Platelets, but not erythrocytes, significantly affect cytokine release and scaffold contraction in a provisional scaffold model

Wound Repair and Regeneration

Volumn 16, Issue 3, 2008, Pages 370-378

  Jacobson, May ^b   Fufa, Duretti ^a   Abreu, Eduardo L ^a   Kevy, Sherwin ^b   Murray, Martha M ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GROWTH FACTOR; THROMBOCYTE CONCENTRATE;

ANTERIOR CRUCIATE LIGAMENT; ARTICLE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE; FIBROBLAST; GEL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; THROMBOCYTE; THROMBOCYTE COUNT; WOUND HEALING;

ANTERIOR CRUCIATE LIGAMENT; BLOOD PLATELETS; CELL PROLIFERATION; CYTOKINES; ERYTHROCYTES; FIBROBLASTS; HUMANS; MODELS, BIOLOGICAL; TISSUE SCAFFOLDS; WOUND HEALING;

EID: 43349083876     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/j.1524-475X.2008.00376.x     Document Type: Article

References (40)

1. Spindler KP, Dawson JM, Stahlman GC, Davidson JM, Nanney LB. Collagen expression and biomechanical response to human recombinant transforming growth factor beta (rhTGF-beta2) in the healing rabbit MCL. J Orthop Res 2002 20 : 318 24.
2. Batten ML, Hansen JC, Dahners LE. Influence of dosage and timing of application of platelet-derived growth factor on early healing of the rat medial collateral ligament. J Orthop Res 1996 14 : 736 41.
3. Lee J, Harwood FL, Akeson WH, Amiel D. Growth factor expression in healing rabbit medial collateral and anterior cruciate ligaments. Iowa Orthop J 1998 18 : 19 25.
4. Kobayashi D, Kurosaka M, Yoshiya S, Mizuno K. Effect of basic fibroblast growth factor on the healing of defects in the canine anterior cruciate ligament [see comments]. Knee Surg Sports Traumatol Arthrosc 1997 5 : 189 94.
5. Pascher A, Steinert AF, Palmer GD, Betz O, Gouze JN, Gouze E, Pilapil C, Ghivizzani SC, Evans CH, Murray MM. Enhanced repair of the anterior cruciate ligament by in situ gene transfer: evaluation in an in vitro model. Mol Ther 2004 10 : 327 36.
6. Spindler KP, Murray MM, Detwiler KB, Tarter JT, Dawson JM, Nanney LB, Davidson JM. The biomechanical response to doses of TGF-beta 2 in the healing rabbit medial collateral ligament. J Orthop Res 2003 21 : 245 9.
7. Letson AK, Dahners LE. The effect of combinations of growth factors on ligament healing. Clin Orthop 1994 308 : 207 12.
8. Murray MM, Spindler KP, Devin C, Snyder BS, Muller J, Takahashi M, Ballard P, Nanney LB, Zurakowski D. Use of a collagen-platelet rich plasma scaffold to stimulate healing of a central defect in the canine ACL. J Orthop Res 2006 24 : 820 30.
9. Frechette JP, Martineau I, Gagnon G. Platelet-rich plasmas: growth factor content and roles in wound healing. J Dent Res 2005 84 : 434 9.
10. Anitua E, Andia I, Sanchez M, Azofra J, del Mar Zalduendo M, de la Fuente M, Nurden P, Nurden AT. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res 2005 23 : 281 6.
11. Kawase T, Okuda K, Wolff LF, Yoshie H. Platelet-rich plasma-derived fibrin clot formation stimulates collagen synthesis in periodontal ligament and osteoblastic cells in vitro. J Periodontol 2003 74 : 858 64.
12. MacNeil RL, D'Errico J, Strayhorn C, Pickrum H, Somerman MJ. Agents with periodontal regenerative potential regulate cell-mediated collagen lattice contraction in vitro. J Dent Res 1996 75 : 903 11.
13. Kawase T, Okuda K, Saito Y, Yoshie H. In vitro evidence that the biological effects of platelet-rich plasma on periodontal ligament cells is not mediated solely by constituent transforming-growth factor-beta or platelet-derived growth factor. J Periodontol 2005 76 : 760 7.
14. Murray MM, Rice K, Wright RJ, Spector M. The effect of selected growth factors on human anterior cruciate ligament cell interactions with a three-dimensional collagen-GAG scaffold. J Orthop Res 2003 21 : 238 44.
15. Grundstrom G, Mosher DF, Sakai T, Rubin K. Integrin alphavbeta3 mediates platelet-derived growth factor-BB-stimulated collagen gel contraction in cells expressing signaling deficient integrin alpha2beta1. Exp Cell Res 2003 291 : 463 73.
16. Katakami C, Raymond LA, Lipman MJ, Appel A, Kao WW. Change in the synthesis of glycosaminoglycans by fibrotic vitreous induced by erythrocytes. Biochim Biophys Acta 1986 880 : 40 5.
17. Fredriksson K, Liu XD, Lundahl J, Klominek J, Rennard SI, Skold CM. Red blood cells increase secretion of matrix metalloproteinases from human lung fibroblasts in vitro. Am J Physiol Lung Cell Mol Physiol 2006 290 : L326 33.
18. Fredriksson K, Lundahl J, Fernvik E, Liu XD, Rennard SI, Skold CM. Red blood cells stimulate fibroblast-mediated contraction of three dimensional collagen gels in co-culture. Inflamm Res 2002 51 : 245 51.
19. Fredriksson K, Stridh H, Lundahl J, Rennard SI, Skold CM. Red blood cells inhibit proliferation and stimulate apoptosis in human lung fibroblasts in vitro. Scand J Immunol 2004 59 : 559 65.
20. Neote K, Darbonne W, Ogez J, Horuk R, Schall TJ. Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells. J Biol Chem 1993 268 : 12247 9.
21. Zagai U, Fredriksson K, Rennard SI, Lundahl J, Skold CM. Platelets stimulate fibroblast-mediated contraction of collagen gels. Respir Res 2003 4 : 13.
22. Eppley BL, Woodell JE, Higgins J. Platelet quantification and growth factor analysis from platelet-rich plasma: implications for wound healing. Plast Reconstr Surg 2004 114 : 1502 8.
23. Okuda K, Kawase T, Momose M, Murata M, Saito Y, Suzuki H, Wolff LF, Yoshie H. Platelet-rich plasma contains high levels of platelet-derived growth factor and transforming growth factor-beta and modulates the proliferation of periodontally related cells in vitro. J Periodontol 2003 74 : 849 57.
24. Wang XL, Liu SX, Wilcken DE. Circulating transforming growth factor beta 1 and coronary artery disease. Cardiovasc Res 1997 34 : 404 10.
25. Clausen T, Djurovic S, Reseland JE, Berg K, Drevon CA, Henriksen T. Altered plasma concentrations of leptin, transforming growth factor-beta(1) and plasminogen activator inhibitor type 2 at 18 weeks of gestation in women destined to develop pre-eclampsia. Circulating markers of disturbed placentation? Placenta 2002 23 : 380 5.
26. Dziadzio M, Smith RE, Abraham DJ, Black CM, Denton CP. Circulating levels of active transforming growth factor beta1 are reduced in diffuse cutaneous systemic sclerosis and correlate inversely with the modified Rodnan skin score. Rheumatology (Oxford) 2005 44 : 1518 24.
27. Fava R, Olsen N, Keski-Oja J, Moses H, Pincus T. Active and latent forms of transforming growth factor beta activity in synovial effusions. J Exp Med 1989 169 : 291 6.
28. Sanderson N, Factor V, Nagy P, Kopp J, Kondaiah P, Wakefield L, Roberts AB, Sporn MB, Thorgeirsson SS. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions. Proc Natl Acad Sci USA 1995 92 : 2572 6.
29. Hsu C, Chang J. Clinical implications of growth factors in flexor tendon wound healing. J Hand Surg [Am] 2004 29 : 551 63.
30. Le AD, Zhang Q, Wu Y, Messadi DV, Akhondzadeh A, Nguyen AL, Aghaloo TL, Kelly AP, Bertolami CN. Elevated vascular endothelial growth factor in keloids: relevance to tissue fibrosis. Cells Tissues Organs 2004 176 : 87 94.
31. Ohtani K, Egashira K, Hiasa K, Zhao Q, Kitamoto S, Ishibashi M, Usui M, Inouye S, Yonemitsu Y, Sueishi K, Sata M, Shibuya M, Sunagawa K. Blockade of vascular endothelial growth factor suppresses experimental restenosis after intraluminal injury by inhibiting recruitment of monocyte lineage cells. Circulation 2004 110 : 2444 52.
32. Herve MA, Buteau-Lozano H, Mourah S, Calvo SF, Perrot-Applanat M. VEGF189 stimulates endothelial cells proliferation and migration in vitro and up-regulates the expression of Flk-1/KDR mRNA. Exp Cell Res 2005 309 : 24 31.
33. Lee SS, Joo YS, Kim WU, Min DJ, Min JK, Park SH, Cho CS, Kim HY. Vascular endothelial growth factor levels in the serum and synovial fluid of patients with rheumatoid arthritis. Clin Exp Rheumatol 2001 19 : 321 4.
34. Nielsen HJ, Werther K, Mynster T, Brunner N. Soluble vascular endothelial growth factor in various blood transfusion components. Transfusion 1999 39 : 1078 83.
35. Garrett Q, Khaw PT, Blalock TD, Schultz GS, Grotendorst GR, Daniels JT. Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress. Invest Ophthalmol Vis Sci 2004 45 : 1109 16.
36. Jen CJ, McIntire LV. The structural properties and contractile force of a clot. Cell Motil 1982 2 : 445 55.
37. Matsuda N, Lin WL, Kumar NM, Cho MI, Genco RJ. Mitogenic, chemotactic, and synthetic responses of rat periodontal ligament fibroblastic cells to polypeptide growth factors in vitro. J Periodontol 1992 63 : 515 25.
38. Murray MM, Forsythe B, Chen F, Lee SJ, Yoo JJ, Atala A, Steinert A. The effect of thrombin on ACL fibroblast interactions with collagen hydrogels. J Orthop Res 2006 24 : 508 15.
39. Murray MM, Spindler KP, Abreu E, Muller JA, Nedder A, Kelly M, Frino J, Zurakowski D, Valenza M, Snyder BD, Connolly SA. Collagen-platelet rich plasma hydrogel enhances primary repair of the porcine anterior cruciate ligament. J Orthop Res 2007 25 : 81 91.
40. Murray MM, Spindler KP, Ballard P, Welch TP, Zurakowski D, Nanney LB. Enhanced histologic repair in a central wound in the anterior cruciate ligament with a collagen-platelet-rich plasma scaffold. J Orthop Res 2007 25 : 1007 17.