Synergistic interaction of two independent genetic loci causes extreme elevation of serum IgA in mice

Genes and Immunity

Volumn 5, Issue 5, 2004, Pages 375-380

  Schneider, B ^a   Hanke, P ^a   Jagla, W ^a   Wattler, S ^a   Nehls, M ^a   Grosse, J ^a   Schroder A ^a,b   Laufs, Juergen ^a  

^a Ingenium Pharmaceuticals AG   (Germany)

^b Baxter Bioscience   (Germany)

Author keywords

Chromosomal mapping; ENU mutagenesis; Ig germline switch; Immunoglubulin A (IgA); J chain (IgJ); Quantitative trait locus (QTL)

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; CHROMOSOMAL LOCALIZATION; CHROMOSOME 12; CHROMOSOME 5; CHROMOSOME MAP; CONTROLLED STUDY; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; GENOTYPE; IMMUNOGLOBULIN BLOOD LEVEL; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; QUANTITATIVE TRAIT LOCUS; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; UPREGULATION;

AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES; DNA MUTATIONAL ANALYSIS; ETHYLNITROSOUREA; IMMUNOGLOBULIN A; IMMUNOGLOBULIN J-CHAINS; MALE; MICE; MICE, INBRED C3H; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POINT MUTATION; QUANTITATIVE TRAIT LOCI; UP-REGULATION;

MURINAE;

EID: 4344610681     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6364105     Document Type: Article

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