메뉴 건너뛰기




Volumn 190, Issue 5, 2004, Pages 886-893

Weighted phenotypic susceptibility scores are predictive of the HIV-1 RNA response in protease inhibitor-experienced HIV-1-infected subjects

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ADEFOVIR DIPIVOXIL; AMPRENAVIR; ANTIRETROVIRUS AGENT; DELAVIRDINE; DIDANOSINE; INDINAVIR; LAMIVUDINE; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; VIRUS RNA; ZALCITABINE; ZIDOVUDINE;

EID: 4344623482     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/422692     Document Type: Article
Times cited : (24)

References (44)
  • 1
    • 0030869269 scopus 로고    scopus 로고
    • Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy
    • Gulick RM, Mellors JW, Havlir D, et al. Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med 1997; 337:734-9.
    • (1997) N Engl J Med , vol.337 , pp. 734-739
    • Gulick, R.M.1    Mellors, J.W.2    Havlir, D.3
  • 2
    • 0442268112 scopus 로고    scopus 로고
    • A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less
    • Hammer SM, Squires KE, Hughes MD, et al. A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. N Engl J Med 1997; 337:725-33.
    • (1997) N Engl J Med , vol.337 , pp. 725-733
    • Hammer, S.M.1    Squires, K.E.2    Hughes, M.D.3
  • 3
    • 6844240219 scopus 로고    scopus 로고
    • Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease
    • Cameron DW, Heath-Chiozzi M, Danner S, et al. Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. Lancet 1998; 351:543-9.
    • (1998) Lancet , vol.351 , pp. 543-549
    • Cameron, D.W.1    Heath-Chiozzi, M.2    Danner, S.3
  • 4
    • 9844261693 scopus 로고    scopus 로고
    • Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centers
    • Mouton Y, Alfandari S, Valette M, et al. Impact of protease inhibitors on AIDS-defining events and hospitalizations in 10 French AIDS reference centers. AIDS 1997; 11:F101-5.
    • (1997) AIDS , vol.11
    • Mouton, Y.1    Alfandari, S.2    Valette, M.3
  • 5
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infections
    • Palella FJ Jr, Delaney KM, Moorman AC, et al. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infections. N Engl J Med 1998; 338:853-60.
    • (1998) N Engl J Med , vol.338 , pp. 853-860
    • Palella Jr., F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 6
    • 0033550965 scopus 로고    scopus 로고
    • Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: A prospective cohort study. Swiss HIV Cohort Study
    • Ledergerber B, Egger M, Opravil M, et al. Clinical progression and virological failure on highly active antiretroviral therapy in HIV-1 patients: a prospective cohort study. Swiss HIV Cohort Study. Lancet 1999; 353:863-8.
    • (1999) Lancet , vol.353 , pp. 863-868
    • Ledergerber, B.1    Egger, M.2    Opravil, M.3
  • 7
    • 0033587510 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy in a large urban clinic: Risk factors for virologic failure and adverse drug reactions
    • Lucas GM, Chaisson RE, Moore RD. Highly active antiretroviral therapy in a large urban clinic: risk factors for virologic failure and adverse drug reactions. Ann Intern Med 1999; 131:81-7.
    • (1999) Ann Intern Med , vol.131 , pp. 81-87
    • Lucas, G.M.1    Chaisson, R.E.2    Moore, R.D.3
  • 8
    • 0038234808 scopus 로고    scopus 로고
    • Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 Recommendations of an International AIDS Society-USA panel
    • Hirsch MS, Brun-Vezinet F, Clotet B, et al. Antiretroviral drug resistance testing in adults infected with human immunodeficiency virus type 1: 2003 recommendations of an International AIDS Society-USA panel. Clin Infect Dis 2003; 37:113-28.
    • (2003) Clin Infect Dis , vol.37 , pp. 113-128
    • Hirsch, M.S.1    Brun-Vezinet, F.2    Clotet, B.3
  • 9
    • 0033606540 scopus 로고    scopus 로고
    • Drug-resistance genotyping in HIV-1 therapy: The VIRADAPT randomised controlled trial
    • Durant J, Clevenbergh P, Halfon P, et al. Drug-resistance genotyping in HIV-1 therapy: the VIRADAPT randomised controlled trial. Lancet 1999; 353:2195-9.
    • (1999) Lancet , vol.353 , pp. 2195-2199
    • Durant, J.1    Clevenbergh, P.2    Halfon, P.3
  • 10
    • 0033920318 scopus 로고    scopus 로고
    • A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy
    • CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS
    • Baxter JD, Mayers DL, Wentworth DN, et al. A randomized study of antiretroviral management based on plasma genotypic antiretroviral resistance testing in patients failing therapy. CPCRA 046 Study Team for the Terry Beirn Community Programs for Clinical Research on AIDS. AIDS 2000; 14:F83-93.
    • (2000) AIDS , vol.14
    • Baxter, J.D.1    Mayers, D.L.2    Wentworth, D.N.3
  • 11
    • 0037169170 scopus 로고    scopus 로고
    • Clinical utility of HIV-1 genotyping and expert advice: The Havana trial
    • Tural C, Ruiz L, Holtzer C, et al. Clinical utility of HIV-1 genotyping and expert advice: the Havana trial. AIDS 2002; 16:209-18.
    • (2002) AIDS , vol.16 , pp. 209-218
    • Tural, C.1    Ruiz, L.2    Holtzer, C.3
  • 12
    • 0037040360 scopus 로고    scopus 로고
    • A randomized trial assessing the impact of phenotypic resistance testing on antiretroviral therapy
    • Cohen CJ, Hunt S, Sension M, et al. A randomized trial assessing the impact of phenotypic resistance testing on antiretroviral therapy. AIDS 2002; 16:579-88.
    • (2002) AIDS , vol.16 , pp. 579-588
    • Cohen, C.J.1    Hunt, S.2    Sension, M.3
  • 13
    • 0037192551 scopus 로고    scopus 로고
    • Phenotypic or genotypic resistance testing for choosing antiretroviral therapy after treatment failure: A randomized trial
    • Meynard JL, Vray M, Morand-Joubert L, et al. Phenotypic or genotypic resistance testing for choosing antiretroviral therapy after treatment failure: a randomized trial. AIDS 2002; 16:727-36.
    • (2002) AIDS , vol.16 , pp. 727-736
    • Meynard, J.L.1    Vray, M.2    Morand-Joubert, L.3
  • 14
    • 0032990266 scopus 로고    scopus 로고
    • Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: Antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome
    • Deeks SG, Hellmann NS, Grant RM, et al. Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome. J Infect Dis 1999; 179:1375-81.
    • (1999) J Infect Dis , vol.179 , pp. 1375-1381
    • Deeks, S.G.1    Hellmann, N.S.2    Grant, R.M.3
  • 15
    • 0032750440 scopus 로고    scopus 로고
    • Baseline HIV drug resistance profile predicts response to ritonavir-saquinavir protease inhibitor therapy in a community setting
    • Harrigan PR, Hertogs K, Verbiest W, et al. Baseline HIV drug resistance profile predicts response to ritonavir-saquinavir protease inhibitor therapy in a community setting. AIDS 1999; 13:1863-71.
    • (1999) AIDS , vol.13 , pp. 1863-1871
    • Harrigan, P.R.1    Hertogs, K.2    Verbiest, W.3
  • 16
    • 0033009094 scopus 로고    scopus 로고
    • Impact of drug resistance mutations on virologic response to salvage therapy. Swiss HIV Cohort Study
    • Lorenzi P, Opravil M, Hirschel B, et al. Impact of drug resistance mutations on virologic response to salvage therapy. Swiss HIV Cohort Study. AIDS 1999; 13:F17-21.
    • (1999) AIDS , vol.13
    • Lorenzi, P.1    Opravil, M.2    Hirschel, B.3
  • 17
    • 0032839921 scopus 로고    scopus 로고
    • Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: Phenotypic resistance to protease inhibitors predicts outcome of therapy
    • Piketty C, Race E, Castiel P, et al. Efficacy of a five-drug combination including ritonavir, saquinavir and efavirenz in patients who failed on a conventional triple-drug regimen: phenotypic resistance to protease inhibitors predicts outcome of therapy. AIDS 1999; 13:F71-7.
    • (1999) AIDS , vol.13
    • Piketty, C.1    Race, E.2    Castiel, P.3
  • 18
    • 0033534115 scopus 로고    scopus 로고
    • HIV-1 genotypic resistance patterns predict response to saquinavir-ritonavir therapy in patients in whom previous protease inhibitor therapy had failed
    • Zolopa AR, Shafer RW, Warford A, et al. HIV-1 genotypic resistance patterns predict response to saquinavir-ritonavir therapy in patients in whom previous protease inhibitor therapy had failed. Ann Intern Med 1999; 131:813-21.
    • (1999) Ann Intern Med , vol.131 , pp. 813-821
    • Zolopa, A.R.1    Shafer, R.W.2    Warford, A.3
  • 19
    • 0344593433 scopus 로고    scopus 로고
    • The relation between baseline HIV drug resistance and response to antiretroviral therapy: Re-analysis of retrospective and prospective studies using a standardized data analysis plan
    • DeGruttola V, Dix L, D'Aquila R, et al. The relation between baseline HIV drug resistance and response to antiretroviral therapy: re-analysis of retrospective and prospective studies using a standardized data analysis plan. Antivir Ther 2000; 5:41-8.
    • (2000) Antivir Ther , vol.5 , pp. 41-48
    • Degruttola, V.1    Dix, L.2    D'Aquila, R.3
  • 20
    • 17544379494 scopus 로고    scopus 로고
    • HIV drug susceptibility and treatment response to mega-HAART regimen in patients from the Frankfurt HIV cohort
    • Miller V, Cozzi-Lepri A, Hertogs K, et al. HIV drug susceptibility and treatment response to mega-HAART regimen in patients from the Frankfurt HIV cohort. Antivir Ther 2000; 5:49-55.
    • (2000) Antivir Ther , vol.5 , pp. 49-55
    • Miller, V.1    Cozzi-Lepri, A.2    Hertogs, K.3
  • 21
    • 0033930825 scopus 로고    scopus 로고
    • Phenotypic testing predicts virological response in successive protease inhibitor-based regimens
    • Perez-Elias MJ, Lanier R, Munoz V, et al. Phenotypic testing predicts virological response in successive protease inhibitor-based regimens. AIDS 2000; 14:F95-101.
    • (2000) AIDS , vol.14
    • Perez-Elias, M.J.1    Lanier, R.2    Munoz, V.3
  • 22
    • 0033831385 scopus 로고    scopus 로고
    • Simple algorithm derived from a geno-/phenotypic database to predict HIV-1 protease inhibitor resistance
    • Schmidt B, Walter H, Moschik B, et al. Simple algorithm derived from a geno-/phenotypic database to predict HIV-1 protease inhibitor resistance. AIDS 2000; 14:1731-8.
    • (2000) AIDS , vol.14 , pp. 1731-1738
    • Schmidt, B.1    Walter, H.2    Moschik, B.3
  • 23
    • 0033914844 scopus 로고    scopus 로고
    • Methods for investigation of the relationship between drug-susceptibility phenotype and human immunodeficiency virus type 1 genotype with applications to AIDS Clinical Trials Group 333
    • Sevin AD, DeGruttola V, Nijhuis M, et al. Methods for investigation of the relationship between drug-susceptibility phenotype and human immunodeficiency virus type 1 genotype with applications to AIDS Clinical Trials Group 333. J Infect Dis 2000; 182:59-67.
    • (2000) J Infect Dis , vol.182 , pp. 59-67
    • Sevin, A.D.1    DeGruttola, V.2    Nijhuis, M.3
  • 24
    • 0035253297 scopus 로고    scopus 로고
    • Phenotypic drug susceptibility testing predicts long-term virologic suppression better than treatment history in patients with human immunodeficiency virus infection
    • Call SA, Saag MS, Westfall AO, et al. Phenotypic drug susceptibility testing predicts long-term virologic suppression better than treatment history in patients with human immunodeficiency virus infection. J Infect Dis 2001; 183:401-8.
    • (2001) J Infect Dis , vol.183 , pp. 401-408
    • Call, S.A.1    Saag, M.S.2    Westfall, A.O.3
  • 25
    • 0035835499 scopus 로고    scopus 로고
    • Phenotypic cross-resistance to nelfinavir: The role of prior antiretroviral therapy and the number of mutations in the protease gene
    • Dronda F, Casado JL, Moreno S, et al. Phenotypic cross-resistance to nelfinavir: the role of prior antiretroviral therapy and the number of mutations in the protease gene. AIDS Res Hum Retroviruses 2001; 17: 211-5.
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 211-215
    • Dronda, F.1    Casado, J.L.2    Moreno, S.3
  • 26
    • 0034755057 scopus 로고    scopus 로고
    • Impact of HIV type 1 drug resistance mutations and phenotypic resistance profile on virologic response to salvage therapy
    • Ross L, Liao Q, Gao H, et al. Impact of HIV type 1 drug resistance mutations and phenotypic resistance profile on virologic response to salvage therapy. AIDS Res Hum Retroviruses 2001; 17:1379-85.
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 1379-1385
    • Ross, L.1    Liao, Q.2    Gao, H.3
  • 27
    • 0037016433 scopus 로고    scopus 로고
    • Plasma drug levels, genotypic resistance, and virological response to a nelfinavir plus saquinavir-containing regimen
    • Casado JL, Moreno S, Hertogs K, et al. Plasma drug levels, genotypic resistance, and virological response to a nelfinavir plus saquinavir-containing regimen. AIDS 2002; 16:47-52.
    • (2002) AIDS , vol.16 , pp. 47-52
    • Casado, J.L.1    Moreno, S.2    Hertogs, K.3
  • 28
    • 0037083807 scopus 로고    scopus 로고
    • HIV-1 genotype and phenotype correlate with virological response to abacavir, amprenavir and efavirenz in treatment-experienced patients
    • Falloon J, Ait-Khaled M, Thomas DA, et al. HIV-1 genotype and phenotype correlate with virological response to abacavir, amprenavir and efavirenz in treatment-experienced patients. AIDS 2002; 16:387-96.
    • (2002) AIDS , vol.16 , pp. 387-396
    • Falloon, J.1    Ait-Khaled, M.2    Thomas, D.A.3
  • 29
    • 0037626084 scopus 로고    scopus 로고
    • Phenotypic susceptibility and virological outcome in nucleoside- experienced patients receiving three or four antiretroviral drugs
    • Katzenstein DA, Bosch RJ, Hellmann N, Wang N, Bacheler L, Albrecht MA. Phenotypic susceptibility and virological outcome in nucleoside-experienced patients receiving three or four antiretroviral drugs. AIDS 2003; 17:821-30.
    • (2003) AIDS , vol.17 , pp. 821-830
    • Katzenstein, D.A.1    Bosch, R.J.2    Hellmann, N.3    Wang, N.4    Bacheler, L.5    Albrecht, M.A.6
  • 30
    • 0033794231 scopus 로고    scopus 로고
    • Randomized study of saquinavir with ritonavir or nelfinavir together with delavirdine, adefovir, or both in human immunodeficiency virus-infected adults with virologic failure on indinavir. AIDS Clinical Trials Group Study 359
    • Gulick RM, Hu XJ, Fiscus SA, et al. Randomized study of saquinavir with ritonavir or nelfinavir together with delavirdine, adefovir, or both in human immunodeficiency virus-infected adults with virologic failure on indinavir. AIDS Clinical Trials Group Study 359. J Infect Dis 2000; 182:1375-84.
    • (2000) J Infect Dis , vol.182 , pp. 1375-1384
    • Gulick, R.M.1    Hu, X.J.2    Fiscus, S.A.3
  • 31
    • 0036720473 scopus 로고    scopus 로고
    • Durability of response to treatment among antiretroviral-experienced subjects: 48-Week results from AIDS Clinical Trials Group Protocol 359
    • Gulick RM, Hu XJ, Fiscus SA, et al. Durability of response to treatment among antiretroviral-experienced subjects: 48-week results from AIDS Clinical Trials Group Protocol 359. J Infect Dis 2002; 186:626-33.
    • (2002) J Infect Dis , vol.186 , pp. 626-633
    • Gulick, R.M.1    Hu, X.J.2    Fiscus, S.A.3
  • 32
    • 0034019566 scopus 로고    scopus 로고
    • A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1
    • Petropoulos CJ, Parkin NT, Limoli KL, et al. A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1. Antimicrob Agents Chemother 2000; 44:920-8.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 920-928
    • Petropoulos, C.J.1    Parkin, N.T.2    Limoli, K.L.3
  • 33
    • 0034672295 scopus 로고    scopus 로고
    • Analysis and design issues for studies using censored biomarker measurements with an example of viral load measurements in HIV clinical trials
    • Hughes MD. Analysis and design issues for studies using censored biomarker measurements with an example of viral load measurements in HIV clinical trials. Stat Med 2000; 19:3171-91.
    • (2000) Stat Med , vol.19 , pp. 3171-3191
    • Hughes, M.D.1
  • 34
    • 84908219488 scopus 로고
    • Statistical methods for assessing agreement between two methods of clinical measurement
    • Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 1:307-10.
    • (1986) Lancet , vol.1 , pp. 307-310
    • Bland, J.M.1    Altman, D.G.2
  • 36
  • 37
    • 0034639490 scopus 로고    scopus 로고
    • Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens
    • Havlir DV, Hellmann NS, Petropoulos CJ, et al. Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens. JAMA 2000; 283:229-34.
    • (2000) JAMA , vol.283 , pp. 229-234
    • Havlir, D.V.1    Hellmann, N.S.2    Petropoulos, C.J.3
  • 38
    • 0032750954 scopus 로고    scopus 로고
    • Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies
    • Race E, Dam E, Obry V, Paulous S, Clavel F. Analysis of HIV cross-resistance to protease inhibitors using a rapid single-cycle recombinant virus assay for patients failing on combination therapies. AIDS 1999; 13:2061-8.
    • (1999) AIDS , vol.13 , pp. 2061-2068
    • Race, E.1    Dam, E.2    Obry, V.3    Paulous, S.4    Clavel, F.5
  • 39
    • 0033921617 scopus 로고    scopus 로고
    • Phenotypic and genotypic analysis of clinical HIV-1 isolates reveals extensive protease inhibitor cross-resistance: A survey of over 6000 samples
    • Hertogs K, Bloor S, Kemp SD, et al. Phenotypic and genotypic analysis of clinical HIV-1 isolates reveals extensive protease inhibitor cross-resistance: a survey of over 6000 samples. AIDS 2000; 14:1203-10.
    • (2000) AIDS , vol.14 , pp. 1203-1210
    • Hertogs, K.1    Bloor, S.2    Kemp, S.D.3
  • 40
    • 15144357022 scopus 로고    scopus 로고
    • The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir
    • Kempf DJ, Rode RA, Xu Y, et al. The duration of viral suppression during protease inhibitor therapy for HIV-1 infection is predicted by plasma HIV-1 RNA at the nadir. AIDS 1998; 12:F9-14.
    • (1998) AIDS , vol.12
    • Kempf, D.J.1    Rode, R.A.2    Xu, Y.3
  • 41
    • 0036138037 scopus 로고    scopus 로고
    • Development and significance of resistance to protease inhibitors in HIV-1-infected adults under triple-drug therapy in clinical practice
    • Romano L, Venturi G, Giomi S, Pippi L, Valensin PE, Zazzi M. Development and significance of resistance to protease inhibitors in HIV-1-infected adults under triple-drug therapy in clinical practice. J Med Virol 2002; 66:143-50.
    • (2002) J Med Virol , vol.66 , pp. 143-150
    • Romano, L.1    Venturi, G.2    Giomi, S.3    Pippi, L.4    Valensin, P.E.5    Zazzi, M.6
  • 42
    • 7344250684 scopus 로고    scopus 로고
    • Suppression of plasma viral load below 20 copies/mL is required to achieve a long-term response to therapy
    • Raboud JM, Montaner JS, Conway B, et al. Suppression of plasma viral load below 20 copies/mL is required to achieve a long-term response to therapy. AIDS 1998; 12:1619-24.
    • (1998) AIDS , vol.12 , pp. 1619-1624
    • Raboud, J.M.1    Montaner, J.S.2    Conway, B.3
  • 43
    • 0033520673 scopus 로고    scopus 로고
    • Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy
    • Dornadula G, Zhang H, VanUitert B, et al. Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy. JAMA 1999; 282:1627-32.
    • (1999) JAMA , vol.282 , pp. 1627-1632
    • Dornadula, G.1    Zhang, H.2    Vanuitert, B.3
  • 44
    • 0033609374 scopus 로고    scopus 로고
    • Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy
    • Furtado MR, Callaway DS, Phair JP, et al. Persistence of HIV-1 transcription in peripheral-blood mononuclear cells in patients receiving potent antiretroviral therapy. N Engl J Med 1999; 340:1614-22.
    • (1999) N Engl J Med , vol.340 , pp. 1614-1622
    • Furtado, M.R.1    Callaway, D.S.2    Phair, J.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.