Effect of exogenous p73 gene on chemosensitivity of wild-type p53 human lung adenocarcinoma cell A549

Chinese Journal of Lung Cancer

Volumn 7, Issue 4, 2004, Pages 331-335

  He, Yong ^a   Fan, Shizhi ^a   Jiang, Yaoguang ^a   Chen, Jianming ^a   Li, Zhiping ^a   Zhou, Ping ^a   Zhou, Yuanguo ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Chemosensitivity; Gene transfection; Lung neoplasms; p73 gene

Indexed keywords

CISPLATIN; COMPLEMENTARY DNA; DNA FRAGMENT; DOXORUBICIN; LIPOFECTAMINE; PROTEIN P53; PROTEIN P73;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CHEMOSENSITIVITY; COLONY FORMATION; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; PROTEIN EXPRESSION;

EID: 4344606139     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Weller M. Predicting response to cancer chemotherapy: the role of p53. Cell Tissue Res, 1998, 292(3): 435-445.
2. Dorigo O, Turla ST, Lebedeva S, et al. Sensitization of rat glioblastoma multiforme to cisplatin in vivo following restoration of wild-type p53 function. J Neurosurg, 1998, 88(3): 535-540.
3. Inoue A, Narumi K, Matsubara N, et al. Administration of wild-type p53 adenoviral vector synergistically enhances the cytotoxicity of anti-cancer drugs in human lung cancer cells irrespective of the status of p53 gene. Cancer Lett, 2000, 157(1): 105-112.
4. Nemunaitis J, Swisher SG, Timmons T, et al. Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. J Clin Oncol, 2000, 18(3): 609-622.
5. Horio Y, Hasegawa Y, Sekido Y, et al. Synergistic effects of adenovirus expressing wild type p53 on chemosensitivity of non-small cell lung cancer cells. Cancer Gene Ther, 2000, 7(4): 537-544.
6. Kagawa S, Gu J, Swisher SG, et al. Antitumor effect of adenovirus-mediated Bax gene transfer on p53-sensitive and p53-resistant cancer lines. Cancer Res, 2000, 60(5): 1157-1161.
7. Agami R, Bernards R. Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage. Cell, 2000, 102(1): 55-66.