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Journal of Pharmaceutical and Biomedical Analysis

Volumn 35, Issue 5, 2004, Pages 1113-1125

Degradation of camptothecin-20(S)-glycinate ester prodrug under physiological conditions

(5) Liu, Xinli a Zhang, Junhong a Song, Lin a Lynn, Bert C a Burke, Thomas G a

a UNIVERSITY OF KENTUCKY (United States)

Author keywords

camptothecin; camptothecin 20(S) acetate; camptothecin 20(S) glycinate; CPT; CPT 20(S) acetate; CPT 20(S) glycinate; LC ESI MS; liquid chromatography electrospray ionization mass spectrometry; PBS; phosphate buffered saline; RP HPLC

Indexed keywords

AMINO ACID; BUFFER; CAMPTOTHECIN; ESTER DERIVATIVE; PHOSPHATE; SODIUM CHLORIDE;

ARTICLE; CORRELATION ANALYSIS; DECOMPOSITION; DEGRADATION; DRUG DEGRADATION; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FRAGMENTATION REACTION; HUMAN; HYDROLYSIS; INFORMATION; PLASMA; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; GLYCINE; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MOLECULAR STRUCTURE; PRODRUGS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TIME FACTORS;

EID: 4344600433 PISSN: 07317085 EISSN: None Source Type: Journal
DOI: 10.1016/j.jpba.2004.04.006 Document Type: Article

Times cited : (13)

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