An efficient and selective tosylation of alcohols with p-toluenesulfonic acid

Tetrahedron Letters

Volumn 45, Issue 36, 2004, Pages 6717-6719

  Das, Biswanath ^a   Reddy, V Saidi ^a   Reddy, M Ravinder ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Alcohols; p TsOH; Selectivity; Silica chloride; Tosylation

Indexed keywords

ALCOHOL DERIVATIVE; DICHLOROMETHANE; SILICA CHLORIDE; SILICON DIOXIDE; SULFONIC ACID DERIVATIVE; TOLUENESULFONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CATALYST; CHEMICAL REACTION; STEREOCHEMISTRY; TOSYLATION;

EID: 4344617214     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.07.076     Document Type: Article

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17. 2 (10 mL). Silica chloride (100 mg) was added and the mixture was heated under reflux. The reaction was monitored by TLC. After completion, the reaction mixture was filtered and the concentrated filtrate was subjected to column chromatography over silica gel using EtOAc-hexane (1:4) as eluent to obtain analytically pure tosylate