Detection of circulating superantigens in an intensive care unit population

International Journal of Infectious Diseases

Volumn 8, Issue 5, 2004, Pages 292-298

  Azuma, Kazuaki ^a   Koike, Kaoru ^b   Kobayashi, Tatsuho ^a   Mochizuki, Toru ^a   Mashiko, Kunihiro ^a   Yamamoto, Yasuhiro ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Enzyme linked immunosorbent assay; Gram positive bacteria; Intensive care unit; Sepsis; Septic shock; Superantigens

Indexed keywords

BACTERIAL ANTIGEN; EXOTOXIN; PYROGENIC EXOTOXIN A; STAPHYLOCOCCUS ENTEROTOXIN; STAPHYLOCOCCUS ENTEROTOXIN A; STAPHYLOCOCCUS ENTEROTOXIN B; STAPHYLOCOCCUS ENTEROTOXIN C; SUPERANTIGEN; TOXIC SHOCK SYNDROME TOXIN 1; UNCLASSIFIED DRUG;

ABDOMINAL DISEASE; ADULT; AGED; ANTIGEN DETECTION; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; BURN; CARDIOVASCULAR DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; INJURY; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; RESPIRATORY TRACT DISEASE; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TOXIC SHOCK SYNDROME;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL PROTEINS; BACTERIAL TOXINS; ENTEROTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EXOTOXINS; FEMALE; HUMANS; INTENSIVE CARE UNITS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; SEPSIS; SHOCK, SEPTIC; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS;

EID: 4344568775     PISSN: 12019712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijid.2003.12.005     Document Type: Article

References (25)

1. Brun-Buisson C., Doyon F., Carlet J., et al. Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. JAMA. 274:1995;968-974
2. Bochud P.Y., Calandra T., Francioli P. Bacteremia due to viridans streptococci in neutropenic patients: a review. Am J Med. 97:1994;256-264
3. Rangel-Frausto M.S. The epidemiology of bacterial sepsis. Infect Dis Clin North Am. 13:1999;299-312
4. Sriskandan S., Cohen J. Gram-positive sepsis. Mechanisms and differences from Gram-negative sepsis. Infect Dis Clin North Am. 13:1999;397-412
5. Opal S.M., Cohen J. Clinical Gram-positive sepsis: does it fundamentally differ from Gram-negative bacterial sepsis? Crit Care Med. 27:1999;1608-1616
6. Silverstein R., Norimatsu M., Morrison D.C. Fundamental differences during Gram-positive versus Gram-negative sepsis become apparent during bacterial challenge of D-galactosamine-treated mice. J Endotoxin Res. 4:1997;173-181
7. Becker K., Friedrich A.W., Lubritz G., Weilert M., Peters G., Eiff C. Prevalence of genes encoding pyrogenic toxin superantigens and exfoliative toxins among strains of Staphylococcus aureus isolated from blood and nasal specimens. J Clin Microbiol. 41:2003;1434-1439
8. Proft T., Moffatt S.L., Berkahn C.J., Fraser J.D. Identification and characterization of novel superantigens from Streptococcus pyogenes. J Exp Med. 189:1999;89-102
9. Proft T., Webb P.D., Handley V., Fraser J.D. Two novel superantigens found in both group A and group C Streptococcus. Infect Immun. 71:2003;1361-1369
10. Bergdoll MS. The staphylococcal enterotoxins - an update. In: Jeljaszewicz J, editor. The Staphylococci. New York: Gustav Fischer Verlag; 1985.
11. Stevens D.L., Tanner M.H., Winship J., et al. Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A. New Engl J Med. 321:1989;1-7
12. Bohach G.A., Fast D.J., Nelson R.D., Schlievert P.M. Staphylococcal and streptococcal pyrogenic toxins involved in toxic shock syndrome and related illnesses. Crit Rev Microbiol. 17:1990;251-272
13. Uchiyama T., Yan X.J., Imanishi K., Yagi J. Bacterial superantigens - mechanism of T cell activation by the superantigens and their role in the pathogenesis of infectious diseases. Microbiol Immunol. 38:1994;245-256
14. Jupin C., Anderson S., Damais C., Alouf J.E., Parant M. Toxic shock syndrome toxin 1 as an inducer of human tumor necrosis factors and gamma interferon. J Exp Med. 167:1988;752-761
15. Krakauer T. Interleukin-8 production by human monocytic cells in response to staphylococcal exotoxins is direct and independent of interleukin-1 and tumor necrosis factor-alpha. J Infect Dis. 178:1998;573-577
16. Igarashi H., Fujikawa H., Usami H. Effects of drugs on the pyrogenicity of toxic shock syndrome toxin 1 and its capacity to enhance susceptibility to the lethal effects of endotoxic shock in rabbits. Rev Infect Dis. 11:1989;S210-S213
17. Wells D.E., Reeves M.W., McKinney R.M., et al. Production and characterization of monoclonal antibodies to toxic shock syndrome toxin1 and use of a monoclonal antibody in rapid, one-step enzyme-linked immunosorbent assays for the detection of picogram quantities of toxic shock syndrome toxin 1. J Clin Microbiol. 25:1987;519-521
18. Miwa K., Fukuyama M., Kunitomo T., Igarashi H. Rapid assay for detection of toxic shock syndrome toxin 1 from human sera. J Clin Microbiol. 32:1994;539-542
19. Sriskandan S., Moyer D., Cohen J. Detection of circulating bacterial superantigen and lymphotoxin-α in patients with streptococcal toxic-shock syndrome. Lancet. 348:1996;1315-1316
20. Anonymous. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992;20:864-74.
21. Miwa K., Fukuyama M., Sakai R., et al. Sensitive enzyme-linked immunosorbent assays for detection of bacterial superantigens and antibodies against them in human plasma. Microbiol Immunol. 44:2000;519-523
22. Ryan T.A. Significance tests for multiple comparison of proportions, variances, and other statistics. Psychol Bull. 57:1960;318-328
23. Blomster-Hautamaa D.A., Kreiswirth B.N., Kornblum J.S., Novick R.P., Schlievert P.M. The nucleotide and partial amino acid sequence of toxic shock syndrome toxin-1. J Biol Chem. 261:1986;15783-15786
24. Acharya K.R., Passalacqua E.F., Jones E.Y., et al. Structural basis of superantigen action inferred from crystal structure of toxic-shock syndrome toxin-1. Nature. 367:1994;94-97
25. Hensler T., Koller M., Geoffroy C., Alouf J.E., Konig W. Staphylococcus aureus toxic shock syndrome toxin 1 and Streptococcus pyogenes erythrogenic toxin A modulate inflammatory mediator release from human neutrophils. Infect Immun. 61:1993;1055-1061