAL SCAVENGERS; GLUCOSE; MALE; MEMBRANE POTENTIALS; MICROCIRCULATION; NITROGEN; ORGANOSELENIUM COMPOUNDS; PATCH-CLAMP TECHNIQUES; PEROXYNITROUS ACID; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; RATS, SPRAGUE-DAWLEY; URIC ACID; VASODILATION;

EID: 4344628116     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.9.2436     Document Type: Article

References (21)

1. Tesfamarian B, Cohen RA: Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am J Physiol 263:H321-H326, 1992
2. Giugliano D, Ceriello A, Paolisso G: Oxidative stress and diabetic vascular complications. Diabetes Care 19:257-267, 1996
3. Gunnett CA, Heistad DD, Faraci FM: Gene-targeted mice reveal a critical role for inducible nitric oxide synthase in vascular dysfunction during diabetes. Stroke 34:2970-2974, 2003
4. Beckman JS, Chen J, Ischiropoulos H, Crow JP: Oxidative chemistry of peroxynitrite. Methods Enzymol 233:229-240, 1994
5. + channel activity in smooth muscle of human coronary arterioles. Circ Res 91:1070-1076, 2002
6. + channels in rat cerebral artery smooth muscle cells. Am J Physiol Heart Circ Physiol 278:H1883-H1890, 2000
7. Li H, Chai Q, Gutterman DD, Liu Y: Elevated glucose impairs cAMP-mediated dilation by reducing Kv channel activity in rat small coronary smooth muscle cells. Am J Physiol Heart Circ Physiol 285:H1213-H1219, 2003
8. 2 sensors, and controversies. News Physiol Sci 17:131-137, 2002
9. Brock MW, Mathes C, Gilly WF: Selective open-channel block of Shaker (Kv1) potassium channels by s-nitrosodithiothreitol (SNDTT). J Gen Physiol 118:113-134, 2001
10. Caouette D, Dongmo C, Berube J, Fournier D, Daleau P: Hydrogen peroxide modulates the Kv1.5 channel expressed in a mammalian cell line. Naunyn Schmiedebergs Arch Pharmacol 368:479-486, 2003
11. + channel current in rat small coronary arteries. Circ Res 89:146-152, 2001
12. + channels in the cerebral microcirculation of genetically hypertensive rats: evidence for their protection against cerebral vasospasm. Circ Res 82:729-737, 1998
13. + channels in rat small cerebral arteries: molecular identity of the functional channels. J Physiol 551:751-763, 2003
14. + channels of vascular smooth muscle. Circ Res 89:1030-1037, 2001
15. 2 receptor-mediated apoptosis and adhesion molecule expression in cultured human aortic endothelial cells. Diabetes 51:198-203, 2002
16. El Remessy AB, Abou-Mohamed G, Caldwell RW, Caldwell RB: High glucose-induced tyrosine nitration in endothelial cells: role of eNOS uncoupling and aldose reductase activation. Invest Ophthalmol Vis Sci 44:3135-3143, 2003
17. Zou MH, Shi C, Cohen RA: Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite. J Clin Invest 109:817-826, 2002
18. Halliwell B: What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo? FEBS Lett 411:157-160, 1997
19. Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B, van der Vliet A: Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 391:393-397, 1998
20. Radi R, Peluffo G, Alvarez MN, Naviliat M, Cayota A: Unraveling peroxynitrite formation in biological systems. Free Radic Biol Med 30:463-488, 2001
21. Liu Y, Gutterman DD: Oxidative stress and potassium channel function. Clin Exp Pharmacol Physiol 29:305-311, 2002