Impact and mechanism of TiO2 nanoparticles on DNA synthesis in vitro

Science in China, Series B: Chemistry

Volumn 51, Issue 4, 2008, Pages 367-372

  Li, ShiQiang ^a   Zhu, Hong ^a   Zhu, RongRong ^a   Sun, XiaoYu ^a   Yao, SiDe ^a   Wang, ShiLong ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

DNA synthesis; Molecular mechanism; PCR; TiO2 nanoparticles

Indexed keywords

BIOSYNTHESIS; DNA; MOLECULAR ELECTRONICS; PRECIPITATION (CHEMICAL); TITANIUM DIOXIDE; ULTRAVIOLET SPECTROSCOPY;

DNA SYNTHESIS; MOLECULAR MECHANISM; POLYMERASE CHAIN REACTION (PCR) SYSTEM;

NANOPARTICLES;

EID: 43349098455     PISSN: 10069291     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11426-008-0049-9     Document Type: Article

References (19)

1. Medina C, Santos-Martinez M J, Radomski A, Corrigan O I, Radomskil M W. Nanoparticles: Pharmacological and toxicological significance. Br J Pharmacol, 2007, 150(5): 552-558
2. Howard M K, Debra L L. Smaller is not always better: nanotechnology yields Nanotoxicology. AJP: Lung, 2005, 289(5): 696-697
3. Kagan V, Bayir H, Shvedova A A. Nanomedicine and nanotoxicology: Two sides of the same coin. Nanomedicine, 2005, 1: 313-316
4. 2 nanoparticles. J Toxicology (in Chinese), 2006, 20(5): 334-336
5. Wang B, Feng W Y, Zhao Y L, Xing G M, CHAI Z F, Wang H F, Jia G. Research of materials' biological action and its toxicology development. Sci China Ser B-Chem (in Chinese), 2005, 35(1): 1-10
6. 2 particles: Differential responses related to surface properties. Toxicology, 2007, 230(1): 90-104
7. Wang J X, Zhou G Q, Chen C Y, Yu H W, Wang T C, Ma Y M, Jia G, Gao Y X, Li B, Sun J, Li Y F, Jiao F, Zhao Y L, Chai Z F. Acute toxicity and biodistribution of different sized titanium dioxide particles in mice after oral administration. Toxicology Lett, 2007, 168: 176-185
8. Bermudez E, Mangum J B, Wong B A, Asgharian B, Hext P M, Warheit D B, Everitt J I. Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci, 2004, 77(2): 347-357
9. Jani P U, McCarthy D E, Florence A T, Titanium dioxide (rutile) particles uptake from the rat GI tract and translocation to systemic organs after oral administration. Int J Pharm, 1994, 105: 157-168
10. Rothen-Rutishauser B M, Schürch S, Haenni B, Kapp N, Gehr P. Interaction of fine particles and nanoparticles with red blood cells visualized with advanced microscopic techniques. Environ Sci Technol, 2006, 40(14): 4353-4359
11. Thomas C L, Navid S, Robert D T. Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): Implications for nanoparticle neurotoxicity. Environ Sci Technol, 2006, 40(14): 4346-4352
12. Renwick L C, Brown D, Clouter A, Donaldson K. Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types. Occup Environ Med, 2004, 61: 442-447
13. 2 rods and dots in rats: toxicity is not dependent upon particle size and surface area. Toxicol Sci, 2006, 91: 227-236
14. Sambrook J, Russell D. Molecular Cloning (in Chinese). 3rd ed. Beijing: Science Press, 2002. 419-425
15. Zhang Z X, Zhao H W, Zhu H P, Ge M, Wang W F, Yao S D, Li W X. Research of the photoallergy damage of lactochrome on lysozyme detected by SDS-PGE. Sci China Ser B-Chem (in Chinese), 2001, 31(6): 550-556
16. Mullis K B, Faloona F A. Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol, 1987, 155: 335-350
17. 2 nanoparticles on DNA structure. Chin J Chem, 2007, 25(7): 958-961
18. 2. Sci China Ser B-Chem, 2007, 50(2): 272-275
19. Cedervall T, Lynch I, Lindman S L. Understanding the nanoparticle-protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc Natl Acad Sci USA, 2007, 104: 2050-2055