Investigation of the effect of acepromazine on intravenous glucose tolerance tests in dogs

American Journal of Veterinary Research

Volumn 65, Issue 8, 2004, Pages 1124-1127

  Ionut, Viorica ^a   Kirkman, Erlinda L ^a   Bergman, Richard N ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACEPROMAZINE MALEATE; FATTY ACID; GLUCOSE; INSULIN; LACTIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DATA ANALYSIS; DIET RESTRICTION; DOG; DOSE RESPONSE; DRUG EFFECT; FATTY ACID BLOOD LEVEL; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN BLOOD LEVEL; INSULIN RESPONSE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; KINETICS; LACTATE BLOOD LEVEL; MALE; NONHUMAN; RANDOMIZATION;

ACEPROMAZINE; ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; DOGS; FATTY ACIDS, NONESTERIFIED; GLUCOSE TOLERANCE TEST; INSULIN; LACTIC ACID; MODELS, BIOLOGICAL; TIME FACTORS; TRANQUILIZING AGENTS;

ANIMALIA; CANIS FAMILIARIS;

EID: 4344564966     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2004.65.1124     Document Type: Article

References (25)

1. Paddleford RR. Preanesthetic agents. In: Paddleford RR, ed. Manual of small animal anesthesia. Philadelphia: WB Saunders Co, 1999; 12-17.
2. Lemke K. Preanesthetics and anesthetic adjuncts. In: Thurmon JC, Tranquilli WJ, Benson GJ, eds. Essentials of small animal anesthesia and analgesia. Philadelphia: Lippincott Williams & Wilkins, 1999; 128-129.
3. Lumb WJ. Preanesthetic agents. In: Lumb WV, Jones EW, eds. Veterinary anesthesia. Philadelphia: Lea & Febiger, 1973;184-187.
4. Bergman RN, Bowden CR. The minimal model approach to quantification of factors controlling glucose disposal in man. In: Cobelli C, Bergman RN, eds. Carbohydrate metabolism: quantitative physiology and mathematical modeling. New York: John Wiley & Sons, 1981;269-296.
5. Pacini G, Bergman RN. MINMOD: a computer program to calculate insulin sensitivity and pancreatic responsivity from the frequently sampled intravenous glucose tolerance test. Comput Methods Programs Biomed 1986;23:113-122.
6. Bergman RN, Ader M, Huecking K, et al. Accurate assessment of beta-cell function: the hyperbolic correction. Diabetes 2002;51(suppl 1):S212-S220.
7. Bergman RN, Watanabe R, Rebrin K, et al. Toward an integrated phenotype in pre-NIDDM. Diabet Med 1996;13(9 suppl 6):S67-S77.
8. Mittelman SD, Van Citters GW, Kim SP, et al. Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response. Diabetes 2000;49:2116-2125.
9. Chen M, Bergman RN, Porte D Jr. Insulin resistance and beta-cell dysfunction in aging: the importance of dietary carbohydrate. J Clin Endocrinol Metab 1988;67:951-957.
10. Steil GM, Ader M, Moore DM, et al. Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process. J Clin Invest 1996;97:1497-1503.
11. Toso CF, Rodriguez RR, Renauld A, et al. Blood sugar, serum insulin and serum non-esterified fatty acid levels during thiopentone anaesthesia in dogs. Can J Anaesth 1993;40:38-45.
12. Aynsley-Green A, Biebuyck JF, Alberti KG. Anaesthesia and insulin secretion: the effects of diethyl ether, halothane, pentobarbitone sodium and ketamine hydrochloride on intravenous glucose tolerance and insulin secretion in the rat. Diabetologia 1973;9:274-281.
13. Vera ER, Battell ML, Bhanot S, et al. Effects of age and anesthetic on plasma glucose and insulin levels and insulin sensitivity in spontaneously hypertensive and Wistar rats. Can J Physiol Pharmacol 2002;80:962-970.
14. Amar D, Shamoon H, Lazar EJ, et al. Acute hyperglycaemic effect of anaesthetic induction with thiopentone. Acta Anaesthesiol Scand 1993;37:571-574.
15. Najim RA, al-Essa LY, al-Jawad FH. Effect of some drugs acting at the central-type benzodiazepine receptors on blood glucose in mice. Clin Exp Pharmacol Physiol 1989;16:7-12.
16. Ambrisko TD, Hikasa Y. Neurohormonal and metabolic effects of medetomidine compared with xylazine in beagle dogs. Can J Vet Res 2002;66:42-49.
17. Dwyer DS, Donohoe D. induction of hyperglycemia in mice with atypical antipsychotic drugs that inhibit glucose uptake. Pharmacol Biochem Behav 2003;75:255-260.
18. Sato S, Katayama K, Kakemi M, et al. A kinetic study of chlorpromazine on the hyperglycemic response in rats. II. Effect of chlorpromazine on plasma glucose. J Pharmacobiodyn 1988;11:492-503.
19. Erle G, Basso M, Federspil G, et al. Effect of chlorpromazine on blood glucose and plasma insulin in man. Eur J Clin Pharmacol 1977; 11:15-18.
20. Hsu WH, Hembrough FB. Intravenous glucose tolerance test in cats: influenced by acetylpromazine, ketamine, morphine, thiopental, and xylazine. Am J Vet Res 1982;43:2060-2061.
21. Beard JC, Bergman RN, Ward WK, et al. The insulin sensitivity index in nondiabetic man. Correlation between clamp-derived and IVGTT-derived values. Diabetes 1986;35:362-369.
22. Bugajski J, Lech J. Effects of neuroleptics on blood glucose, free fatty acids and liver glycogen levels in the rat. Pol J Pharmacol Pharm 1979;31:45-58.
23. Frisk-Holmberg M, Lluch S, Rosell S. Chlorpromazine-induced histamine release and lipolysis in canine adipose tissue in situ. Eur J Pharmacol 1971;15:350-354.
24. Bradley PB. Neuroleptic drugs. In: Bradley PB, ed. Introduction to neuropharmacology. Boston: Wright, 1989;204-207.
25. Arias HR. Binding sites for exogenous and endogenous non-competitive inhibitors of the nicotinic acetylcholine receptor. Biochim Biophys Acta 1998;1376:173-220.